MABE1156MI
MilliporeSigma™ anti-ING4 Clone: BTIM-4,
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | MABE1156MI-Each-of-1 | In Stock | ₹ 40,197.80 |
MABE1156MI - Each of 1
In Stock
Quantity
1
Base Price: ₹ 40,197.80
GST (18%): ₹ 7,235.604
Total Price: ₹ 47,433.404
Antigen
ING4
Classification
Monoclonal
Conjugate
Unconjugated
Gene Accession No.
Q9UNL4
Host Species
Mouse
Purification Method
Protein G purified
Regulatory Status
RUO
Primary or Secondary
Primary
Test Specificity
Clone BTIM-4 reacts with human and murine ING4, but not human ING1, ING2, or ING5 (Byron, S.A., et al. (2012). PLoS One. 7(10):e46823). Expected to react with human ING4 isoform 1 (ING4_v1) and isoform 8 (deltaEx6A). Reactivity toward human ING4 spliced isoform 2 to 7 has not been tested.
Content And Storage
2°C to 8°C for one year from date of shipment
Isotype
IgG1 κ
Applications
Immunocytochemistry, Immunohistochemistry, Western Blot
Clone
BTIM-4
Formulation
Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols
ING4, My036
Immunogen
His-tagged recombinant protein corresponding to the N-terminal half of human ING4.
Quantity
100 μg
Research Discipline
Epigenetics, Nuclear Function
Gene ID (Entrez)
NP_001121054
Target Species
Human, Mouse
Form
Purified
Related Products
Description
- Specifically detects ING4 Clone: BTIM-4 in Human, Mouse samples, and it is validated for Immunocytochemistry, Immunohistochemistry, Western Blotting Inhibitor of growth protein 4 (UniProt Q9UNL4; also known as Brain my036 protein, Candidate tumor suppressor p33 ING1 homolog, p29ING4) is encoded by the ING4 gene (ORF My036; Gene ID 51147) in human
- The inhibitor of growth (ING) family tumor suppressor ING4 is a transcription regulator that exerts its function via chromatin remodeling
- ING4 to targets the trimethylated lysine 4 of histone H3 (H3K4me3) via its conserved plant homeodomain (PHD) finger motif and is shown to associate with the HBO1/JADE histone acetyltransferase (HAT) complex
- ING4 is shown to play a role in many cancer-related cellular processes, including cell proliferation, apoptosis, migration, angiogenesis, contact inhibition, DNA damage response, and hypoxia
- Both gene deletion and reduced ING4 expression are reported in cancers of diverse tissue types, although ING4 knockout by itself does not cause increased spontaneous tumor formation in mice
- Immunohistochemistry analysis of breast cancer tissues shows that 34% of tumors expressed undetectable to low levels of ING4
- In addition, ING4 downregulation inversely correlates with an increase in NF-κB activation and NF-κB-dependent genes expression in primary breast tumors.
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Antigen: ING4
Classification: Monoclonal
Conjugate: Unconjugated
Gene Accession No.: Q9UNL4
Host Species: Mouse
Purification Method: Protein G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Clone BTIM-4 reacts with human and murine ING4, but not human ING1, ING2, or ING5 (Byron, S.A., et al. (2012). PLoS One. 7(10):e46823). Expected to react with human ING4 isoform 1 (ING4_v1) and isoform 8 (deltaEx6A). Reactivity toward human ING4 spliced isoform 2 to 7 has not been tested.
Content And Storage: 2°C to 8°C for one year from date of shipment
Isotype: IgG1 κ
Applications: Immunocytochemistry, Immunohistochemistry, Western Blot
Clone: BTIM-4
Formulation: Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols: ING4, My036
Immunogen: His-tagged recombinant protein corresponding to the N-terminal half of human ING4.
Quantity: 100 μg
Research Discipline: Epigenetics, Nuclear Function
Gene ID (Entrez): NP_001121054
Target Species: Human, Mouse
Form: Purified
Antigen:
ING4
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene Accession No.:
Q9UNL4
Host Species:
Mouse
Purification Method:
Protein G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Clone BTIM-4 reacts with human and murine ING4, but not human ING1, ING2, or ING5 (Byron, S.A., et al. (2012). PLoS One. 7(10):e46823). Expected to react with human ING4 isoform 1 (ING4_v1) and isoform 8 (deltaEx6A). Reactivity toward human ING4 spliced isoform 2 to 7 has not been tested.
Content And Storage:
2°C to 8°C for one year from date of shipment
Isotype:
IgG1 κ
Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot
Clone:
BTIM-4
Formulation:
Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols:
ING4, My036
Immunogen:
His-tagged recombinant protein corresponding to the N-terminal half of human ING4.
