MABE949MI
MilliporeSigma™ E3 Ubiquitin Ligase BRE1B, Mouse, Unlabeled, Clone: 4H8.1,
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | MABE949MI-Each-of-1 | In Stock | ₹ 40,197.80 |
MABE949MI - Each of 1
In Stock
Quantity
1
Base Price: ₹ 40,197.80
GST (18%): ₹ 7,235.604
Total Price: ₹ 47,433.404
Antigen
E3 Ubiquitin Ligase BRE1B
Classification
Monoclonal
Concentration
Please refer to lot specific datasheet.
Formulation
Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.
O75150
Immunogen
GST-tagged recombinant internal fragment from the C-terminal half of human BRE1B .
Quantity
100 μL
Research Discipline
Epigenetics & Nuclear Function
Gene ID (Entrez)
NP_001193962
Target Species
Human
Form
Purified
Applications
Western Blot
Clone
4H8.1
Conjugate
Unconjugated
Gene
RNF40, BRE1B, KIAA0661
Host Species
Mouse
Purification Method
Protein G Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Test Specificity
Clone 4H8.1 epitope region is present in all three spliced isoforms of human BRE1B reported by UniProt (O75150).
Content And Storage
Stable for 1 year at 2°-8°C from date of receipt.
Isotype
IgG1 κ
Related Products
Description
- E3 ubiquitin-protein ligase BRE1B (UniProt O75150; also known as 95kDa retinoblastoma-associated protein, BRE1-B, RBP95, RING finger protein 40, Syntaxin-1-interacting RING finger protein, Protein staring) is encoded by the RNF40 (also known as BRE1B, KIAA0661) gene (Gene ID 9810) in human
- Proteini ubiquitination is mediated by ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s), and ubiquitin ligases (E3s)
- There exist RING finger-type (really interesting new gene), HECT-type (homologous to E6-AP C-terminus), and U-box type of E3 ligases
- RING finger ubiquitin ligase members can function as monomers, dimers, or multi-subunit complexes
- The RNF20-RNF40 heterodimer mediates the ubiquitination of histone H2B at Lysine 120, an event that plays an important role in decompacting chromatin fiber to allow transcription elongation, in stem cell differentiation, as well as in DNA double-strand breaks (DSBs) repair via the homologous recombination (HR) and nonhomologous end-joining (NHEJ) pathways
- Human RNF40 is a 1001-amino acid protein containing a RING-type zinc finger in its C-terminal region (a.a
- 948-987) that mediates its interaction with RNF20.
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Antigen: E3 Ubiquitin Ligase BRE1B
Classification: Monoclonal
Concentration: Please refer to lot specific datasheet.
Formulation: Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.: O75150
Immunogen: GST-tagged recombinant internal fragment from the C-terminal half of human BRE1B .
Quantity: 100 μL
Research Discipline: Epigenetics & Nuclear Function
Gene ID (Entrez): NP_001193962
Target Species: Human
Form: Purified
Applications: Western Blot
Clone: 4H8.1
Conjugate: Unconjugated
Gene: RNF40, BRE1B, KIAA0661
Host Species: Mouse
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Clone 4H8.1 epitope region is present in all three spliced isoforms of human BRE1B reported by UniProt (O75150).
Content And Storage: Stable for 1 year at 2°-8°C from date of receipt.
Isotype: IgG1 κ
Antigen:
E3 Ubiquitin Ligase BRE1B
Classification:
Monoclonal
Concentration:
Please refer to lot specific datasheet.
Formulation:
Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.:
O75150
Immunogen:
GST-tagged recombinant internal fragment from the C-terminal half of human BRE1B .
Quantity:
100 μL
Research Discipline:
Epigenetics & Nuclear Function
Gene ID (Entrez):
NP_001193962
Target Species:
Human
Form:
Purified
Applications:
Western Blot
Clone:
4H8.1
Conjugate:
Unconjugated
Gene:
RNF40, BRE1B, KIAA0661
Host Species:
Mouse
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Clone 4H8.1 epitope region is present in all three spliced isoforms of human BRE1B reported by UniProt (O75150).
Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.
Isotype:
IgG1 κ
Antigen: Histone H3.3
Classification: Monoclonal
Concentration: 1mg/mL
Formulation: Purified rat monoclonal IgG2aκ in buffer containing 0.1MTris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Accession No.: NP_002098
Immunogen: KLH-conjugated linear peptide corresponding to human Histone H3.3.
