MABS432MI
MilliporeSigma™ anti-MEK1 Clone: 6B7.1,
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | MABS432MI-Each-of-1 | In Stock | ₹ 38,734.72 |
MABS432MI - Each of 1
In Stock
Quantity
1
Base Price: ₹ 38,734.72
GST (18%): ₹ 6,972.25
Total Price: ₹ 45,706.97
Antigen
MEK1
Classification
Monoclonal
Conjugate
Unconjugated
Gene Accession No.
Q02750
Host Species
Mouse
Purification Method
Protein G purified
Regulatory Status
RUO
Primary or Secondary
Primary
Test Specificity
Expected to react with both the MKK1a and MKK1b spliced isoforms.
Content And Storage
2°C to 8°C for one year from date of shipment
Isotype
IgG2a κ
Applications
Western Blot
Clone
6B7.1
Formulation
Purified mouse monoclonal IgG2aκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols
MAP2K1, MEK1, PRKMK1
Immunogen
GST-tagged recombinant protein corresponding to the C-terminal region of human MEK1.
Quantity
100 μg
Research Discipline
Signaling
Gene ID (Entrez)
NP_002746
Target Species
Human
Form
Purified
Related Products
Description
- Specifically detects MEK1 Clone: 6B7.1 in Human samples, and it is validated for Western Blotting Dual specificity mitogen-activated protein kinase kinase 1 (EC 2.7.12.2; UniProt Q02750; also known as ERK activator kinase 1, MAP kinase kinase 1, MAPK/ERK kinase 1, MAPKK 1, MEK 1, MKK1) is encoded by the MAP2K1 (also known as CFC3, MAPKK1, MEK1, MKK1, PRKMK1) gene (Gene ID 5604) in human
- MEK1 and the related MEK2 are dual specificity kinases of the MAP2K/STE7 kinase family
- MEK1 and MEK2 share a high degree of sequence homology and perform similar functions
- Upon activation by RAF, MEK1/2 catalyze the dual phosphorylation of threonine and tyrosine residues on ERK (MAPK) within a specific Thr-Glu-Tyr sequence at codons 202 to 204
- This locks the kinase domain of MAPK into a catalytically competent conformation, ultimately leading to nuclear signals that regulate cellular growth and proliferation
- MEK1/2 mutations have been reported to be associated with cardiofaciocutaneous syndrome 3 (CFC3) and cancers, including lung cancer, colorectal cancer, and melanomas.
Compare Similar Items
Show Difference
Antigen: MEK1
Classification: Monoclonal
Conjugate: Unconjugated
Gene Accession No.: Q02750
Host Species: Mouse
Purification Method: Protein G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Expected to react with both the MKK1a and MKK1b spliced isoforms.
Content And Storage: 2°C to 8°C for one year from date of shipment
Isotype: IgG2a κ
Applications: Western Blot
Clone: 6B7.1
Formulation: Purified mouse monoclonal IgG2aκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols: MAP2K1, MEK1, PRKMK1
Immunogen: GST-tagged recombinant protein corresponding to the C-terminal region of human MEK1.
Quantity: 100 μg
Research Discipline: Signaling
Gene ID (Entrez): NP_002746
Target Species: Human
Form: Purified
Antigen:
MEK1
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene Accession No.:
Q02750
Host Species:
Mouse
Purification Method:
Protein G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Expected to react with both the MKK1a and MKK1b spliced isoforms.
Content And Storage:
2°C to 8°C for one year from date of shipment
Isotype:
IgG2a κ
Applications:
Western Blot
Clone:
6B7.1
Formulation:
Purified mouse monoclonal IgG2aκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols:
MAP2K1, MEK1, PRKMK1
Immunogen:
GST-tagged recombinant protein corresponding to the C-terminal region of human MEK1.
