MABE971MI
MilliporeSigma™ anti-HNF-1-beta Clone: 12A5.1,
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | MABE971MI-Each-of-1 | In Stock | ₹ 45,381.02 |
MABE971MI - Each of 1
In Stock
Quantity
1
Base Price: ₹ 45,381.02
GST (18%): ₹ 8,168.584
Total Price: ₹ 53,549.604
Antigen
HNF-1-beta
Classification
Monoclonal
Conjugate
Unconjugated
Gene Accession No.
P35680
Host Species
Mouse
Purification Method
Protein G purified
Regulatory Status
RUO
Primary or Secondary
Primary
Test Specificity
Expected to react with isoform 1 (A) and isoform 3 (C). Reactivity toward isoform 2 (B) and isoform 4 has not been determined.
Content And Storage
2°C to 8°C for one year from date of shipment
Isotype
IgG2a κ
Applications
Immunohistochemistry, Western Blot
Clone
12A5.1
Formulation
Purified mouse monoclonal IgG2aκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols
HNF1B, TCF2
Immunogen
GST-tagged recombinant protein corresponding to the Internal (N-terminal half) of human HNF-1-beta.
Quantity
100 μg
Research Discipline
Epigenetics, Nuclear Function
Gene ID (Entrez)
NP_000449
Target Species
Human, Rat
Form
Purified
Related Products
Description
- Specifically detects HNF-1-beta Clone: 12A5.1 in Human, Rat samples, and it is validated for Immunohistochemistry, Western Blotting Hepatocyte nuclear factor 1-beta (UniProt P35680; also known as HNF-1-beta, HNF-1B, Homeoprotein LFB3, TCF-2, Transcription factor 2, Variant hepatic nuclear factor 1, vHNF1) is encoded by the HNF1B (also known as TCF2, VHNF1) gene (Gene ID 6928) in human
- HNF-1-beta is involved in transcriptional and functional regulation of the liver and biliary system, as well as of the kidneys, urogenital tract and pancreatic β-cells
- HNF-1-beta deficiency due to HNF1B mutations is a well known cause of maturity-onset diabetes of the young 5 (MODY5), also referred to as RCAD (renal cysts and diabetes) due to the frequent co-occurrence of renal cysts and/or other inborn urogenital abnormalities
- HNF-1-beta is expressed in the gall bladder, liver and intrahepatic bile ducts of mouse embryos and in liver of adult mice
- HNF-1-beta is shown to co-regulate morphogenesis of the biliary system and HNF1B knockout mice suffer from severe neonatal cholestasis and jaundice due to the abnormally developed gall bladder and dysfunctional intrahepatic bile ducts.
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Antigen: HNF-1-beta
Classification: Monoclonal
Conjugate: Unconjugated
Gene Accession No.: P35680
Host Species: Mouse
Purification Method: Protein G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Expected to react with isoform 1 (A) and isoform 3 (C). Reactivity toward isoform 2 (B) and isoform 4 has not been determined.
Content And Storage: 2°C to 8°C for one year from date of shipment
Isotype: IgG2a κ
Applications: Immunohistochemistry, Western Blot
Clone: 12A5.1
Formulation: Purified mouse monoclonal IgG2aκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols: HNF1B, TCF2
Immunogen: GST-tagged recombinant protein corresponding to the Internal (N-terminal half) of human HNF-1-beta.
Quantity: 100 μg
Research Discipline: Epigenetics, Nuclear Function
Gene ID (Entrez): NP_000449
Target Species: Human, Rat
Form: Purified
Antigen:
HNF-1-beta
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene Accession No.:
P35680
Host Species:
Mouse
Purification Method:
Protein G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Expected to react with isoform 1 (A) and isoform 3 (C). Reactivity toward isoform 2 (B) and isoform 4 has not been determined.
Content And Storage:
2°C to 8°C for one year from date of shipment
Isotype:
IgG2a κ
Applications:
Immunohistochemistry, Western Blot
Clone:
12A5.1
Formulation:
Purified mouse monoclonal IgG2aκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols:
HNF1B, TCF2
Immunogen:
GST-tagged recombinant protein corresponding to the Internal (N-terminal half) of human HNF-1-beta.
Quantity:
100 μg
Research Discipline:
Epigenetics, Nuclear Function
Gene ID (Entrez):
NP_000449
Target Species:
Human, Rat
Form:
Purified
Antigen: PRDM5
Classification: Monoclonal
Conjugate: __
Gene Accession No.: Q9NQX1
Host Species: Mouse
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: __
Content And Storage: Stable for one year at 2°C to 8°C from date of receipt.
