MABC945MI
MilliporeSigma™ anti- TRIM3 Clone: 13D12.1,
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | MABC945MI-Each-of-1 | In Stock | ₹ 48,852.19 |
MABC945MI - Each of 1
In Stock
Quantity
1
Base Price: ₹ 48,852.19
GST (18%): ₹ 8,793.394
Total Price: ₹ 57,645.584
Antigen
TRIM3
Classification
Monoclonal
Conjugate
Unconjugated
Gene Accession No.
O75382
Host Species
Mouse
Purification Method
Protein G purified
Regulatory Status
RUO
Primary or Secondary
Primary
Test Specificity
Expected to react with all four spliced isoforms.
Content And Storage
2°C to 8°C for one year from date of shipment
Isotype
IgG1 κ
Applications
Immunohistochemistry, Western Blot
Clone
13D12.1
Formulation
Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols
TRIM3, BERP, RNF22, RNF97
Immunogen
GST-tagged recombinant protein corresponding to the internal fragment of human TRIM3.
Quantity
100 μg
Research Discipline
Apoptosis, Cancer
Gene ID (Entrez)
NP_001234935
Target Species
Human, Mouse, Rat
Form
Purified
Related Products
Description
- Specifically detects TRIM3 Clone: 13D12.1 in Human, Mouse, Rat samples, and it is validated for Immunohistochemistry, Western Blotting Tripartite motif-containing protein 3 (UniProt O75382; also known as Brain-expressed RING finger protein, RING finger protein 22, Ring finger protein 97, Tripartite motif protein TRIM3, Tripartite motif-containing 3) is encoded by the TRIM3 (also known as BERP, HAC1, RNF22, RNF97) gene (Gene ID 10612) in human
- TRIM3 belongs to a family of more than 70 TRIM/RBCC proteins characterized by their shared tripartite motif structure, also known as the RBCC (RING finger, B-box, and coiled-coil) domain
- The B-box and coiled coil regions are believed to participate in protein-protein interactions and formation of macromolecular complexes
- TRIM proteins are involved in diverse cellular processes, including cell proliferation, differentiation, oncogenesis, and apoptosis
- The presence of a RING domain suggests that TRIM proteins function as E3 ubiquitin ligases
- TRIM3 is reported to catalyze the transfer of ubiquitin from UbcH5a to p21, a protein necessary for the proliferation of a subset of PDGF (platelet-derived growth factor)-transformed proneural glioma cells
- Loss of TRIM3 heterozygosity is found in more than 10% of human GBMs (glioblastomas), while reducing TRIM3 expression facilitates tumor development and accelerates the progression of oligodendroglioma in a mouse model.
Compare Similar Items
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Antigen: TRIM3
Classification: Monoclonal
Conjugate: Unconjugated
Gene Accession No.: O75382
Host Species: Mouse
Purification Method: Protein G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Expected to react with all four spliced isoforms.
Content And Storage: 2°C to 8°C for one year from date of shipment
Isotype: IgG1 κ
Applications: Immunohistochemistry, Western Blot
Clone: 13D12.1
Formulation: Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols: TRIM3, BERP, RNF22, RNF97
Immunogen: GST-tagged recombinant protein corresponding to the internal fragment of human TRIM3.
Quantity: 100 μg
Research Discipline: Apoptosis, Cancer
Gene ID (Entrez): NP_001234935
Target Species: Human, Mouse, Rat
Form: Purified
Antigen:
TRIM3
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene Accession No.:
O75382
Host Species:
Mouse
Purification Method:
Protein G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Expected to react with all four spliced isoforms.
Content And Storage:
2°C to 8°C for one year from date of shipment
Isotype:
IgG1 κ
Applications:
Immunohistochemistry, Western Blot
Clone:
13D12.1
Formulation:
Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols:
TRIM3, BERP, RNF22, RNF97
Immunogen:
GST-tagged recombinant protein corresponding to the internal fragment of human TRIM3.
Quantity:
100 μg
Research Discipline:
Apoptosis, Cancer
Gene ID (Entrez):
NP_001234935
Target Species:
Human, Mouse, Rat
Form:
Purified
Antigen: Glycoprotein 78
Classification: Monoclonal
Conjugate: Unconjugated
Gene Accession No.: Q9UKV5
Host Species: Rat
Purification Method: Purified by Ion-Exchange Chromatography
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Clone 3F3A detected glycoprotein 78 (gp78) and a ∽150 kDa glycoprotein in B16-F1 mouse melanoma cell extract. Cell extract sialidase treatment decreased the antibody's immunoreactivity toward gp78 and abolished ∽150 kDa band detection (Nabi, I.R., et al. (1990). Cancer Res. 50(2):409-414).
Content And Storage: Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Isotype: IgM κ
Applications: Immunocytochemistry, Immunohistochemistry, Western Blot
Clone: 3F3A
Formulation: Purified rat IgM in buffer containing PBS without azide.
