MABE978MI
MilliporeSigma™ anti-Paired box protein Pax-1 Clone: 7F11.2,
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | MABE978MI-Each-of-1 | In Stock | ₹ 42,677.33 |
MABE978MI - Each of 1
In Stock
Quantity
1
Base Price: ₹ 42,677.33
GST (18%): ₹ 7,681.919
Total Price: ₹ 50,359.249
Antigen
Paired box protein Pax-1
Classification
Monoclonal
Conjugate
Unconjugated
Gene Accession No.
P15863
Host Species
Mouse
Purification Method
Protein G purified
Regulatory Status
RUO
Primary or Secondary
Primary
Test Specificity
Reactivity toward spliced isoforms 2 and 3 has not been determined.
Content And Storage
2°C to 8°C for one year from date of shipment
Isotype
IgG2b κ
Applications
Western Blot
Clone
7F11.2
Formulation
Purified mouse monoclonal IgG2bκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols
PAX1, HUP48
Immunogen
GST-tagged recombinant protein corresponding to the N-terminal half of human Paired box protein Pax-1.
Quantity
100 μg
Research Discipline
Epigenetics, Nuclear Function
Gene ID (Entrez)
NP_006183
Target Species
Human
Form
Purified
Related Products
Description
- Specifically detects Paired box protein Pax-1 Clone: 7F11.2 in Human samples, and it is validated for Western Blotting Paired box protein Pax-1 (UniProt P15863; also known as HuP48) is encoded by the PAX1 (also known as HUP48, OFC2) gene (Gene ID 5075) in human
- Pax-1 belongs to the family of transcription factors with conserved DNA-binding paired box domain
- The family of paired box (PAX) genes are divided into subgroup I (PAX1 and PAX9), II (PAX2, PAX5, and PAX8), III (PAX3 and PAX7), and IV (PAX4 and PAX6)
- Pax1 & Pax9 are paralogous genes with overlapping expression and function
- Pax1 is required for the proper development of the ventral structures of the vertebral column and double homozygous mutants of Pax1 and Pax9 result in a dramatic increase in the severity of the vertebral defects
- During the early stages of chondrogenic differentiation, Pax1 induces and transactivates the transcriptional repressor Nk3 homeobox 2 (Nkx3.2) that promotes chondrogenesis of sclerotomal cells, while Pax1 act as a negative regulator during chondrogenic differentiation by antagonizing against Sox9-driven chondrocyte maturation
- Pax1 is downregulated as cartilage formation proceeds and becomes restricted to the mesenchymal condensations that give rise to the anlagen of the intervertebral discs, and to the perichondrium surrounding the cartilaginous vertebral bodies.
Compare Similar Items
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Antigen: Paired box protein Pax-1
Classification: Monoclonal
Conjugate: Unconjugated
Gene Accession No.: P15863
Host Species: Mouse
Purification Method: Protein G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Reactivity toward spliced isoforms 2 and 3 has not been determined.
Content And Storage: 2°C to 8°C for one year from date of shipment
Isotype: IgG2b κ
Applications: Western Blot
Clone: 7F11.2
Formulation: Purified mouse monoclonal IgG2bκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols: PAX1, HUP48
Immunogen: GST-tagged recombinant protein corresponding to the N-terminal half of human Paired box protein Pax-1.
Quantity: 100 μg
Research Discipline: Epigenetics, Nuclear Function
Gene ID (Entrez): NP_006183
Target Species: Human
Form: Purified
Antigen:
Paired box protein Pax-1
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene Accession No.:
P15863
Host Species:
Mouse
Purification Method:
Protein G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Reactivity toward spliced isoforms 2 and 3 has not been determined.
Content And Storage:
2°C to 8°C for one year from date of shipment
Isotype:
IgG2b κ
Applications:
Western Blot
Clone:
7F11.2
Formulation:
Purified mouse monoclonal IgG2bκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols:
PAX1, HUP48
Immunogen:
GST-tagged recombinant protein corresponding to the N-terminal half of human Paired box protein Pax-1.
Quantity:
100 μg
Research Discipline:
Epigenetics, Nuclear Function
Gene ID (Entrez):
NP_006183
Target Species:
Human
Form:
Purified
Antigen: Fox1
Classification: Monoclonal
Conjugate: __
Gene Accession No.: Q9JJ43
Host Species: Mouse
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: __
Content And Storage: Stable for one year at 2°C to 8°C from date of receipt.
