MABS186MI

MilliporeSigma™ Mouse anti-LOX-1, Clone: 9E12.1,

Manufacturer: MilliporeSigma™

Select a Size

Pack Size SKU Availability Price
Each of 1 MABS186MI-Each-of-1 In Stock ₹ 31,588.75

MABS186MI - Each of 1

₹ 31,588.75

In Stock

Quantity

1

Base Price: ₹ 31,588.75

GST (18%): ₹ 5,685.975

Total Price: ₹ 37,274.725

Antigen

LOX-1

Classification

Monoclonal

Formulation

Purified mouse monoclonal IgG2aκ in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.

Gene Symbols

OLR1; CLEC8A; LOX1

Immunogen

GST-tagged recombinant protein corresponding to human LOX-1.

Quantity

100 μg

Research Discipline

Signaling

Gene ID (Entrez)

NP_001166103

Content And Storage

Stable for one year at 2°C to 8°C from date of receipt.

Isotype

IgG2a κ

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin)

Clone

9E12.1

Gene Accession No.

P78380

Host Species

Mouse

Purification Method

Protein G Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Target Species

Human

Form

Purified

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Description

  • Specifically detects LOX-1 clone: 9E12.1 in Human samples, and it is validated for Immunocytochemistry, Immunohistochemistry (Paraffin) LOX1 is a plasma membrane receptor, that also has a free soluble receptor form, that is the receptor that mediates the recognition, internalization and degradation of oxidatively modified low density lipoprotein (oxLDL) by vascular endothelial cells
  • OxLDL is a marker of atherosclerosis that induces vascular endothelial cell activation and dysfunction, resulting in pro-inflammatory responses, pro-oxidative conditions and apoptosis
  • Its association with oxLDL induces the activation of NF-kappa-B through an increased production of intracellular reactive oxygen and a variety of pro-atherogenic cellular responses including a reduction of nitric oxide (NO) release, monocyte adhesion and apoptosis
  • LOX1 is also the receptor for HSP70, and LOX1 acts as a leukocyte adhesion molecule on glycosylated proteins present on platelets, monocytes, bacteria, apoptotic cells in inflammatory responses.

Compare Similar Items

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MilliporeSigma™

MABS186MI

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Antigen:
LOX-1

Classification:
Monoclonal

Formulation:
Purified mouse monoclonal IgG2aκ in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.

Gene Symbols:
OLR1; CLEC8A; LOX1

Immunogen:
GST-tagged recombinant protein corresponding to human LOX-1.

Quantity:
100 μg

Research Discipline:
Signaling

Gene ID (Entrez):
NP_001166103

Content And Storage:
Stable for one year at 2°C to 8°C from date of receipt.

Isotype:
IgG2a κ

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin)

Clone:
9E12.1

Gene Accession No.:
P78380

Host Species:
Mouse

Purification Method:
Protein G Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human

Form:
Purified

Img

Fischer Scientific

MABS1889-100

--


Antigen:
FANCD2

Classification:
Monoclonal

Formulation:
Purified mouse monoclonal antibody IgG1 in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Gene Symbols:
FANCD2;FACD

Immunogen:
GST/His-tagged recombinant fragment corresponding to first 150 amino acids of human Fanconi anemia group D2 protein.

Quantity:
100 μg

Research Discipline:
Signaling

Gene ID (Entrez):
NP_149075

Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.

Isotype:
IgG1 κ

Applications:
Western Blot, Immunohistochemistry (Paraffin)

Clone:
10F8.1

Gene Accession No.:
__

Host Species:
Mouse

Purification Method:
Protein G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human

Form:
Purified

Img

Fischer Scientific

MABS1889-25

--


Antigen:
FANCD2

Classification:
Monoclonal

Formulation:
Purified mouse monoclonal antibody IgG1 in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Gene Symbols:
FANCD2;FACD

Immunogen:
GST/His-tagged recombinant fragment corresponding to first 150 amino acids of human Fanconi anemia group D2 protein.

Quantity:
25 μg

Research Discipline:
Signaling

Gene ID (Entrez):
NP_149075

Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.

Isotype:
IgG1 κ

Applications:
Western Blot, Immunohistochemistry (Paraffin)

Clone:
10F8.1

Gene Accession No.:
__

Host Species:
Mouse

Purification Method:
Protein G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human

Form:
Purified

Img

MilliporeSigma

MABS1896-25

--


Antigen:
RNF123

Classification:
Monoclonal

Formulation:
Purified mouse monoclonal antibody IgG1 in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Gene Symbols:
RNF123;KPC1;PF1477

Immunogen:
GST/His-tagged recombinant fragment corresponding to 92 amino acids from the N-terminal region of human RING-type E3 ubiquitin transferase RNF123.

Quantity:
25 μL

Research Discipline:
Signaling

Gene ID (Entrez):
NP_071347

Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.

Isotype:
IgG1 κ

Applications:
Western Blot

Clone:
2C10.1

Gene Accession No.:
__

Host Species:
Mouse

Purification Method:
Protein G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human

Form:
Purified