MABS1156MI
MilliporeSigma™ Mouse anti-Fibrocystin, Clone: 18,
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | MABS1156MI-Each-of-1 | In Stock | ₹ 38,734.72 |
MABS1156MI - Each of 1
In Stock
Quantity
1
Base Price: ₹ 38,734.72
GST (18%): ₹ 6,972.25
Total Price: ₹ 45,706.97
Antigen
Fibrocystin
Classification
Monoclonal
Formulation
Purified mouse monoclonal IgG2aκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols
PKHD1; FCYT; TIGM1
Immunogen
Recombinant protein corresponding to human Fibrocystin fragment from the N-terminal half.
Quantity
100 μg
Research Discipline
Signaling
Gene ID (Entrez)
NP_619639
Content And Storage
Stable for one year at 2°C to 8°C from date of receipt.
Isotype
IgG2a κ
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin)
Clone
18
Gene Accession No.
P08F94
Host Species
Mouse
Purification Method
Protein G Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Target Species
Human, Rat
Form
Purified
Related Products
Description
- Specifically detects Fibrocystin clone: 18 in Human, Rat samples, and it is validated for Immunocytochemistry, Immunohistochemistry (Paraffin) Fibrocystin (UniProt P08F94; also known as Polycystic kidney and hepatic disease 1 protein, Polyductin, Tigmin, TIG multiple domains 1, Tigmin) is encoded by the PKHD1 (also known as ARPKD, FCYT, TIGM1) gene (Gene ID 5314) in human
- Autosomal recessive polycystic kidney disease (ARPKD) is the most common cause of hereditary childhood PKD
- ARPKD is caused by mutations in the gene PKHD1, which encodes fibrocystin/polyductin (FCP), while mutations in two other genes PKD1 and PKD2 that code polycystin-1 (PC1) and polycystin-2 (PC2), respectively, are the cause of autosomal dominant PKD (ADPKD)
- These three PKD proteins have been localized to renal primary cilia, where the PC1/PC2 complex acts as a flow sensor on the cilium
- Fibrocystin is known to complex with PC2, but its biological role is unclear, While Uniprot (P08F94) documents two alternatively spliced human fibrocytin isoforms, multiple lines of evidence indicate that many more spliced mRNA transcripts exist and that aberrant mRNA splicing may represent a pathogenic mechanism in ARPKD in addition to gene mutations.
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Antigen: Fibrocystin
Classification: Monoclonal
Formulation: Purified mouse monoclonal IgG2aκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols: PKHD1; FCYT; TIGM1
Immunogen: Recombinant protein corresponding to human Fibrocystin fragment from the N-terminal half.
Quantity: 100 μg
Research Discipline: Signaling
Gene ID (Entrez): NP_619639
Content And Storage: Stable for one year at 2°C to 8°C from date of receipt.
Isotype: IgG2a κ
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin)
Clone: 18
Gene Accession No.: P08F94
Host Species: Mouse
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human, Rat
Form: Purified
Antigen:
Fibrocystin
Classification:
Monoclonal
Formulation:
Purified mouse monoclonal IgG2aκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols:
PKHD1; FCYT; TIGM1
Immunogen:
Recombinant protein corresponding to human Fibrocystin fragment from the N-terminal half.
Quantity:
100 μg
Research Discipline:
Signaling
Gene ID (Entrez):
NP_619639
Content And Storage:
Stable for one year at 2°C to 8°C from date of receipt.
Isotype:
IgG2a κ
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin)
Clone:
18
Gene Accession No.:
P08F94
Host Species:
Mouse
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Human, Rat
Form:
Purified
Antigen: PYCR1
Classification: Monoclonal
Formulation: Purified mouse monoclonal IgG2bκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Symbols: __
Immunogen: GST-tagged recombinant protein corresponding to the C-terminal of human PYCR1.
Quantity: 100 μg
Research Discipline: Signaling
Gene ID (Entrez): NP_001269209
Content And Storage: Stable for 1 year at 2°-8°C from date of receipt.
Isotype: IgG2b κ
Applications: Western Blot
Clone: 2D9.1
Gene Accession No.: P32322
Host Species: Mouse
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human
Form: Purified
Antigen:
PYCR1
Classification:
Monoclonal
Formulation:
Purified mouse monoclonal IgG2bκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Symbols:
__
Immunogen:
GST-tagged recombinant protein corresponding to the C-terminal of human PYCR1.
Quantity:
100 μg
Research Discipline:
Signaling
Gene ID (Entrez):
NP_001269209
Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.
Isotype:
IgG2b κ
Applications:
Western Blot
Clone:
2D9.1
Gene Accession No.:
P32322
Host Species:
Mouse
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Human
Form:
Purified
Antigen: AdipoR2
Classification: Monoclonal
Formulation: Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Symbols: __
Immunogen: GST-tagged recombinant human AdipoR2 N-terminal fragment.
Quantity: 100 μL
Research Discipline: Signaling
Gene ID (Entrez): NP_078827
Content And Storage: Stable for 1 year at 2°-8°C from date of receipt.
Isotype: IgG1 κ
Applications: Western Blot
Clone: 4D3.2
Gene Accession No.: Q86V24
Host Species: Mouse
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human
Form: Purified
Antigen:
AdipoR2
Classification:
Monoclonal
Formulation:
Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Symbols:
__
Immunogen:
GST-tagged recombinant human AdipoR2 N-terminal fragment.
Quantity:
100 μL
Research Discipline:
Signaling
Gene ID (Entrez):
NP_078827
Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.
Isotype:
IgG1 κ
Applications:
Western Blot
Clone:
4D3.2
Gene Accession No.:
Q86V24
Host Species:
Mouse
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Human
Form:
Purified
Antigen: RagA/B
Classification: Monoclonal
Formulation: Purified mouse IgG2a in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Symbols: __
Immunogen: KLH-conjugated linear peptide corresponding to the C-terminal end sequence of human/mouse/rat RagA.
Quantity: 100 μL
Research Discipline: Signaling
Gene ID (Entrez): NP_006561
Content And Storage: Stable for 1 year at 2°-8°C from date of receipt.
Isotype: IgG2a κ
Applications: Immunocytochemistry, Western Blot
Clone: 1H7.1
Gene Accession No.: Q7L523
Host Species: Mouse
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human
Form: Purified
Antigen:
RagA/B
Classification:
Monoclonal
Formulation:
Purified mouse IgG2a in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Symbols:
__
Immunogen:
KLH-conjugated linear peptide corresponding to the C-terminal end sequence of human/mouse/rat RagA.
Quantity:
100 μL
Research Discipline:
Signaling
Gene ID (Entrez):
NP_006561
Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.
Isotype:
IgG2a κ
Applications:
Immunocytochemistry, Western Blot
Clone:
1H7.1
Gene Accession No.:
Q7L523
Host Species:
Mouse
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Human
Form:
Purified