MABC1032MI

MilliporeSigma™ anti-Pro-Atrial Natriuretic Peptide Clone: 11E3.9,

Manufacturer: MilliporeSigma™

Select a Size

Pack Size SKU Availability Price
Each of 1 MABC1032MI-Each-of-1 In Stock ₹ 48,852.19

MABC1032MI - Each of 1

₹ 48,852.19

In Stock

Quantity

1

Base Price: ₹ 48,852.19

GST (18%): ₹ 8,793.394

Total Price: ₹ 57,645.584

Antigen

Pro-Atrial Natriuretic Peptide

Classification

Monoclonal

Conjugate

Unconjugated

Gene Accession No.

P01160

Host Species

Mouse

Purification Method

Protein G purified

Regulatory Status

RUO

Primary or Secondary

Primary

Test Specificity

Expected to react with both prepro- and pro-atrial natriuretic peptide (ANP), but not mature ANP (a.a. 124-151 of prepro sequence).

Content And Storage

2°C to 8°C for one year from date of shipment

Isotype

IgG1 κ

Applications

Immunohistochemistry (Paraffin), Western Blot

Clone

11E3.9

Formulation

Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.

Gene Symbols

NPPA, ANP, PND

Immunogen

His-tagged recombinant protein corresponding to human Pro-Atrial Natriuretic Peptide.

Quantity

100 μg

Research Discipline

Apoptosis, Cancer

Gene ID (Entrez)

NP_006163

Target Species

Human, Rat

Form

Purified

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Description

  • Specifically detects Pro-Atrial Natriuretic Peptide Clone: 11E3.9 in Human, Rat samples, and it is validated for Immunohistochemistry (Paraffin), Western Blotting Natriuretic peptides A (UniProt P01160; also known as Atriopeptin, Cardiodilatin, Cardiodilatin-related peptide, Cardionatrin, CDD, CDD-ANF, CDP, Natriuretic peptide precursor A, Prepronatriodilatin) is encoded by the NPPA (also known as ANF, ANP, ATFB6, ATRST2, PND) gene (Gene ID 4878) in human
  • Atrial natriuretic peptide (ANP), also called atrial natriuretic factor, is a cardiac hormone that reduces high blood pressure by promoting salt excretion, decreasing blood volume, and relaxing vessel tension in a receptor-dependent manner
  • Deficiency in either ANP or its receptor causes spontaneous hypertension in knockout mice
  • ANP is initially synthesized in cardiac myocytes as a 153 a.a
  • precursor with a signal (a.a.1-25) and a propeptide (a.a
  • 26-123) sequence
  • The removal of the signal peptide yields pro-ANP (a.a
  • 26-151), which is further cleaved by the transmembrane cardiac serine protease Corin to yield mature ANP (a.a
  • 124-151), also known as atrial natriuretic factor (ANF)
  • ANP is a short-lived molecule partly due to its proteolytic degradation by the kidney Neprilysin, also known as neutral endopeptidase 24.11.

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MABC1032MI

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Antigen:
Pro-Atrial Natriuretic Peptide

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene Accession No.:
P01160

Host Species:
Mouse

Purification Method:
Protein G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
Expected to react with both prepro- and pro-atrial natriuretic peptide (ANP), but not mature ANP (a.a. 124-151 of prepro sequence).

Content And Storage:
2°C to 8°C for one year from date of shipment

Isotype:
IgG1 κ

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
11E3.9

Formulation:
Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.

Gene Symbols:
NPPA, ANP, PND

Immunogen:
His-tagged recombinant protein corresponding to human Pro-Atrial Natriuretic Peptide.

Quantity:
100 μg

Research Discipline:
Apoptosis, Cancer

Gene ID (Entrez):
NP_006163

Target Species:
Human, Rat

Form:
Purified

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Antigen:
Sp100

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene Accession No.:
P23497

Host Species:
Mouse

Purification Method:
Protein G Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
Clone 2H1.1 targeted epitope region is present in all seven human Sp100 spliced isoforms reported by UniProt (P23497).

Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.

Isotype:
IgG1 κ

Applications:
Western Blot

Clone:
2H1.1

Formulation:
Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.

Gene Symbols:
__

Immunogen:
GST-tagged recombinant human Sp100 internal fragment.

Quantity:
100 μg

Research Discipline:
Apoptosis & Cancer

Gene ID (Entrez):
NP_003104

Target Species:
Human

Form:
Purified

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Antigen:
NQO2

Classification:
Monoclonal

Conjugate:
__

Gene Accession No.:
P16083

Host Species:
Mouse

Purification Method:
Protein G Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
__

Content And Storage:
Stable for one year at 2°C to 8°C from date of receipt.

Isotype:
IgG2b κ

Applications:
Immunohistochemistry, Western Blot

Clone:
4A4.1

Formulation:
Purified mouse monoclonal IgG2bκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.

Gene Symbols:
NQO2; NMOR2

Immunogen:
GST-tagged recombinant human NQO2 N-terminal fragment.

Quantity:
100 μg

Research Discipline:
Apoptosis, Cancer

Gene ID (Entrez):
NP_000895

Target Species:
Human

Form:
Purified

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Antigen:
MTH1

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene Accession No.:
P36639

Host Species:
Mouse

Purification Method:
Protein G Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
Clone 11A3.2 recognizes an epitope present in all four spliced isoforms of human NUDT1/MTH1 reported by UniProt (P36639).

Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.

Isotype:
IgG1 κ

Applications:
Western Blot

Clone:
11A3.2

Formulation:
Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.

Gene Symbols:
__

Immunogen:
GST-tagged recombinant human MTH1 C-terminal fragment.

Quantity:
100 μg

Research Discipline:
Apoptosis & Cancer

Gene ID (Entrez):
NP_002443

Target Species:
Human

Form:
Purified