Isotype: IgG2a κ
Applications: Immunocytochemistry, Immunohistochemistry, Immunoprecipitation, Western Blot
Clone: 1D10
Formulation: Purified mouse monoclonal IgG2aκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols: Rbfox1; A2bp; A2bp1; Fox1; MNCb-3035
Immunogen: GST-tagged recombinant protein corresponding to mouse Fox1.
Quantity: 100 μg
Research Discipline: Epigenetics and Nuclear Function
Gene ID (Entrez): NP_067452
Target Species: Mouse
Form: Purified
Antigen:
Fox1
Classification:
Monoclonal
Conjugate:
__
Gene Accession No.:
Q9JJ43
Host Species:
Mouse
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
__
Content And Storage:
Stable for one year at 2°C to 8°C from date of receipt.
Isotype:
IgG2a κ
Applications:
Immunocytochemistry, Immunohistochemistry, Immunoprecipitation, Western Blot
Clone:
1D10
Formulation:
Purified mouse monoclonal IgG2aκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols:
Rbfox1; A2bp; A2bp1; Fox1; MNCb-3035
Immunogen:
GST-tagged recombinant protein corresponding to mouse Fox1.
Quantity:
100 μg
Research Discipline:
Epigenetics and Nuclear Function
Gene ID (Entrez):
NP_067452
Target Species:
Mouse
Form:
Purified
Antigen: Homeobox protein CDX-2
Classification: Monoclonal
Conjugate: __
Gene Accession No.: Q99626
Host Species: Mouse
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: __
Content And Storage: Stable for one year at 2°C to 8°C from date of receipt.
Isotype: IgG1 κ
Applications: Immunohistochemistry (Paraffin), Western Blot
Clone: 7D9.1
Formulation: Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols: CDX2; CDX3
Immunogen: GST-tagged recombinant protein corresponding to human Homeobox protein CDX-2.
Quantity: 100 μg
Research Discipline: Epigenetics and Nuclear Function
Gene ID (Entrez): NP_001256
Target Species: Human
Form: Purified
Antigen:
Homeobox protein CDX-2
Classification:
Monoclonal
Conjugate:
__
Gene Accession No.:
Q99626
Host Species:
Mouse
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
__
Content And Storage:
Stable for one year at 2°C to 8°C from date of receipt.
Isotype:
IgG1 κ
Applications:
Immunohistochemistry (Paraffin), Western Blot
Clone:
7D9.1
Formulation:
Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols:
CDX2; CDX3
Immunogen:
GST-tagged recombinant protein corresponding to human Homeobox protein CDX-2.
Quantity:
100 μg
Research Discipline:
Epigenetics and Nuclear Function
Gene ID (Entrez):
NP_001256
Target Species:
Human
Form:
Purified
Antigen: MSL-2
Classification: Monoclonal
Conjugate: Unconjugated
Gene Accession No.: Q9HCI7
Host Species: Mouse
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Expected to react with both spliced isoforms of human MSL2 reported by UniProt (Q9HCI7).
Content And Storage: Stable for 1 year at 2°-8°C from date of receipt.
Isotype: IgG1 κ
Applications: Western Blot
Clone: 10C3.1
Formulation: Purified mouse monoclonal IgG1κ in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Symbols: __
Immunogen: GST-tagged recombinant human MSL-2 C-terminal fragment.
Quantity: 100 μg
Research Discipline: Epigenetics & Nuclear Function
Gene ID (Entrez): NP_060603
Target Species: Human
Form: Purified
Antigen:
MSL-2
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene Accession No.:
Q9HCI7
Host Species:
Mouse
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Expected to react with both spliced isoforms of human MSL2 reported by UniProt (Q9HCI7).
Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.
Isotype:
IgG1 κ
Applications:
Western Blot
Clone:
10C3.1
Formulation:
Purified mouse monoclonal IgG1κ in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Symbols:
__
Immunogen:
GST-tagged recombinant human MSL-2 C-terminal fragment.
Quantity:
100 μg
Research Discipline:
Epigenetics & Nuclear Function
Gene ID (Entrez):
NP_060603
Target Species:
Human
Form:
Purified