Quantity:
100 μg
Research Discipline:
Epigenetics, Nuclear Function
Gene ID (Entrez):
NP_001121054
Target Species:
Human, Mouse
Form:
Purified
Antigen: SPO11
Classification: Monoclonal
Conjugate: Unconjugated
Gene Accession No.: Q9WTK8
Host Species: Mouse
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Clone 180 detected SPO11alpha and SPO11beta in wild-type, but not Spo11-knockout mouse testes lysates by IP-Western blotting.
Content And Storage: Stable for 1 year at 2°-8°C from date of receipt.
Isotype: IgG2a κ
Applications: Immunoprecipitation, Western Blot
Clone: 180
Formulation: Purified mouse IgG2aκ in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Symbols: __
Immunogen: Recombinant mouse SPO11 with N-terminal S-tag and C-terminal His-tag.
Quantity: 100 μg
Research Discipline: Epigenetics & Nuclear Function
Gene ID (Entrez): NP_036176.1
Target Species: Mouse
Form: Purified
Antigen:
SPO11
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene Accession No.:
Q9WTK8
Host Species:
Mouse
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Clone 180 detected SPO11alpha and SPO11beta in wild-type, but not Spo11-knockout mouse testes lysates by IP-Western blotting.
Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.
Isotype:
IgG2a κ
Applications:
Immunoprecipitation, Western Blot
Clone:
180
Formulation:
Purified mouse IgG2aκ in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Symbols:
__
Immunogen:
Recombinant mouse SPO11 with N-terminal S-tag and C-terminal His-tag.
Quantity:
100 μg
Research Discipline:
Epigenetics & Nuclear Function
Gene ID (Entrez):
NP_036176.1
Target Species:
Mouse
Form:
Purified
Antigen: PNKP
Classification: Monoclonal
Conjugate: Unconjugated
Gene Accession No.: Q96T60
Host Species: Mouse
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Clone H101.2 recognizes an epitope in the N-terminal region of PNKP.
Content And Storage: Stable for 1 year at 2°-8°C from date of receipt.
Isotype: IgG1 κ
Applications: Immunoprecipitation, Western Blot
Clone: H101.2
Formulation: Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Symbols: __
Immunogen: His-tagged recombinant full-length human PNKP.
Quantity: 100 μg
Research Discipline: Epigenetics & Nuclear Function
Gene ID (Entrez): NP_009185
Target Species: Bovine
Form: Purified
Antigen:
PNKP
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene Accession No.:
Q96T60
Host Species:
Mouse
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Clone H101.2 recognizes an epitope in the N-terminal region of PNKP.
Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.
Isotype:
IgG1 κ
Applications:
Immunoprecipitation, Western Blot
Clone:
H101.2
Formulation:
Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Symbols:
__
Immunogen:
His-tagged recombinant full-length human PNKP.
Quantity:
100 μg
Research Discipline:
Epigenetics & Nuclear Function
Gene ID (Entrez):
NP_009185
Target Species:
Bovine
Form:
Purified
Antigen: SMARCA4
Classification: Monoclonal
Conjugate: Unconjugated
Gene Accession No.: NP_001122316
Host Species: Mouse
Purification Method: Protein G purified
Regulatory Status: __
Primary or Secondary: Primary
Test Specificity: __
Content And Storage: 2-8°C for one year
Isotype: IgG1 κ
Applications: Immunocytochemistry, Western Blot
Clone: 20C3.2
Formulation: Purified mouse monoclonal IgG1κ in buffer containing 0.1MTris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols: SMARCA4, BAF190A, BRG1, SNF2B, SNF2L4
Immunogen: GST-tagged recombinant protein corresponding to the human SMARCA4.
Quantity: 100 μg
Research Discipline: __
Gene ID (Entrez): __
Target Species: Human, Rat
Form: Purified
Antigen:
SMARCA4
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene Accession No.:
NP_001122316
Host Species:
Mouse
Purification Method:
Protein G purified
Regulatory Status:
__
Primary or Secondary:
Primary
Test Specificity:
__
Content And Storage:
2-8°C for one year
Isotype:
IgG1 κ
Applications:
Immunocytochemistry, Western Blot
Clone:
20C3.2
Formulation:
Purified mouse monoclonal IgG1κ in buffer containing 0.1MTris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols:
SMARCA4, BAF190A, BRG1, SNF2B, SNF2L4
Immunogen:
GST-tagged recombinant protein corresponding to the human SMARCA4.
Quantity:
100 μg
Research Discipline:
__
Gene ID (Entrez):
__
Target Species:
Human, Rat
Form:
Purified