MABS1190MI
MilliporeSigma™ Glucokinase/GCK, Mouse, Unlabeled, Clone: 9G1.2,
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | MABS1190MI-Each-of-1 | In Stock | ₹ 38,734.72 |
MABS1190MI - Each of 1
In Stock
Quantity
1
Base Price: ₹ 38,734.72
GST (18%): ₹ 6,972.25
Total Price: ₹ 45,706.97
Antigen
Glucokinase/GCK
Classification
Monoclonal
Concentration
Please refer to lot specific datasheet.
Formulation
Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.
P35557
Immunogen
GST-tagged recombinant internal fragment from the C-terminal half of human Glucokinase/GCK.
Quantity
100 μg
Research Discipline
Signaling
Gene ID (Entrez)
NP_000153
Target Species
Human
Form
Purified
Applications
Western Blot
Clone
9G1.2
Conjugate
Unconjugated
Gene
GCK, HHF3, MODY2
Host Species
Mouse
Purification Method
Protein G Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Test Specificity
Clone 9G1.2 recognizes an epitope present in all three spliced isoforms of human Glucokinase/GCK reported by UniProt (P35557).
Content And Storage
Stable for 1 year at 2°-8°C from date of receipt.
Isotype
IgG1 κ
Related Products
Description
- Description Glucokinase (EC 2.7.1.2; UniProt P35557; also known as GK, Hexokinase-4, Hexokinase-D, Hexokinase type IV, HK IV, HK4) is encoded by the GCK (also known as HHF3, MODY2) gene (Gene ID 2645) in human
- Glucokinase/GK functions as the body's primary glucose sensor by catalyzing the ATP-dependent phosphorylation of glucose to glucose-6-phosphate, the rate-limiting step of glucose metabolism in human pancreas and liver
- GK activity is regulated rapidly in response to the elevated blood glucose after feeding, whereby a change in GK conformation causes a dissociation of the nuclear GK-glucokinase regulatory protein (GKRP) complex, allowing GK translocation to the cytoplasm in an activated state
- In mammals, there exist four types of hexokinases, HK1, HK2, and HK3 have high affinity for glucose, while GK (also known as HK4) has low affinity for glucose and its expression is restricted to the pancreas and liver
- GCK gene mutations cause Maturity-onset diabetes of the young 2 (MODY2) and Familial hyperinsulinemic hypoglycemia 3 (HHF3).
Compare Similar Items
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Antigen: Glucokinase/GCK
Classification: Monoclonal
Concentration: Please refer to lot specific datasheet.
Formulation: Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.: P35557
Immunogen: GST-tagged recombinant internal fragment from the C-terminal half of human Glucokinase/GCK.
Quantity: 100 μg
Research Discipline: Signaling
Gene ID (Entrez): NP_000153
Target Species: Human
Form: Purified
Applications: Western Blot
Clone: 9G1.2
Conjugate: Unconjugated
Gene: GCK, HHF3, MODY2
Host Species: Mouse
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Clone 9G1.2 recognizes an epitope present in all three spliced isoforms of human Glucokinase/GCK reported by UniProt (P35557).
Content And Storage: Stable for 1 year at 2°-8°C from date of receipt.
Isotype: IgG1 κ
Antigen:
Glucokinase/GCK
Classification:
Monoclonal
Concentration:
Please refer to lot specific datasheet.
Formulation:
Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.:
P35557
Immunogen:
GST-tagged recombinant internal fragment from the C-terminal half of human Glucokinase/GCK.
Quantity:
100 μg
Research Discipline:
Signaling
Gene ID (Entrez):
NP_000153
Target Species:
Human
Form:
Purified
Applications:
Western Blot
Clone:
9G1.2
Conjugate:
Unconjugated
Gene:
GCK, HHF3, MODY2
Host Species:
Mouse
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Clone 9G1.2 recognizes an epitope present in all three spliced isoforms of human Glucokinase/GCK reported by UniProt (P35557).
Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.
Isotype:
IgG1 κ
Antigen: ABCB11
Classification: Monoclonal
Concentration: __
Formulation: Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Accession No.: O95342
Immunogen: GST-tagged recombinant fragment derived from the fourth cytoplasmic domain of human ABCB11.