Gene Symbols: __
Immunogen: Peanut lectin (PNA) resin-purified membrane glycoprotein 78 from B16-F1 cells (Nabi, I.R., and Raz, A. (1987). Int. J. Cancer. 40(3):396-402).
Quantity: 200 μL
Research Discipline: Apoptosis & Cancer
Gene ID (Entrez): NP_001135
Target Species: Human
Form: Purified
Antigen:
Glycoprotein 78
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene Accession No.:
Q9UKV5
Host Species:
Rat
Purification Method:
Purified by Ion-Exchange Chromatography
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Clone 3F3A detected glycoprotein 78 (gp78) and a ∽150 kDa glycoprotein in B16-F1 mouse melanoma cell extract. Cell extract sialidase treatment decreased the antibody's immunoreactivity toward gp78 and abolished ∽150 kDa band detection (Nabi, I.R., et al. (1990). Cancer Res. 50(2):409-414).
Content And Storage:
Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Isotype:
IgM κ
Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot
Clone:
3F3A
Formulation:
Purified rat IgM in buffer containing PBS without azide.
Gene Symbols:
__
Immunogen:
Peanut lectin (PNA) resin-purified membrane glycoprotein 78 from B16-F1 cells (Nabi, I.R., and Raz, A. (1987). Int. J. Cancer. 40(3):396-402).
Quantity:
200 μL
Research Discipline:
Apoptosis & Cancer
Gene ID (Entrez):
NP_001135
Target Species:
Human
Form:
Purified
Antigen: Sphingosine 1-phosphate receptor 1 (S1P1)
Classification: Monoclonal
Conjugate: Unconjugated
Gene Accession No.: NP_001391
Host Species: Mouse
Purification Method: Protein G purified
Regulatory Status: __
Primary or Secondary: Primary
Test Specificity: __
Content And Storage: 2-8°C for one year
Isotype: IgG1 κ
Applications: Immunohistochemistry, Western Blot
Clone: 8B7.1
Formulation: Purified mouse monoclonal IgG1κ supernatant in buffer containing 0.1MTris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols: S1PR1, CHEDG1, EDG1
Immunogen: GST-tagged recombinant protein corresponding to mouse Sphingosine 1-phosphate receptor 1 (S1P1).
Quantity: 100 μL
Research Discipline: __
Gene ID (Entrez): __
Target Species: Human, Mouse, Rat
Form: Purified
Antigen:
Sphingosine 1-phosphate receptor 1 (S1P1)
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene Accession No.:
NP_001391
Host Species:
Mouse
Purification Method:
Protein G purified
Regulatory Status:
__
Primary or Secondary:
Primary
Test Specificity:
__
Content And Storage:
2-8°C for one year
Isotype:
IgG1 κ
Applications:
Immunohistochemistry, Western Blot
Clone:
8B7.1
Formulation:
Purified mouse monoclonal IgG1κ supernatant in buffer containing 0.1MTris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols:
S1PR1, CHEDG1, EDG1
Immunogen:
GST-tagged recombinant protein corresponding to mouse Sphingosine 1-phosphate receptor 1 (S1P1).
Quantity:
100 μL
Research Discipline:
__
Gene ID (Entrez):
__
Target Species:
Human, Mouse, Rat
Form:
Purified
Antigen: Aminopeptidase N/CD13
Classification: Monoclonal
Conjugate: __
Gene Accession No.: P97449
Host Species: Rat
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: __
Content And Storage: Stable for one year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles which may damage IgG and affect product performance.
Isotype: IgG2b κ
Applications: Functional Assay, Immunocytochemistry, Immunohistochemistry (Paraffin)
Clone: SL13
Formulation: Purified rat monoclonal IgG2bκ in buffer containing PBS without preservatives.
Gene Symbols: Anpep; Lap-1; Lap1
Immunogen: Recombinant protein corresponding to mouse Aminopeptidase N/CD13.
Quantity: 100 μg
Research Discipline: Apoptosis, Cancer
Gene ID (Entrez): NP_032512
Target Species: Mouse
Form: Purified
Antigen:
Aminopeptidase N/CD13
Classification:
Monoclonal
Conjugate:
__
Gene Accession No.:
P97449
Host Species:
Rat
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
__
Content And Storage:
Stable for one year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles which may damage IgG and affect product performance.
Isotype:
IgG2b κ
Applications:
Functional Assay, Immunocytochemistry, Immunohistochemistry (Paraffin)
Clone:
SL13
Formulation:
Purified rat monoclonal IgG2bκ in buffer containing PBS without preservatives.
Gene Symbols:
Anpep; Lap-1; Lap1
Immunogen:
Recombinant protein corresponding to mouse Aminopeptidase N/CD13.
Quantity:
100 μg
Research Discipline:
Apoptosis, Cancer
Gene ID (Entrez):
NP_032512
Target Species:
Mouse
Form:
Purified