Isotype: IgG2b κ
Applications: Immunoprecipitation, Western Blot
Clone: 57-20
Formulation: Purified mouse monoclonal IgG2bκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols: PRDM5; PFM2
Immunogen: GST-tagged recombinant protein corresponding to human PRDM5 near the N-terminus.
Quantity: 200 μg
Research Discipline: Epigenetics and Nuclear Function
Gene ID (Entrez): NP_061169
Target Species: Mouse
Form: Purified
Antigen:
PRDM5
Classification:
Monoclonal
Conjugate:
__
Gene Accession No.:
Q9NQX1
Host Species:
Mouse
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
__
Content And Storage:
Stable for one year at 2°C to 8°C from date of receipt.
Isotype:
IgG2b κ
Applications:
Immunoprecipitation, Western Blot
Clone:
57-20
Formulation:
Purified mouse monoclonal IgG2bκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols:
PRDM5; PFM2
Immunogen:
GST-tagged recombinant protein corresponding to human PRDM5 near the N-terminus.
Quantity:
200 μg
Research Discipline:
Epigenetics and Nuclear Function
Gene ID (Entrez):
NP_061169
Target Species:
Mouse
Form:
Purified
Antigen: Ser/Thr-protein kinase Nek2
Classification: Monoclonal
Conjugate: __
Gene Accession No.: P51955
Host Species: Mouse
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: __
Content And Storage: Stable for one year at 2°C to 8°C from date of receipt.
Isotype: IgG2b κ
Applications: Immunocytochemistry, Western Blot
Clone: 5D2.1
Formulation: Purified mouse monoclonal IgG2bκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols: NEK2; NEK2A; NLK1
Immunogen: GST-tagged recombinant protein corresponding to the N-terminal of human Ser/Thr-protein kinase Nek2.
Quantity: 100 μg
Research Discipline: Epigenetics and Nuclear Function
Gene ID (Entrez): NP_002488
Target Species: Human, Mouse
Form: Purified
Antigen:
Ser/Thr-protein kinase Nek2
Classification:
Monoclonal
Conjugate:
__
Gene Accession No.:
P51955
Host Species:
Mouse
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
__
Content And Storage:
Stable for one year at 2°C to 8°C from date of receipt.
Isotype:
IgG2b κ
Applications:
Immunocytochemistry, Western Blot
Clone:
5D2.1
Formulation:
Purified mouse monoclonal IgG2bκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols:
NEK2; NEK2A; NLK1
Immunogen:
GST-tagged recombinant protein corresponding to the N-terminal of human Ser/Thr-protein kinase Nek2.
Quantity:
100 μg
Research Discipline:
Epigenetics and Nuclear Function
Gene ID (Entrez):
NP_002488
Target Species:
Human, Mouse
Form:
Purified
Antigen: E3 ubiquitin-protein ligase UHRF1
Classification: Monoclonal
Conjugate: Unconjugated
Gene Accession No.: NP_001104548
Host Species: Mouse
Purification Method: Protein G purified
Regulatory Status: __
Primary or Secondary: Primary
Test Specificity: __
Content And Storage: 2-8°C for one year
Isotype: IgG1 κ
Applications: Immunocytochemistry, Western Blot
Clone: BF18.11
Formulation: Purified mouse monoclonal IgG1κ in buffer containing 0.1MTris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols: Uhrf1, Np95
Immunogen: His-tagged recombinant protein corresponding to mouse E3 ubiquitin-protein ligase UHRF1.
Quantity: 100 μg
Research Discipline: __
Gene ID (Entrez): __
Target Species: Mouse
Form: Purified
Antigen:
E3 ubiquitin-protein ligase UHRF1
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene Accession No.:
NP_001104548
Host Species:
Mouse
Purification Method:
Protein G purified
Regulatory Status:
__
Primary or Secondary:
Primary
Test Specificity:
__
Content And Storage:
2-8°C for one year
Isotype:
IgG1 κ
Applications:
Immunocytochemistry, Western Blot
Clone:
BF18.11
Formulation:
Purified mouse monoclonal IgG1κ in buffer containing 0.1MTris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols:
Uhrf1, Np95
Immunogen:
His-tagged recombinant protein corresponding to mouse E3 ubiquitin-protein ligase UHRF1.
Quantity:
100 μg
Research Discipline:
__
Gene ID (Entrez):
__
Target Species:
Mouse
Form:
Purified