Quantity: 100 μg
Research Discipline: __
Gene ID (Entrez): __
Target Species: Canine, Human, Monkey, Mouse
Form: Purified
Applications: Western Blot
Clone: 6C4A3
Conjugate: Unconjugated
Gene: __
Host Species: Rat
Purification Method: Protein G purified
Regulatory Status: __
Primary or Secondary: Primary
Test Specificity: __
Content And Storage: 2-8°C for one year
Isotype: IgG2a κ
Antigen:
Histone H3.3
Classification:
Monoclonal
Concentration:
1mg/mL
Formulation:
Purified rat monoclonal IgG2aκ in buffer containing 0.1MTris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Accession No.:
NP_002098
Immunogen:
KLH-conjugated linear peptide corresponding to human Histone H3.3.
Quantity:
100 μg
Research Discipline:
__
Gene ID (Entrez):
__
Target Species:
Canine, Human, Monkey, Mouse
Form:
Purified
Applications:
Western Blot
Clone:
6C4A3
Conjugate:
Unconjugated
Gene:
__
Host Species:
Rat
Purification Method:
Protein G purified
Regulatory Status:
__
Primary or Secondary:
Primary
Test Specificity:
__
Content And Storage:
2-8°C for one year
Isotype:
IgG2a κ
Antigen: Histone H3.1
Classification: Monoclonal
Concentration: 1mg/mL
Formulation: Purified rat monoclonal in buffer containing 0.1MTris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Accession No.: NP_003520
Immunogen: KLH-conjugated linear peptide corresponding to human Histone H3.1.
Quantity: 100 μg
Research Discipline: __
Gene ID (Entrez): __
Target Species: Human, Mouse
Form: Purified
Applications: ChIP Assay, Immunocytochemistry, Immunoprecipitation, Western Blot
Clone: 1D4F2
Conjugate: Unconjugated
Gene: __
Host Species: Rat
Purification Method: Protein G purified
Regulatory Status: __
Primary or Secondary: Primary
Test Specificity: __
Content And Storage: 2-8°C for one year
Isotype: __
Antigen:
Histone H3.1
Classification:
Monoclonal
Concentration:
1mg/mL
Formulation:
Purified rat monoclonal in buffer containing 0.1MTris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Accession No.:
NP_003520
Immunogen:
KLH-conjugated linear peptide corresponding to human Histone H3.1.
Quantity:
100 μg
Research Discipline:
__
Gene ID (Entrez):
__
Target Species:
Human, Mouse
Form:
Purified
Applications:
ChIP Assay, Immunocytochemistry, Immunoprecipitation, Western Blot
Clone:
1D4F2
Conjugate:
Unconjugated
Gene:
__
Host Species:
Rat
Purification Method:
Protein G purified
Regulatory Status:
__
Primary or Secondary:
Primary
Test Specificity:
__
Content And Storage:
2-8°C for one year
Isotype:
__
Antigen: phospho RNA Pol II (Ser2)
Classification: Monoclonal
Concentration: __
Formulation: Purified rat monoclonal IgG2aκ in buffer containing 0.1MTris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Accession No.: NP_000928
Immunogen: KLH-conjugated linear peptide corresponding to human RNA Pol II phosphorylated at Ser2.
Quantity: 100 μg
Research Discipline: __
Gene ID (Entrez): __
Target Species: Canine, Human, Monkey, Mouse, Rat
Form: Purified
Applications: ChIP Assay, ELISA, Immunocytochemistry, Western Blot
Clone: 3E7C7
Conjugate: Unconjugated
Gene: __
Host Species: Rat
Purification Method: Protein G purified
Regulatory Status: __
Primary or Secondary: Primary
Test Specificity: __
Content And Storage: 2-8°C for one year
Isotype: IgG2a κ
Antigen:
phospho RNA Pol II (Ser2)
Classification:
Monoclonal
Concentration:
__
Formulation:
Purified rat monoclonal IgG2aκ in buffer containing 0.1MTris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Accession No.:
NP_000928
Immunogen:
KLH-conjugated linear peptide corresponding to human RNA Pol II phosphorylated at Ser2.
Quantity:
100 μg
Research Discipline:
__
Gene ID (Entrez):
__
Target Species:
Canine, Human, Monkey, Mouse, Rat
Form:
Purified
Applications:
ChIP Assay, ELISA, Immunocytochemistry, Western Blot
Clone:
3E7C7
Conjugate:
Unconjugated
Gene:
__
Host Species:
Rat
Purification Method:
Protein G purified
Regulatory Status:
__
Primary or Secondary:
Primary
Test Specificity:
__
Content And Storage:
2-8°C for one year
Isotype:
IgG2a κ