MABT388MI
MilliporeSigma™ Mouse anti-ADAM 17, Clone: 16C11.1,
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | MABT388MI-Each-of-1 | In Stock | ₹ 38,734.72 |
MABT388MI - Each of 1
In Stock
Quantity
1
Base Price: ₹ 38,734.72
GST (18%): ₹ 6,972.25
Total Price: ₹ 45,706.97
Antigen
ADAM 17
Classification
Monoclonal
Formulation
Purified mouse monoclonal IgG1κ in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols
ADAM17; CSVP; TACE
Immunogen
GST-tagged recombinant protein corresponding to human ADAM 17.
Quantity
100 μg
Research Discipline
Cell Structure
Gene ID (Entrez)
NP_003174
Content And Storage
Stable for one year at 2°C to 8°C from date of receipt.
Isotype
IgG1 κ
Applications
Immunohistochemistry (Paraffin), Western Blot
Clone
16C11.1
Gene Accession No.
P78536
Host Species
Mouse
Purification Method
Protein G Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Target Species
Human
Form
Purified
Related Products
Description
- Specifically detects ADAM 17 clone: 16C11.1 in Human samples, and it is validated for Immunohistochemistry (Paraffin), Western Blotting Disintegrin and metalloproteinase domain-containing protein 17 (EC 3.4.24.86; UniProt P78536; also known as ADAM 17, CD156b, Snake venom-like protease
- TNF-alpha convertase, TNF-alpha-converting enzyme, Tumor necrosis factor alpha-converting enzyme) is encoded by the ADAM17 (also known as CD156B, CSVP, NISBD, NISBD1, TACE) gene (Gene ID 6868) in human
- Originally described as a TNF–alpha converting enzyme, ADAM17 is known to process the cleavage of many transmembrane proteins, including membrane-anchored cytokines, cell adhesion molecules, receptors, ligands, and enzymes
- ADAM17 was the first 'sheddase' identified
- ADAM17 activity is regulated by multiple post-translational modifications
- It has three phosphorylation sites on its C-terminal cytoplasmic domain (T735, S791, and (S819)
- ERK1/2-mediated T735 phosphorylation is reported to regulate ADAM17 maturation and surface expression
- ADAM 17 is initially translated in its prepro-form and subsequent cleavages of the signal (aa 1-17) and propeptide (18-214) sequences produces the 610 aa mature ADAM 17 (aa 215-824).
Compare Similar Items
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Antigen: ADAM 17
Classification: Monoclonal
Formulation: Purified mouse monoclonal IgG1κ in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols: ADAM17; CSVP; TACE
Immunogen: GST-tagged recombinant protein corresponding to human ADAM 17.
Quantity: 100 μg
Research Discipline: Cell Structure
Gene ID (Entrez): NP_003174
Content And Storage: Stable for one year at 2°C to 8°C from date of receipt.
Isotype: IgG1 κ
Applications: Immunohistochemistry (Paraffin), Western Blot
Clone: 16C11.1
Gene Accession No.: P78536
Host Species: Mouse
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human
Form: Purified
Antigen:
ADAM 17
Classification:
Monoclonal
Formulation:
Purified mouse monoclonal IgG1κ in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols:
ADAM17; CSVP; TACE
Immunogen:
GST-tagged recombinant protein corresponding to human ADAM 17.
Quantity:
100 μg
Research Discipline:
Cell Structure
Gene ID (Entrez):
NP_003174
Content And Storage:
Stable for one year at 2°C to 8°C from date of receipt.
Isotype:
IgG1 κ
Applications:
Immunohistochemistry (Paraffin), Western Blot
Clone:
16C11.1
Gene Accession No.:
P78536
Host Species:
Mouse
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Human
Form:
Purified
Antigen: Laminin subunit alpha-4
Classification: Monoclonal
Formulation: Purified mouse monoclonal IgG1κ in buffer containing 0.1MTris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols: LAMA3, LAMA4
Immunogen: Recombinant protein corresponding to human Laminin subunit alpha-4.
