MABC269MI

MilliporeSigma™ Mouse anti-FANCC, Clone: 9A3.1,

Manufacturer: MilliporeSigma™

Select a Size

Pack Size SKU Availability Price
Each of 1 MABC269MI-Each-of-1 In Stock ₹ 42,677.33

MABC269MI - Each of 1

₹ 42,677.33

In Stock

Quantity

1

Base Price: ₹ 42,677.33

GST (18%): ₹ 7,681.919

Total Price: ₹ 50,359.249

Antigen

FANCC

Classification

Monoclonal

Formulation

Purified mouse monoclonal IgG1κ in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.

Gene Symbols

FANCC; FAC; FACC

Immunogen

GST-tagged recombinant protein corresponding to human FANCC.

Quantity

100 μg

Research Discipline

Apoptosis, Cancer

Gene ID (Entrez)

NP_000127

Content And Storage

Stable for one year at 2°C to 8°C from date of receipt.

Isotype

IgG1 κ

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin)

Clone

9A3.1

Gene Accession No.

Q00597

Host Species

Mouse

Purification Method

Protein G Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Target Species

Human

Form

Purified

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Description

  • Specifically detects FANCC clone: 9A3.1 in Human samples, and it is validated for Immunocytochemistry, Immunohistochemistry (Paraffin) Fanconi anemia (FA) is an inherited bone marrow failure syndrome associated with a progressive decline in hematopoietic stem cells, developmental defects, and predisposition to cancer
  • FANCC is part of the multisubunit Fanconi anemia (FA) complex composed of FANCA, FANCB, FANCC, FANCE, FANCF, FANCG, FANCL/PHF9 and FANCM
  • FANCC is a primarily nuclear localized DNA repair protein that is believed to function in interstrand DNA cross-link repair and the maintenance of normal chromosome stability
  • Mutations in FANCC are associated with various aspects of FA
  • New research shows that FANCC is critical for resistance to DNA cross-linking drug-induced DNA damage in cells of patients with myeloproliferative neoplasms
  • Also, FANCC interacts with the C-terminal-binding protein-1 (CtBP1) involved in transcriptional regulation, including being a negative regulator of Dickkopf-1 (DKK1) expression
  • This down regulation does not occur in mutations of FANCC, which then leads to up-regulation of DKK1, a molecule involved in hematopoietic malignancies.

Compare Similar Items

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MilliporeSigma™

MABC269MI

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Antigen:
FANCC

Classification:
Monoclonal

Formulation:
Purified mouse monoclonal IgG1κ in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.

Gene Symbols:
FANCC; FAC; FACC

Immunogen:
GST-tagged recombinant protein corresponding to human FANCC.

Quantity:
100 μg

Research Discipline:
Apoptosis, Cancer

Gene ID (Entrez):
NP_000127

Content And Storage:
Stable for one year at 2°C to 8°C from date of receipt.

Isotype:
IgG1 κ

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin)

Clone:
9A3.1

Gene Accession No.:
Q00597

Host Species:
Mouse

Purification Method:
Protein G Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human

Form:
Purified

Img

MilliporeSigma

MABC276MI

--


Antigen:
BAG3

Classification:
Monoclonal

Formulation:
Purified mouse monoclonal IgG1κ in buffer containing 0.1MTris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.

Gene Symbols:
BAG3, BIS

Immunogen:
MAP peptide corresponding to human BAG3.

Quantity:
100 μL

Research Discipline:
__

Gene ID (Entrez):
__

Content And Storage:
2-8°C for one year

Isotype:
IgG1 κ

Applications:
Western Blot

Clone:
AC-2

Gene Accession No.:
NP_004272

Host Species:
Mouse

Purification Method:
Protein G purified

Regulatory Status:
__

Primary or Secondary:
Primary

Target Species:
Human

Form:
Purified

Img

MilliporeSigma™

MABC277

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Antigen:
SOX9

Classification:
Monoclonal

Formulation:
Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.

Gene Symbols:
SOX9; CMD1; CMPD1; SRA1

Immunogen:
GST-tagged recombinant protein corresponding to a sequence from the N-terminal region of human SOX9.

Quantity:
100 μg

Research Discipline:
Apoptosis, Cancer

Gene ID (Entrez):
NP_000337

Content And Storage:
Stable for one year at 2°C to 8°C from date of receipt.

Isotype:
IgG1 κ

Applications:
Immunohistochemistry (Paraffin), Immunoprecipitation

Clone:
10E4.1

Gene Accession No.:
P48436

Host Species:
Mouse

Purification Method:
Protein G Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Form:
Purified

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MilliporeSigma

MABC282MI

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Antigen:
BAG3

Classification:
Monoclonal

Formulation:
Purified mouse monoclonal IgG1κ in buffer containing 0.1MTris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.

Gene Symbols:
BAG3, BIS

Immunogen:
MAP peptide corresponding to human BAG3.

Quantity:
100 μL

Research Discipline:
__

Gene ID (Entrez):
__

Content And Storage:
2-8°C for one year

Isotype:
IgG1 κ

Applications:
Immunohistochemistry, Immunoprecipitation

Clone:
AC-1

Gene Accession No.:
NP_004272

Host Species:
Mouse

Purification Method:
Protein G purified

Regulatory Status:
__

Primary or Secondary:
Primary

Target Species:
Human

Form:
Purified