MABN898MI

MilliporeSigma™ FFAR3/GPR41, Mouse, Unlabeled, Clone: 16F4.1,

Manufacturer: MilliporeSigma™

Select a Size

Pack Size SKU Availability Price
Each of 1 MABN898MI-Each-of-1 In Stock ₹ 38,734.72

MABN898MI - Each of 1

₹ 38,734.72

In Stock

Quantity

1

Base Price: ₹ 38,734.72

GST (18%): ₹ 6,972.25

Total Price: ₹ 45,706.97

Antigen

FFAR3/GPR41

Classification

Monoclonal

Concentration

Please refer to lot specific datasheet.

Formulation

Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.

Gene Accession No.

O14843

Immunogen

KLH-conjugated linear peptide corresponding to a C-terminal cytoplasmic domain sequence of human FFAR3/GPR41.

Quantity

100 μg

Research Discipline

Neuroscience

Gene ID (Entrez)

NP_005295

Target Species

Human

Form

Purified

Applications

Western Blot

Clone

16F4.1

Conjugate

Unconjugated

Gene

FFAR3, GPR41

Host Species

Mouse

Purification Method

Protein G Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Test Specificity

Clone 16F4.1 targets an epitope in the C-terminal cytoplasmic domain of human FFAR3/GPR41.

Content And Storage

Stable for 1 year at 2°-8°C from date of receipt.

Isotype

IgG1 κ

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Description

  • Free fatty acid receptor 3 (UniProt O14843; also known as G-protein coupled receptor 41) is encoded by the FFAR3 (also known as GPR41) gene (Gene ID 2865) in human
  • Free fatty acids (FFAs) act as both energy sources and signaling molecules via G-protein-coupled receptors (GPCRs) called FFARs (FFA receptors)
  • FFAs are categorized by the length of their carbon chains into short-chain FAs (SCFAs; less than 6 carbons), medium-chain FAs (MCFAs; 6–12 carbons), and long-chain FAs (LCFAs; more than 12 carbons)
  • MCFAs and LCFAs activate FFAR1 and FFAR4, whereas SCFAs activate FFAR3 and FFAR2
  • FFAR3 is an SCFA receptor that can be activated by propionate (C3), butyrate (C4), and valerate (C5)
  • FFAR3 mediates PYY and GLP-1 secretion from endocrine and sympathetic outflow-dependent heart rate regulation and energy expenditure, while β-Hydroxybutyrate, a ketone body produced in the liver during starvation, decreases sympathetic outflow by antagonizing FFAR3
  • FFAR3 is shown to couple Gαi/o pathway signaling upon activation by propionate binding in primary murine pancreatic beta cells, resulting in an inhibition of glucose-dependent insulin secretion
  • FFAR3 is a 7-transmembrane (a.a
  • 20-40, 48-68, 89-111, 133-153, 179-199, 223-243, 259-279) GPCR, having a short N-terminal extracellular portion (a.a
  • 1-19) and a long C-terminal cytomplasmic tail (a.a
  • 280-346).

Compare Similar Items

Show Difference

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MilliporeSigma™

MABN898MI

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Antigen:
FFAR3/GPR41

Classification:
Monoclonal

Concentration:
Please refer to lot specific datasheet.

Formulation:
Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.

Gene Accession No.:
O14843

Immunogen:
KLH-conjugated linear peptide corresponding to a C-terminal cytoplasmic domain sequence of human FFAR3/GPR41.

Quantity:
100 μg

Research Discipline:
Neuroscience

Gene ID (Entrez):
NP_005295

Target Species:
Human

Form:
Purified

Applications:
Western Blot

Clone:
16F4.1

Conjugate:
Unconjugated

Gene:
FFAR3, GPR41

Host Species:
Mouse

Purification Method:
Protein G Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
Clone 16F4.1 targets an epitope in the C-terminal cytoplasmic domain of human FFAR3/GPR41.

Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.

Isotype:
IgG1 κ

Img

MilliporeSigma™

MABN92AF555

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Antigen:
Iba1/AIF1

Classification:
Monoclonal

Concentration:
__

Formulation:
Purified mouse antibody conjugate in PBS with 15mg/mL BSA and 0.1 % sodium azide.

Gene Accession No.:
P55008

Immunogen:
Linear peptide corresponding to a human Iba1/AIF1 sequence.

Quantity:
100 μL

Research Discipline:
Neuroscience

Gene ID (Entrez):
NP_001614

Target Species:
Human, Mouse, Rat

Form:
Purified

Applications:
Immunohistochemistry

Clone:
20A12.1

Conjugate:
Alexa Fluor 555

Gene:
__

Host Species:
Mouse

Purification Method:
Protein G purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
__

Content And Storage:
2°C to 8°C for one year from date of shipment

Isotype:
IgG1 κ

Img

MilliporeSigma

MABN92MI

--


Antigen:
Iba1/AIF1

Classification:
Monoclonal

Concentration:
__

Formulation:
Purified mouse monoclonal IgG1κ in buffer containing 0.1MTris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.

Gene Accession No.:
NP_001614

Immunogen:
Linear peptide corresponding to human Iba1/AIF1.

Quantity:
100 μg

Research Discipline:
__

Gene ID (Entrez):
__

Target Species:
Human, Mouse, Rat

Form:
Purified

Applications:
Immunohistochemistry, Western Blot

Clone:
20A12.1

Conjugate:
Unconjugated

Gene:
__

Host Species:
Mouse

Purification Method:
Protein G purified

Regulatory Status:
__

Primary or Secondary:
Primary

Test Specificity:
__

Content And Storage:
2-8°C for one year

Isotype:
IgG1 κ

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MilliporeSigma™

MABS1131MI

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Antigen:
SFRP3

Classification:
Monoclonal

Concentration:
Please refer to lot specific datasheet.

Formulation:
Purified mouse monoclonal IgG2bκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.

Gene Accession No.:
Q92765

Immunogen:
GST-tagged recombinant human SFRP3 Netrin (NTR) domain fragment.

Quantity:
100 μg

Research Discipline:
Signaling

Gene ID (Entrez):
NP_001454

Target Species:
Human

Form:
Purified

Applications:
Western Blot

Clone:
14G11.2

Conjugate:
Unconjugated

Gene:
FRZB, FIZ, FRE, FRP, FRZB1, SFRP3

Host Species:
Mouse

Purification Method:
Protein G Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
Clone 14G11.2 recognizes an epitope within the netrin (NTR) domain of human secreted frizzled-related protein 3 (sFRP-3).

Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.

Isotype:
IgG2b κ