Quantity:
100 μg
Research Discipline:
Signaling
Gene ID (Entrez):
NP_002746
Target Species:
Human
Form:
Purified
Antigen: PCSK9
Classification: Monoclonal
Conjugate: Unconjugated
Gene Accession No.: Q8NBP7
Host Species: Mouse
Purification Method: Unpurified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Clone 9B3.1 detects the precursor and mature forms of human PCSK9 (NARC-1) by targeting an epitope within the N-terminal region of the mature sequence.
Content And Storage: Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Isotype: IgG2a κ
Applications: Western Blot
Clone: 9B3.1
Formulation: Mouse IgG2a hybridoma culture supernatant without azide.
Gene Symbols: __
Immunogen: GST-tagged recombinant human mature NARC-1 (PCSK9) N-terminal fragment.
Quantity: 200 μL
Research Discipline: Signaling
Gene ID (Entrez): NP_777596
Target Species: Human
Form: Culture Supernatant
Antigen:
PCSK9
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene Accession No.:
Q8NBP7
Host Species:
Mouse
Purification Method:
Unpurified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Clone 9B3.1 detects the precursor and mature forms of human PCSK9 (NARC-1) by targeting an epitope within the N-terminal region of the mature sequence.
Content And Storage:
Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Isotype:
IgG2a κ
Applications:
Western Blot
Clone:
9B3.1
Formulation:
Mouse IgG2a hybridoma culture supernatant without azide.
Gene Symbols:
__
Immunogen:
GST-tagged recombinant human mature NARC-1 (PCSK9) N-terminal fragment.
Quantity:
200 μL
Research Discipline:
Signaling
Gene ID (Entrez):
NP_777596
Target Species:
Human
Form:
Culture Supernatant
Antigen: WBP2
Classification: Monoclonal
Conjugate: Unconjugated
Gene Accession No.: NP_036610
Host Species: Mouse
Purification Method: Protein G purified
Regulatory Status: __
Primary or Secondary: Primary
Test Specificity: __
Content And Storage: 2-8°C for one year
Isotype: IgG1 κ
Applications: Immunocytochemistry, Immunoprecipitation, Western Blot
Clone: 4C8H10
Formulation: Purified mouse monoclonal IgG1κ in buffer containing 0.1MTris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols: WBP2
Immunogen: GST-tagged full length recombinant protein corresponding to Human WBP2.
Quantity: 100 μL
Research Discipline: __
Gene ID (Entrez): __
Target Species: Human
Form: Purified
Antigen:
WBP2
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene Accession No.:
NP_036610
Host Species:
Mouse
Purification Method:
Protein G purified
Regulatory Status:
__
Primary or Secondary:
Primary
Test Specificity:
__
Content And Storage:
2-8°C for one year
Isotype:
IgG1 κ
Applications:
Immunocytochemistry, Immunoprecipitation, Western Blot
Clone:
4C8H10
Formulation:
Purified mouse monoclonal IgG1κ in buffer containing 0.1MTris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols:
WBP2
Immunogen:
GST-tagged full length recombinant protein corresponding to Human WBP2.
Quantity:
100 μL
Research Discipline:
__
Gene ID (Entrez):
__
Target Species:
Human
Form:
Purified
Antigen: __
Classification: __
Conjugate: __
Gene Accession No.: __
Host Species: __
Purification Method: __
Regulatory Status: __
Primary or Secondary: __
Test Specificity: __
Content And Storage: __
Isotype: __
Applications: __
Clone: __
Formulation: __
Gene Symbols: __
Immunogen: __
Quantity: __
Research Discipline: __
Gene ID (Entrez): __
Target Species: __
Form: __
Antigen:
__
Classification:
__
Conjugate:
__
Gene Accession No.:
__
Host Species:
__
Purification Method:
__
Regulatory Status:
__
Primary or Secondary:
__
Test Specificity:
__
Content And Storage:
__
Isotype:
__
Applications:
__
Clone:
__
Formulation:
__
Gene Symbols:
__
Immunogen:
__
Quantity:
__
Research Discipline:
__
Gene ID (Entrez):
__
Target Species:
__
Form:
__