MABC289MI
MilliporeSigma™ Mouse anti-FYVE (Alfy domain), Clone: 5B11.1,
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | MABC289MI-Each-of-1 | In Stock | ₹ 41,563.00 |
MABC289MI - Each of 1
In Stock
Quantity
1
Base Price: ₹ 41,563.00
GST (18%): ₹ 7,481.34
Total Price: ₹ 49,044.34
Antigen
FYVE (Alfy domain)
Classification
Monoclonal
Formulation
Purified mouse monoclonal IgG2aκ in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols
WDFY3; KIAA0993
Immunogen
GST-tagged recombinant protein corresponding to human FYVE (Alfy domain).
Quantity
100 μg
Research Discipline
Apoptosis, Cancer
Gene ID (Entrez)
NP_055806
Content And Storage
Stable for one year at 2°C to 8°C from date of receipt.
Isotype
IgG2a κ
Applications
Immunocytochemistry, Immunoprecipitation, Western Blot
Clone
5B11.1
Gene Accession No.
Q8IZQ1
Host Species
Mouse
Purification Method
Protein G Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Target Species
Human
Form
Purified
Related Products
Description
- Specifically detects FYVE (Alfy domain) clone: 5B11.1 in Human samples, and it is validated for Immunocytochemistry, Immunoprecipitation, Western Blotting Phosphatidylinositol-3-phosphate [PtdIns(3)P] regulates endocytic and autophagic membrane traffic
- PtdIns(3)P-binding proteins, many of which contain FYVE zinc-finger domains play important roles in the metabolism of PtdIns(3)P
- The FYVE-protein Alfy, is a large, scaffolding, multi-domain, PtdIns(3)P binding protein that is implicated in autophagy trafficking
- Alfy is widely expressed and localizes to the nuclear membranes during normal cell health but relocalizes to autophagic membranes and ubiquitin containing aggregates during cellular stress
- Alfy is also a LC3 binding protein and binds GABARAPs too
- Binding of Alfy to GABARAP is indispensable for its recruitment to LC3B-positive structures and thus, for the clearance of certain p62 structures by autophagy
- Latest research indicates that Alfy is also important in regulating autophagy's role in various diseases including rheumatoid arthritis and neurological diseases.
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Antigen: FYVE (Alfy domain)
Classification: Monoclonal
Formulation: Purified mouse monoclonal IgG2aκ in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols: WDFY3; KIAA0993
Immunogen: GST-tagged recombinant protein corresponding to human FYVE (Alfy domain).
Quantity: 100 μg
Research Discipline: Apoptosis, Cancer
Gene ID (Entrez): NP_055806
Content And Storage: Stable for one year at 2°C to 8°C from date of receipt.
Isotype: IgG2a κ
Applications: Immunocytochemistry, Immunoprecipitation, Western Blot
Clone: 5B11.1
Gene Accession No.: Q8IZQ1
Host Species: Mouse
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human
Form: Purified
Antigen:
FYVE (Alfy domain)
Classification:
Monoclonal
Formulation:
Purified mouse monoclonal IgG2aκ in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols:
WDFY3; KIAA0993
Immunogen:
GST-tagged recombinant protein corresponding to human FYVE (Alfy domain).
Quantity:
100 μg
Research Discipline:
Apoptosis, Cancer
Gene ID (Entrez):
NP_055806
Content And Storage:
Stable for one year at 2°C to 8°C from date of receipt.
Isotype:
IgG2a κ
Applications:
Immunocytochemistry, Immunoprecipitation, Western Blot
Clone:
5B11.1
Gene Accession No.:
Q8IZQ1
Host Species:
Mouse
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Human
Form:
Purified
Antigen: TAOK1 (long isoform)
Classification: Monoclonal
Formulation: Purified mouse monoclonal IgG2bκ in buffer containing 0.1MTris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols: TAOK1, KIAA1361, MAP3K16, MARKK
Immunogen: Linear peptide corresponding to the C-terminus of human TAOK1.