Quantity: 100 μL
Research Discipline: __
Gene ID (Entrez): __
Content And Storage: 2-8°C for one year
Isotype: IgG1 κ
Applications: ELISA, Immunohistochemistry, Immunoprecipitation, Western Blot
Clone: 3H2
Gene Accession No.: NP_001098676
Host Species: Mouse
Purification Method: Protein G Purified
Regulatory Status: __
Primary or Secondary: Primary
Target Species: Human
Form: Purified
Antigen:
Laminin subunit alpha-4
Classification:
Monoclonal
Formulation:
Purified mouse monoclonal IgG1κ in buffer containing 0.1MTris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols:
LAMA3, LAMA4
Immunogen:
Recombinant protein corresponding to human Laminin subunit alpha-4.
Quantity:
100 μL
Research Discipline:
__
Gene ID (Entrez):
__
Content And Storage:
2-8°C for one year
Isotype:
IgG1 κ
Applications:
ELISA, Immunohistochemistry, Immunoprecipitation, Western Blot
Clone:
3H2
Gene Accession No.:
NP_001098676
Host Species:
Mouse
Purification Method:
Protein G Purified
Regulatory Status:
__
Primary or Secondary:
Primary
Target Species:
Human
Form:
Purified
Antigen: Syntaxin-2
Classification: Monoclonal
Formulation: Purified mouse monoclonal IgG2aκ in buffer containing 0.1MTris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols: STX2, EPIM, STX2A, STX2B, STX2C
Immunogen: GST-tagged recombinant protein corresponding to human Syntaxin-2.
Quantity: 100 μg
Research Discipline: __
Gene ID (Entrez): __
Content And Storage: 2-8°C for one year
Isotype: IgG2a κ
Applications: Immunocytochemistry, Western Blot
Clone: 2F2.1
Gene Accession No.: NP_001971
Host Species: Mouse
Purification Method: Protein G purified
Regulatory Status: __
Primary or Secondary: Primary
Target Species: Human
Form: Purified
Antigen:
Syntaxin-2
Classification:
Monoclonal
Formulation:
Purified mouse monoclonal IgG2aκ in buffer containing 0.1MTris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols:
STX2, EPIM, STX2A, STX2B, STX2C
Immunogen:
GST-tagged recombinant protein corresponding to human Syntaxin-2.
Quantity:
100 μg
Research Discipline:
__
Gene ID (Entrez):
__
Content And Storage:
2-8°C for one year
Isotype:
IgG2a κ
Applications:
Immunocytochemistry, Western Blot
Clone:
2F2.1
Gene Accession No.:
NP_001971
Host Species:
Mouse
Purification Method:
Protein G purified
Regulatory Status:
__
Primary or Secondary:
Primary
Target Species:
Human
Form:
Purified
Antigen: Myosin-10
Classification: Monoclonal
Formulation: Purified mouse monoclonal IgG1κ in buffer containing 0.1MTris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols: MYH10
Immunogen: GST-tagged recombinant protein corresponding to human Myosin-10.
Quantity: 100 μg
Research Discipline: __
Gene ID (Entrez): __
Content And Storage: 2-8°C for one year
Isotype: IgG1 κ
Applications: Western Blot
Clone: 5H4.1
Gene Accession No.: NP_001242941
Host Species: Mouse
Purification Method: Protein G purified
Regulatory Status: __
Primary or Secondary: Primary
Target Species: Human, Mouse
Form: Purified
Antigen:
Myosin-10
Classification:
Monoclonal
Formulation:
Purified mouse monoclonal IgG1κ in buffer containing 0.1MTris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols:
MYH10
Immunogen:
GST-tagged recombinant protein corresponding to human Myosin-10.
Quantity:
100 μg
Research Discipline:
__
Gene ID (Entrez):
__
Content And Storage:
2-8°C for one year
Isotype:
IgG1 κ
Applications:
Western Blot
Clone:
5H4.1
Gene Accession No.:
NP_001242941
Host Species:
Mouse
Purification Method:
Protein G purified
Regulatory Status:
__
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Form:
Purified