MABC565MI
MilliporeSigma™ Mouse anti-SPOP, Clone: 9B7.1,
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | MABC565MI-Each-of-1 | In Stock | ₹ 43,067.48 |
MABC565MI - Each of 1
In Stock
Quantity
1
Base Price: ₹ 43,067.48
GST (18%): ₹ 7,752.146
Total Price: ₹ 50,819.626
Antigen
SPOP
Classification
Monoclonal
Formulation
Purified mouse monoclonal IgG2aκ in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols
SPOP
Immunogen
GST-tagged recombinant protein corresponding to human SPOP.
Quantity
100 μg
Research Discipline
Apoptosis, Cancer
Gene ID (Entrez)
NP_001007227
Content And Storage
Stable for one year at 2°C to 8°C from date of receipt.
Isotype
IgG2a κ
Applications
Immunohistochemistry, Western Blot
Clone
9B7.1
Gene Accession No.
O43791
Host Species
Mouse
Purification Method
Protein G Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Target Species
Human
Form
Purified
Related Products
Description
- Specifically detects SPOP clone: 9B7.1 in Human samples, and it is validated for Immunohistochemistry, Western Blotting Speckle-type pox virus and zinc finger (POZ) protein, also known as HIB homolog 1 or Roadkill homolog 1, is encoded by the SPOP gene (also known as TEF2 or BTBD32) in human (Entrez Gene ID 8405)
- SPOP protein is a component of cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex and mediates recruitment of target proteins containing the SPOP-binding consensus (SBC) motif
- The 42kDa SPOP protein comprises an N-terminal MATH domain, a bric-a-brac, tramtrack and broad complex (BTB)/POZ domain, a 3-box domain, and a C-terminal nuclear localization sequence
- The MATH domain is primarily involved in substrate recognition/binding
- Known substrates with SBC motifs include Macro H2A, Puc (Puckered), Daxx (Death domain–associated protein), and Gli (Glioma-associated oncogene)
- Prostate and endometrial cancers are frequently identified with SPOP mutations in the meprin and TRAF (Tumor necrosis factor receptor-associated factor) homology (MATH) domain, which can potentially lead to altered substrate binding activities
- (PMID 25058385)
- The SPOP protein sequence is 100% conserved among human, murine, and rat (UniProt O43791, Q6ZWS8, and B2RYD9, respectively) species
- Anti-SPOP, clone 9B7.1, is a purified mouse monoclonal antibody
- A GST fusion protein containing the full-lenght human SPOP sequence was used as the immunogen
- The binding epitope of clone 9B7.1 has not yet been mapped.
Compare Similar Items
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Antigen: SPOP
Classification: Monoclonal
Formulation: Purified mouse monoclonal IgG2aκ in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols: SPOP
Immunogen: GST-tagged recombinant protein corresponding to human SPOP.
Quantity: 100 μg
Research Discipline: Apoptosis, Cancer
Gene ID (Entrez): NP_001007227
Content And Storage: Stable for one year at 2°C to 8°C from date of receipt.
Isotype: IgG2a κ
Applications: Immunohistochemistry, Western Blot
Clone: 9B7.1
Gene Accession No.: O43791
Host Species: Mouse
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human
Form: Purified
Antigen:
SPOP
Classification:
Monoclonal
Formulation:
Purified mouse monoclonal IgG2aκ in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols:
SPOP
Immunogen:
GST-tagged recombinant protein corresponding to human SPOP.
Quantity:
100 μg
Research Discipline:
Apoptosis, Cancer
Gene ID (Entrez):
NP_001007227
Content And Storage:
Stable for one year at 2°C to 8°C from date of receipt.
Isotype:
IgG2a κ
Applications:
Immunohistochemistry, Western Blot
Clone:
9B7.1
Gene Accession No.:
O43791
Host Species:
Mouse
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Human
Form:
Purified
Antigen: Somatoliberin/GHRH
Classification: Monoclonal
Formulation: Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols: GHRH; GHRF
Immunogen: KLH-conjugated linear peptide corresponding to mature human somatoliberin sequence.