Quantity: 100 μg
Research Discipline: __
Gene ID (Entrez): __
Content And Storage: 2-8°C for one year
Isotype: IgG2b κ
Applications: Western Blot
Clone: 1.2
Gene Accession No.: NP_065842
Host Species: Mouse
Purification Method: Protein G purified
Regulatory Status: __
Primary or Secondary: Primary
Target Species: Human
Form: Purified
Antigen:
TAOK1 (long isoform)
Classification:
Monoclonal
Formulation:
Purified mouse monoclonal IgG2bκ in buffer containing 0.1MTris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols:
TAOK1, KIAA1361, MAP3K16, MARKK
Immunogen:
Linear peptide corresponding to the C-terminus of human TAOK1.
Quantity:
100 μg
Research Discipline:
__
Gene ID (Entrez):
__
Content And Storage:
2-8°C for one year
Isotype:
IgG2b κ
Applications:
Western Blot
Clone:
1.2
Gene Accession No.:
NP_065842
Host Species:
Mouse
Purification Method:
Protein G purified
Regulatory Status:
__
Primary or Secondary:
Primary
Target Species:
Human
Form:
Purified
Antigen: NLRP10
Classification: Monoclonal
Formulation: Purified rat monoclonal IgG2aκ in buffer containing 0.1MTris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols: NLRP10, NAPL10, NOD8, PYNOD
Immunogen: Recombinant protein corresponding to human NLRP10.
Quantity: 100 μg
Research Discipline: __
Gene ID (Entrez): __
Content And Storage: 2-8°C for one year
Isotype: IgG2a κ
Applications: Flow Cytometry, Immunocytochemistry, Western Blot
Clone: 8H2
Gene Accession No.: NP_789791
Host Species: Rat
Purification Method: Protein G purified
Regulatory Status: __
Primary or Secondary: Primary
Target Species: Human
Form: Purified
Antigen:
NLRP10
Classification:
Monoclonal
Formulation:
Purified rat monoclonal IgG2aκ in buffer containing 0.1MTris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols:
NLRP10, NAPL10, NOD8, PYNOD
Immunogen:
Recombinant protein corresponding to human NLRP10.
Quantity:
100 μg
Research Discipline:
__
Gene ID (Entrez):
__
Content And Storage:
2-8°C for one year
Isotype:
IgG2a κ
Applications:
Flow Cytometry, Immunocytochemistry, Western Blot
Clone:
8H2
Gene Accession No.:
NP_789791
Host Species:
Rat
Purification Method:
Protein G purified
Regulatory Status:
__
Primary or Secondary:
Primary
Target Species:
Human
Form:
Purified
Antigen: phospho-ULK1 (Ser 467)
Classification: Monoclonal
Formulation: Purified mouse monoclonal IgMλ supernatant in buffer containing PBS with 0.05% sodium azide.
Gene Symbols: ULK1, KIAA0722
Immunogen: KLH-conjugated linear peptide corresponding to human phospho-ULK1 (Ser 467).
Quantity: 100 μg
Research Discipline: __
Gene ID (Entrez): __
Content And Storage: 2-8°C for one year
Isotype: IgGM λ
Applications: Western Blot
Clone: 15D12.3
Gene Accession No.: NP_003556
Host Species: Mouse
Purification Method: Protein G purified
Regulatory Status: __
Primary or Secondary: Primary
Target Species: Human
Form: Purified
Antigen:
phospho-ULK1 (Ser 467)
Classification:
Monoclonal
Formulation:
Purified mouse monoclonal IgMλ supernatant in buffer containing PBS with 0.05% sodium azide.
Gene Symbols:
ULK1, KIAA0722
Immunogen:
KLH-conjugated linear peptide corresponding to human phospho-ULK1 (Ser 467).
Quantity:
100 μg
Research Discipline:
__
Gene ID (Entrez):
__
Content And Storage:
2-8°C for one year
Isotype:
IgGM λ
Applications:
Western Blot
Clone:
15D12.3
Gene Accession No.:
NP_003556
Host Species:
Mouse
Purification Method:
Protein G purified
Regulatory Status:
__
Primary or Secondary:
Primary
Target Species:
Human
Form:
Purified