MABE948MI
MilliporeSigma™ anti-BRE1-A (RNF20) Clone: 8A4.2,
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | MABE948MI-Each-of-1 | In Stock | ₹ 40,197.80 |
MABE948MI - Each of 1
In Stock
Quantity
1
Base Price: ₹ 40,197.80
GST (18%): ₹ 7,235.604
Total Price: ₹ 47,433.404
Antigen
BRE1-A (RNF20)
Classification
Monoclonal
Conjugate
Unconjugated
Gene Accession No.
Q5VTR2
Host Species
Mouse
Purification Method
Protein G purified
Regulatory Status
RUO
Primary or Secondary
Primary
Target Species
Human
Form
Purified
Applications
Western Blot
Clone
8A4.2
Formulation
Purified mouse monoclonal IgG2aκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols
RNF20, BRE1, BRE1A
Immunogen
GST-tagged recombinant protein corresponding to the third coiled-coil region of human BRE1-A (RNF20).
Quantity
100 μg
Research Discipline
Epigenetics, Nuclear Function
Gene ID (Entrez)
NP_062538
Content And Storage
2°C to 8°C for one year from date of shipment
Isotype
IgG2a κ
Related Products
Description
- Specifically detects BRE1-A (RNF20) Clone: 8A4.2 in Human samples, and it is validated for Western Blotting E3 ubiquitin-protein ligase BRE1A (UniProt Q5VTR2; also known as BRE1 E3 ubiquitin ligase homolog, BRE1-A, hBRE1, Homolog of S
- cerevisiae BRE1, RING finger protein 20) is encoded by the RNF20 (also known as BRE1, BRE1A) gene (Gene ID 56254) in human
- BRE1A (RNF20) is a RING finger domain-containing protein originally identified as the E3 uqibiquitin ligase that catalyzes histone H2B Lys120 monoubiquitination in yeast
- The histone chaperone FACT is reported to mediate RNF20 recruitment for chromatin remodeling to initiate homologous recombination repair (HRR)
- RNF20 is also shown to negatively regulate hepatic fatty acid metabolism by targeting SREBP1c for ubiquitination and subsequent proteasomal degradation
- In addition, RNF20 is shown to mediated the polyubiquitination of ErbB3-binding protein 1 (Ebp1) and Transcription factor activator protein 2α (AP-2α)
- AP-2α functions as a negative regulator of adipogenesis by suppressing the transcription of CCAAT/enhancer binding protein (C/EBPα)
- Overexpression of RNF20 in 3T3-L1 cells results in a down-regulation of endogenous AP-2α and a concomitant transcriptional upregulation of C/EBPα.
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Antigen: BRE1-A (RNF20)
Classification: Monoclonal
Conjugate: Unconjugated
Gene Accession No.: Q5VTR2
Host Species: Mouse
Purification Method: Protein G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human
Form: Purified
Applications: Western Blot
Clone: 8A4.2
Formulation: Purified mouse monoclonal IgG2aκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols: RNF20, BRE1, BRE1A
Immunogen: GST-tagged recombinant protein corresponding to the third coiled-coil region of human BRE1-A (RNF20).
Quantity: 100 μg
Research Discipline: Epigenetics, Nuclear Function
Gene ID (Entrez): NP_062538
Content And Storage: 2°C to 8°C for one year from date of shipment
Isotype: IgG2a κ
Antigen:
BRE1-A (RNF20)
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene Accession No.:
Q5VTR2
Host Species:
Mouse
Purification Method:
Protein G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Human
Form:
Purified
Applications:
Western Blot
Clone:
8A4.2
Formulation:
Purified mouse monoclonal IgG2aκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols:
RNF20, BRE1, BRE1A
Immunogen:
GST-tagged recombinant protein corresponding to the third coiled-coil region of human BRE1-A (RNF20).
Quantity:
100 μg
Research Discipline:
Epigenetics, Nuclear Function
Gene ID (Entrez):
NP_062538
Content And Storage:
2°C to 8°C for one year from date of shipment
Isotype:
IgG2a κ
Antigen: E3 Ubiquitin Ligase BRE1B
Classification: Monoclonal
Conjugate: Unconjugated
Gene Accession No.: O75150
Host Species: Mouse
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human
Form: Purified
Applications: Western Blot
Clone: 4H8.1
Formulation: Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Symbols: __
Immunogen: GST-tagged recombinant internal fragment from the C-terminal half of human BRE1B .