Quantity: 100 μg
Research Discipline: Apoptosis, Cancer
Gene ID (Entrez): NP_001171660
Content And Storage: Stable for one year at 2°C to 8°C from date of receipt.
Isotype: IgG1 κ
Applications: Immunohistochemistry (Paraffin), Western Blot
Clone: 1B4.2
Gene Accession No.: P01286
Host Species: Mouse
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human
Form: Purified
Antigen:
Somatoliberin/GHRH
Classification:
Monoclonal
Formulation:
Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols:
GHRH; GHRF
Immunogen:
KLH-conjugated linear peptide corresponding to mature human somatoliberin sequence.
Quantity:
100 μg
Research Discipline:
Apoptosis, Cancer
Gene ID (Entrez):
NP_001171660
Content And Storage:
Stable for one year at 2°C to 8°C from date of receipt.
Isotype:
IgG1 κ
Applications:
Immunohistochemistry (Paraffin), Western Blot
Clone:
1B4.2
Gene Accession No.:
P01286
Host Species:
Mouse
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Human
Form:
Purified
Antigen: Sec8/Exoc4
Classification: Monoclonal
Formulation: Purified mouse monoclonal IgG2bκ in buffer containing 0.1MTris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols: Exoc4, Sec8, Sec8l1
Immunogen: Recombinant protein corresponding to rat Sec8/Exoc4.
Quantity: 100 μg
Research Discipline: __
Gene ID (Entrez): __
Content And Storage: 2-8°C for one year
Isotype: IgG2b κ
Applications: Immunocytochemistry, Western Blot
Clone: 2E12
Gene Accession No.: NP_446327
Host Species: Mouse
Purification Method: Protein G purified
Regulatory Status: __
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Form: Purified
Antigen:
Sec8/Exoc4
Classification:
Monoclonal
Formulation:
Purified mouse monoclonal IgG2bκ in buffer containing 0.1MTris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols:
Exoc4, Sec8, Sec8l1
Immunogen:
Recombinant protein corresponding to rat Sec8/Exoc4.
Quantity:
100 μg
Research Discipline:
__
Gene ID (Entrez):
__
Content And Storage:
2-8°C for one year
Isotype:
IgG2b κ
Applications:
Immunocytochemistry, Western Blot
Clone:
2E12
Gene Accession No.:
NP_446327
Host Species:
Mouse
Purification Method:
Protein G purified
Regulatory Status:
__
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Form:
Purified
Antigen: c-Ret
Classification: Monoclonal
Formulation: Purified mouse monoclonal IgG1κ in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols: RET, CDHF12, CDHR16, PTC, RET51
Immunogen: GST-tagged recombinant protein corresponding to the extracellular domain of human c-Ret.
Quantity: 100 μg
Research Discipline: Apoptosis, Cancer
Gene ID (Entrez): NP_066124
Content And Storage: 2°C to 8°C for one year from date of shipment
Isotype: IgG1 κ
Applications: Western Blot
Clone: 6F3.1
Gene Accession No.: P07949
Host Species: Mouse
Purification Method: Protein G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Rat
Form: Purified
Antigen:
c-Ret
Classification:
Monoclonal
Formulation:
Purified mouse monoclonal IgG1κ in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols:
RET, CDHF12, CDHR16, PTC, RET51
Immunogen:
GST-tagged recombinant protein corresponding to the extracellular domain of human c-Ret.
Quantity:
100 μg
Research Discipline:
Apoptosis, Cancer
Gene ID (Entrez):
NP_066124
Content And Storage:
2°C to 8°C for one year from date of shipment
Isotype:
IgG1 κ
Applications:
Western Blot
Clone:
6F3.1
Gene Accession No.:
P07949
Host Species:
Mouse
Purification Method:
Protein G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Rat
Form:
Purified