Quantity: 100 μg
Research Discipline: Signaling
Gene ID (Entrez): NP_003733
Target Species: Human
Form: Purified
Applications: Immunohistochemistry (Paraffin), Western Blot
Clone: 10D4.1
Conjugate: __
Gene: __
Host Species: Mouse
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: __
Content And Storage: Stable for one year at 2°C to 8°C from date of receipt.
Isotype: IgG1 κ
Antigen:
ABCB11
Classification:
Monoclonal
Concentration:
__
Formulation:
Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Accession No.:
O95342
Immunogen:
GST-tagged recombinant fragment derived from the fourth cytoplasmic domain of human ABCB11.
Quantity:
100 μg
Research Discipline:
Signaling
Gene ID (Entrez):
NP_003733
Target Species:
Human
Form:
Purified
Applications:
Immunohistochemistry (Paraffin), Western Blot
Clone:
10D4.1
Conjugate:
__
Gene:
__
Host Species:
Mouse
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
__
Content And Storage:
Stable for one year at 2°C to 8°C from date of receipt.
Isotype:
IgG1 κ
Antigen: SSH1
Classification: Monoclonal
Concentration: __
Formulation: Purified mouse monoclonal IgG2aκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Accession No.: Q8WYL5
Immunogen: GST-tagged recombinant protein corresponding to an internal sequence of human SSH1.
Quantity: 100 μg
Research Discipline: Cell Structure
Gene ID (Entrez): NP_061857
Target Species: Human
Form: Purified
Applications: Western Blot
Clone: 12C6.1
Conjugate: __
Gene: __
Host Species: Mouse
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: __
Content And Storage: Stable for one year at 2°C to 8°C from date of receipt.
Isotype: IgG2a κ
Antigen:
SSH1
Classification:
Monoclonal
Concentration:
__
Formulation:
Purified mouse monoclonal IgG2aκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Accession No.:
Q8WYL5
Immunogen:
GST-tagged recombinant protein corresponding to an internal sequence of human SSH1.
Quantity:
100 μg
Research Discipline:
Cell Structure
Gene ID (Entrez):
NP_061857
Target Species:
Human
Form:
Purified
Applications:
Western Blot
Clone:
12C6.1
Conjugate:
__
Gene:
__
Host Species:
Mouse
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
__
Content And Storage:
Stable for one year at 2°C to 8°C from date of receipt.
Isotype:
IgG2a κ
Antigen: SENP1
Classification: Monoclonal
Concentration: Please refer to lot specific datasheet.
Formulation: Mouse monoclonal IgG2bλ hybridoma culture supernatant with 0.05% Sodium Azide.
Gene Accession No.: Q9P0U3
Immunogen: GST-tagged recombinant fragment from the C-terminal half of human SENP1.
Quantity: 100 μL
Research Discipline: Signaling
Gene ID (Entrez): NP_001254523
Target Species: Human
Form: Culture Supernatant
Applications: Western Blot
Clone: 8B6.1
Conjugate: Unconjugated
Gene: SENP1
Host Species: Mouse
Purification Method: Unpurified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Expected to react with both spliced isoforms of human SENP1 reported by UniProt (Q9P0U3).
Content And Storage: Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Isotype: IgG2b λ
Antigen:
SENP1
Classification:
Monoclonal
Concentration:
Please refer to lot specific datasheet.
Formulation:
Mouse monoclonal IgG2bλ hybridoma culture supernatant with 0.05% Sodium Azide.
Gene Accession No.:
Q9P0U3
Immunogen:
GST-tagged recombinant fragment from the C-terminal half of human SENP1.
Quantity:
100 μL
Research Discipline:
Signaling
Gene ID (Entrez):
NP_001254523
Target Species:
Human
Form:
Culture Supernatant
Applications:
Western Blot
Clone:
8B6.1
Conjugate:
Unconjugated
Gene:
SENP1
Host Species:
Mouse
Purification Method:
Unpurified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Expected to react with both spliced isoforms of human SENP1 reported by UniProt (Q9P0U3).
Content And Storage:
Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Isotype:
IgG2b λ