MABS430MI

MilliporeSigma™ Mouse anti-Mcpip1, Clone: 2H8.2,

Manufacturer: MilliporeSigma™

Select a Size

Pack Size SKU Availability Price
Each of 1 MABS430MI-Each-of-1 In Stock ₹ 37,453.03

MABS430MI - Each of 1

₹ 37,453.03

In Stock

Quantity

1

Base Price: ₹ 37,453.03

GST (18%): ₹ 6,741.545

Total Price: ₹ 44,194.575

Antigen

Mcpip1

Classification

Monoclonal

Formulation

Purified mouse monoclonal IgG2aκ in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.

Gene Symbols

ZC3H12A; MCPIP; MCPIP1

Immunogen

GST-tagged recombinant protein corresponding to human Mcpip1.

Quantity

100 μg

Research Discipline

Signaling

Gene ID (Entrez)

NP_079355

Content And Storage

Stable for one year at 2°C to 8°C from date of receipt.

Isotype

IgG2a κ

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin)

Clone

2H8.2

Gene Accession No.

Q5D1E8

Host Species

Mouse

Purification Method

Protein G Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Target Species

Human

Form

Purified

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Description

  • Specifically detects Mcpip1 clone: 2H8.2 in Human samples, and it is validated for Immunocytochemistry, Immunohistochemistry (Paraffin) MCP-induced protein 1 (also known as ribonuclease ZC3H12A, Zinc finger CCCH domain-containing protein 12A) is encoded by the ZC3H12A gene in human (also known as dJ423B22.1, MCPIP, MCPIP1)
  • It belongs to the 4-member CCCH-zinc finger protein family (MCPIP1/2/3/4) that act as negative regulators in macrophage activation (PMID 18178554)
  • MCPIP1 in particular is involved in immune response downregulation upon LPS treatment by targeting IL-6 and IL-12b with its RNase activity (PMID 22561375)
  • MCPIP1 expresssion by MCP-1 treatment is reported to promote angiogenesis in human umbilical vein endothelial cell (HUVEC) cultures, while causing apoptotic cell death in cardiac myocytes (PMID 18364357 & 16574901).

Compare Similar Items

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Img

MilliporeSigma™

MABS430MI

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Antigen:
Mcpip1

Classification:
Monoclonal

Formulation:
Purified mouse monoclonal IgG2aκ in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.

Gene Symbols:
ZC3H12A; MCPIP; MCPIP1

Immunogen:
GST-tagged recombinant protein corresponding to human Mcpip1.

Quantity:
100 μg

Research Discipline:
Signaling

Gene ID (Entrez):
NP_079355

Content And Storage:
Stable for one year at 2°C to 8°C from date of receipt.

Isotype:
IgG2a κ

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin)

Clone:
2H8.2

Gene Accession No.:
Q5D1E8

Host Species:
Mouse

Purification Method:
Protein G Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human

Form:
Purified

Img

MilliporeSigma™

MABS432MI

--


Antigen:
MEK1

Classification:
Monoclonal

Formulation:
Purified mouse monoclonal IgG2aκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.

Gene Symbols:
MAP2K1, MEK1, PRKMK1

Immunogen:
GST-tagged recombinant protein corresponding to the C-terminal region of human MEK1.

Quantity:
100 μg

Research Discipline:
Signaling

Gene ID (Entrez):
NP_002746

Content And Storage:
2°C to 8°C for one year from date of shipment

Isotype:
IgG2a κ

Applications:
Western Blot

Clone:
6B7.1

Gene Accession No.:
Q02750

Host Species:
Mouse

Purification Method:
Protein G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human

Form:
Purified

Img

MilliporeSigma™

MABS434

--


Antigen:
PCSK9

Classification:
Monoclonal

Formulation:
Mouse IgG2a hybridoma culture supernatant without azide.

Gene Symbols:
__

Immunogen:
GST-tagged recombinant human mature NARC-1 (PCSK9) N-terminal fragment.

Quantity:
200 μL

Research Discipline:
Signaling

Gene ID (Entrez):
NP_777596

Content And Storage:
Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.

Isotype:
IgG2a κ

Applications:
Western Blot

Clone:
9B3.1

Gene Accession No.:
Q8NBP7

Host Species:
Mouse

Purification Method:
Unpurified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human

Form:
Culture Supernatant

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MilliporeSigma

MABS441MI

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Antigen:
WBP2

Classification:
Monoclonal

Formulation:
Purified mouse monoclonal IgG1κ in buffer containing 0.1MTris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.

Gene Symbols:
WBP2

Immunogen:
GST-tagged full length recombinant protein corresponding to Human WBP2.

Quantity:
100 μL

Research Discipline:
__

Gene ID (Entrez):
__

Content And Storage:
2-8°C for one year

Isotype:
IgG1 κ

Applications:
Immunocytochemistry, Immunoprecipitation, Western Blot

Clone:
4C8H10

Gene Accession No.:
NP_036610

Host Species:
Mouse

Purification Method:
Protein G purified

Regulatory Status:
__

Primary or Secondary:
Primary

Target Species:
Human

Form:
Purified