MABC572MI

MilliporeSigma™ anti-c-Ret Clone: 6F3.1,

Manufacturer: MilliporeSigma™

Select a Size

Pack Size SKU Availability Price
Each of 1 MABC572MI-Each-of-1 In Stock ₹ 48,852.19

MABC572MI - Each of 1

₹ 48,852.19

In Stock

Quantity

1

Base Price: ₹ 48,852.19

GST (18%): ₹ 8,793.394

Total Price: ₹ 57,645.584

Antigen

c-Ret

Classification

Monoclonal

Conjugate

Unconjugated

Gene Accession No.

P07949

Host Species

Mouse

Purification Method

Protein G purified

Regulatory Status

RUO

Primary or Secondary

Primary

Test Specificity

Expected to react with both the RET51 and the RET9 isoforms, as well as the extracellular cell-membrane anchored RET cadherin 120kDa fragment (a.a. 29-707).

Content And Storage

2°C to 8°C for one year from date of shipment

Isotype

IgG1 κ

Applications

Western Blot

Clone

6F3.1

Formulation

Purified mouse monoclonal IgG1κ in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.

Gene Symbols

RET, CDHF12, CDHR16, PTC, RET51

Immunogen

GST-tagged recombinant protein corresponding to the extracellular domain of human c-Ret.

Quantity

100 μg

Research Discipline

Apoptosis, Cancer

Gene ID (Entrez)

NP_066124

Target Species

Rat

Form

Purified

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Description

  • Specifically detects c-Ret Clone: 6F3.1 in Rat samples, and it is validated for Western Blotting Proto-oncogene tyrosine-protein kinase receptor Ret (EC 2.7.10.1; UniProt P07949; also known as Cadherin family member 12, Cadherin-related family member 16, Hydroxyaryl-protein kinase, Proto-oncogene c-Ret, Rearranged during transfection, Receptor tyrosine kinase, Ret proto-oncogene, RET receptor tyrosine kinase, RET transforming sequence) is encoded by the RET (also known as CDHF12, CDHR16, HSCR1, MEN2A, MEN2B, MTC1, PTC, RET-ELE1, RET51) gene (Gene ID 5979) in human
  • Ret is a receptor tyrosine kinase that mediates the activation of several signaling pathways including the PLC gamma, Ras, JNK and inositol phosphate pathways
  • Ret mutations have been shown to be causative in several diseases, including Hirschsprung's disease (HD), papillary thyroid carcinoma, multiple endocrine neoplasia (MEN) 2A, MEN 2B, and familial medullary thyroid carcinoma
  • Ret is initially produced with a signal peptide sequence (a.a
  • 1-28), the removal of which yields the mature Ret (a.a
  • 20-1114)
  • Ret can be posttranslationally cleaved into the extracellular cell-membrane-anchored RET cadherin 120kDa fragment (a.a
  • 29-707) and the soluble RET kinase fragment (a.a
  • 708-1017).

Compare Similar Items

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MilliporeSigma™

MABC572MI

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Antigen:
c-Ret

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene Accession No.:
P07949

Host Species:
Mouse

Purification Method:
Protein G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
Expected to react with both the RET51 and the RET9 isoforms, as well as the extracellular cell-membrane anchored RET cadherin 120kDa fragment (a.a. 29-707).

Content And Storage:
2°C to 8°C for one year from date of shipment

Isotype:
IgG1 κ

Applications:
Western Blot

Clone:
6F3.1

Formulation:
Purified mouse monoclonal IgG1κ in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.

Gene Symbols:
RET, CDHF12, CDHR16, PTC, RET51

Immunogen:
GST-tagged recombinant protein corresponding to the extracellular domain of human c-Ret.

Quantity:
100 μg

Research Discipline:
Apoptosis, Cancer

Gene ID (Entrez):
NP_066124

Target Species:
Rat

Form:
Purified

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MilliporeSigma™

MABC573MI

--


Antigen:
Bcl-2

Classification:
Monoclonal

Conjugate:
__

Gene Accession No.:
P10417

Host Species:
Rat

Purification Method:
Protein G Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
__

Content And Storage:
Stable for one year at 2°C to 8°C from date of receipt.

Isotype:
IgG2a κ

Applications:
Western Blot

Clone:
1D7.2

Formulation:
Purified rat monoclonal IgG2aκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.

Gene Symbols:
Bcl2; Bcl-2

Immunogen:
GST-tagged recombinant protein corresponding to the N-terminal of mouse Bcl-2.

Quantity:
100 μg

Research Discipline:
Apoptosis, Cancer

Gene ID (Entrez):
NP_033871

Target Species:
Mouse

Form:
Purified

Img

MilliporeSigma™

MABC576MI

--


Antigen:
HOIL-1

Classification:
Monoclonal

Conjugate:
__

Gene Accession No.:
Q9BYM8

Host Species:
Mouse

Purification Method:
Protein G Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
__

Content And Storage:
Stable for one year at 2°C to 8°C from date of receipt.

Isotype:
IgG1 κ

Applications:
Immunocytochemistry, Western Blot

Clone:
2E2

Formulation:
Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.

Gene Symbols:
RBCK1; C20orf18; RNF54; UBCE7IP3; XAP3; XAP4

Immunogen:
GST-tagged recombinant protein corresponding to human HOIL-1 near the C-terminus.

Quantity:
100 μg

Research Discipline:
Apoptosis, Cancer

Gene ID (Entrez):
NP_006453

Target Species:
Human, Mouse

Form:
Purified

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Sigma Aldrich

MABC580

clone 6F10.1, from mouse...


Antigen:
__

Classification:
__

Conjugate:
__

Gene Accession No.:
__

Host Species:
__

Purification Method:
__

Regulatory Status:
__

Primary or Secondary:
__

Test Specificity:
__

Content And Storage:
__

Isotype:
__

Applications:
__

Clone:
__

Formulation:
__

Gene Symbols:
__

Immunogen:
__

Quantity:
__

Research Discipline:
__

Gene ID (Entrez):
__

Target Species:
__

Form:
__