MABE985MI

MilliporeSigma™ Mouse anti-Fox1, Clone: 1D10,

Manufacturer: MilliporeSigma™

Select a Size

Pack Size SKU Availability Price
Each of 1 MABE985MI-Each-of-1 In Stock ₹ 34,965.81

MABE985MI - Each of 1

₹ 34,965.81

In Stock

Quantity

1

Base Price: ₹ 34,965.81

GST (18%): ₹ 6,293.846

Total Price: ₹ 41,259.656

Antigen

Fox1

Classification

Monoclonal

Formulation

Purified mouse monoclonal IgG2aκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.

Gene Symbols

Rbfox1; A2bp; A2bp1; Fox1; MNCb-3035

Immunogen

GST-tagged recombinant protein corresponding to mouse Fox1.

Quantity

100 μg

Research Discipline

Epigenetics and Nuclear Function

Gene ID (Entrez)

NP_067452

Content And Storage

Stable for one year at 2°C to 8°C from date of receipt.

Isotype

IgG2a κ

Applications

Immunocytochemistry, Immunohistochemistry, Immunoprecipitation, Western Blot

Clone

1D10

Gene Accession No.

Q9JJ43

Host Species

Mouse

Purification Method

Protein G Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Target Species

Mouse

Form

Purified

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Description

  • Specifically detects Fox1 clone: 1D10 in Mouse samples, and it is validated for Immunocytochemistry, Immunohistochemistry, Immunoprecipitation, Western Blotting RNA binding protein fox-1 homolog 1 (UniProt Q9JJ43; also known as Ataxin-2-binding protein 1, Fox-1 homolog A, Hexaribonucleotide binding protein 1) is encoded by the Rbfox1 (also known as A2bp, A2bp1, Fox-1, Hrnbp1) gene (ORF MNCb-3035; Gene ID 268859) in murine species
  • The RNA-binding Fox (Rbfox) family of splicing factors is comprised of three members, Rbfox1 (Fox-1 or A2BP1), Rbfox2 (Fox-2 or RBM9), and Rbfox3 (Fox-3, HRNBP3 or NeuN)
  • Rbfox proteins regulate splicing of many neuronal transcripts (pre-mRNAs) by binding the sequence (U)GCAUG in introns flanking alternative exons
  • A (U)GCAUG motif that lies downstream of the alternative exon generally promotes Rbfox-dependent exon inclusion, whereas an upstream motif will usually repress exon inclusion
  • Rbfox1 transcript itself is subjected to alternative splicing in response to chronic cell depolarization
  • This results in the increased expression of the nuclear, splicing-active Rbfox1 isoform, which in turn leads to increased splicing of Rbfox1 target transcripts of proteins, including N-methyl D-aspartate (NMDA) receptor 1 (Grin1) and a calcium ATPase (Atp2b1), that play important roles in neuronal excitation and calcium homeostasis.

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MilliporeSigma™

MABE985MI

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Antigen:
Fox1

Classification:
Monoclonal

Formulation:
Purified mouse monoclonal IgG2aκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.

Gene Symbols:
Rbfox1; A2bp; A2bp1; Fox1; MNCb-3035

Immunogen:
GST-tagged recombinant protein corresponding to mouse Fox1.

Quantity:
100 μg

Research Discipline:
Epigenetics and Nuclear Function

Gene ID (Entrez):
NP_067452

Content And Storage:
Stable for one year at 2°C to 8°C from date of receipt.

Isotype:
IgG2a κ

Applications:
Immunocytochemistry, Immunohistochemistry, Immunoprecipitation, Western Blot

Clone:
1D10

Gene Accession No.:
Q9JJ43

Host Species:
Mouse

Purification Method:
Protein G Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Mouse

Form:
Purified

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MABE988MI

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Antigen:
Homeobox protein CDX-2

Classification:
Monoclonal

Formulation:
Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.

Gene Symbols:
CDX2; CDX3

Immunogen:
GST-tagged recombinant protein corresponding to human Homeobox protein CDX-2.

Quantity:
100 μg

Research Discipline:
Epigenetics and Nuclear Function

Gene ID (Entrez):
NP_001256

Content And Storage:
Stable for one year at 2°C to 8°C from date of receipt.

Isotype:
IgG1 κ

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
7D9.1

Gene Accession No.:
Q99626

Host Species:
Mouse

Purification Method:
Protein G Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human

Form:
Purified

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Antigen:
MSL-2

Classification:
Monoclonal

Formulation:
Purified mouse monoclonal IgG1κ in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.

Gene Symbols:
__

Immunogen:
GST-tagged recombinant human MSL-2 C-terminal fragment.

Quantity:
100 μg

Research Discipline:
Epigenetics & Nuclear Function

Gene ID (Entrez):
NP_060603

Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.

Isotype:
IgG1 κ

Applications:
Western Blot

Clone:
10C3.1

Gene Accession No.:
Q9HCI7

Host Species:
Mouse

Purification Method:
Protein G Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human

Form:
Purified

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Antigen:
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Classification:
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Immunogen:
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Content And Storage:
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Isotype:
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Applications:
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Clone:
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Gene Accession No.:
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Host Species:
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Purification Method:
__

Regulatory Status:
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Primary or Secondary:
__

Target Species:
__

Form:
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