Quantity: 100 μL
Research Discipline: Epigenetics & Nuclear Function
Gene ID (Entrez): NP_001193962
Content And Storage: Stable for 1 year at 2°-8°C from date of receipt.
Isotype: IgG1 κ
Antigen:
E3 Ubiquitin Ligase BRE1B
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene Accession No.:
O75150
Host Species:
Mouse
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Human
Form:
Purified
Applications:
Western Blot
Clone:
4H8.1
Formulation:
Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Symbols:
__
Immunogen:
GST-tagged recombinant internal fragment from the C-terminal half of human BRE1B .
Quantity:
100 μL
Research Discipline:
Epigenetics & Nuclear Function
Gene ID (Entrez):
NP_001193962
Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.
Isotype:
IgG1 κ
Antigen: Histone H3.3
Classification: Monoclonal
Conjugate: Unconjugated
Gene Accession No.: NP_002098
Host Species: Rat
Purification Method: Protein G purified
Regulatory Status: __
Primary or Secondary: Primary
Target Species: Canine, Human, Monkey, Mouse
Form: Purified
Applications: Western Blot
Clone: 6C4A3
Formulation: Purified rat monoclonal IgG2aκ in buffer containing 0.1MTris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols: H3F3B, H3.3B
Immunogen: KLH-conjugated linear peptide corresponding to human Histone H3.3.
Quantity: 100 μg
Research Discipline: __
Gene ID (Entrez): __
Content And Storage: 2-8°C for one year
Isotype: IgG2a κ
Antigen:
Histone H3.3
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene Accession No.:
NP_002098
Host Species:
Rat
Purification Method:
Protein G purified
Regulatory Status:
__
Primary or Secondary:
Primary
Target Species:
Canine, Human, Monkey, Mouse
Form:
Purified
Applications:
Western Blot
Clone:
6C4A3
Formulation:
Purified rat monoclonal IgG2aκ in buffer containing 0.1MTris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols:
H3F3B, H3.3B
Immunogen:
KLH-conjugated linear peptide corresponding to human Histone H3.3.
Quantity:
100 μg
Research Discipline:
__
Gene ID (Entrez):
__
Content And Storage:
2-8°C for one year
Isotype:
IgG2a κ
Antigen: Histone H3.1
Classification: Monoclonal
Conjugate: Unconjugated
Gene Accession No.: NP_003520
Host Species: Rat
Purification Method: Protein G purified
Regulatory Status: __
Primary or Secondary: Primary
Target Species: Human, Mouse
Form: Purified
Applications: ChIP Assay, Immunocytochemistry, Immunoprecipitation, Western Blot
Clone: 1D4F2
Formulation: Purified rat monoclonal in buffer containing 0.1MTris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols: HIST1H3A, H3FA, HIST1H3B, H3FL, HIST1H3C, H3FC, HIST1H3D, H3FB, HIST1H3E, H3FD, HIST1H3F, H3FI, HIST1H3G, H3FH, HIST1H3H, H3FK, HIST1H3I, H3FF, HIST1H3J, H3FJ
Immunogen: KLH-conjugated linear peptide corresponding to human Histone H3.1.
Quantity: 100 μg
Research Discipline: __
Gene ID (Entrez): __
Content And Storage: 2-8°C for one year
Isotype: __
Antigen:
Histone H3.1
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene Accession No.:
NP_003520
Host Species:
Rat
Purification Method:
Protein G purified
Regulatory Status:
__
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Form:
Purified
Applications:
ChIP Assay, Immunocytochemistry, Immunoprecipitation, Western Blot
Clone:
1D4F2
Formulation:
Purified rat monoclonal in buffer containing 0.1MTris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols:
HIST1H3A, H3FA, HIST1H3B, H3FL, HIST1H3C, H3FC, HIST1H3D, H3FB, HIST1H3E, H3FD, HIST1H3F, H3FI, HIST1H3G, H3FH, HIST1H3H, H3FK, HIST1H3I, H3FF, HIST1H3J, H3FJ
Immunogen:
KLH-conjugated linear peptide corresponding to human Histone H3.1.
Quantity:
100 μg
Research Discipline:
__
Gene ID (Entrez):
__
Content And Storage:
2-8°C for one year
Isotype:
__