MABS1131MI
MilliporeSigma™ SFRP3, Mouse, Unlabeled, Clone: 14G11.2,
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | MABS1131MI-Each-of-1 | In Stock | ₹ 38,734.72 |
MABS1131MI - Each of 1
In Stock
Quantity
1
Base Price: ₹ 38,734.72
GST (18%): ₹ 6,972.25
Total Price: ₹ 45,706.97
Antigen
SFRP3
Classification
Monoclonal
Concentration
Please refer to lot specific datasheet.
Formulation
Purified mouse monoclonal IgG2bκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.
Q92765
Immunogen
GST-tagged recombinant human SFRP3 Netrin (NTR) domain fragment.
Quantity
100 μg
Research Discipline
Signaling
Gene ID (Entrez)
NP_001454
Target Species
Human
Form
Purified
Applications
Western Blot
Clone
14G11.2
Conjugate
Unconjugated
Gene
FRZB, FIZ, FRE, FRP, FRZB1, SFRP3
Host Species
Mouse
Purification Method
Protein G Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Test Specificity
Clone 14G11.2 recognizes an epitope within the netrin (NTR) domain of human secreted frizzled-related protein 3 (sFRP-3).
Content And Storage
Stable for 1 year at 2°-8°C from date of receipt.
Isotype
IgG2b κ
Related Products
Description
- Secreted frizzled-related protein 3 (UniProt Q92765; also known as Frezzled, Fritz, FrzB-1, Frizzled-related protein 1, sFRP-3) is encoded by the FRZB (also known as FIZ, FRE, FRP, FRZB1, SFRP3) gene (Gene ID 2487) in human
- Canonical Wnt signaling is constitutively suppressed in the absence of Wnt, and its activation in the presence of Wnt can be blocked by secreted inhibitors, including the dickkopf-related proteins (DKK) and the secreted frizzled-related proteins (sFRP1-5)
- sFRPs share homology with the FZD receptor and compete againt FZD for Wnt binding in the extracellular space, sFRPs may also exert their effects by interacting with each other and FZD receptors
- sFRP-3 plays a role in regulating cell growth and differentiation in specific cell types, such as adult hippocampal neural stem cell activation and chondrocyte maturation
- sFRP-3 is produced with a signal peptide sequence (a.a
- 1-32), the removal of which yields the mature protein with an N-terminal FZ (a.a
- 33-150) domain, followed by a netrin (NTR) domain (a.a
- 178-298) and a C-terminal Ser-rich region.
Compare Similar Items
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Antigen: SFRP3
Classification: Monoclonal
Concentration: Please refer to lot specific datasheet.
Formulation: Purified mouse monoclonal IgG2bκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.: Q92765
Immunogen: GST-tagged recombinant human SFRP3 Netrin (NTR) domain fragment.
Quantity: 100 μg
Research Discipline: Signaling
Gene ID (Entrez): NP_001454
Target Species: Human
Form: Purified
Applications: Western Blot
Clone: 14G11.2
Conjugate: Unconjugated
Gene: FRZB, FIZ, FRE, FRP, FRZB1, SFRP3
Host Species: Mouse
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Clone 14G11.2 recognizes an epitope within the netrin (NTR) domain of human secreted frizzled-related protein 3 (sFRP-3).
Content And Storage: Stable for 1 year at 2°-8°C from date of receipt.
Isotype: IgG2b κ
Antigen:
SFRP3
Classification:
Monoclonal
Concentration:
Please refer to lot specific datasheet.
Formulation:
Purified mouse monoclonal IgG2bκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.:
Q92765
Immunogen:
GST-tagged recombinant human SFRP3 Netrin (NTR) domain fragment.
Quantity:
100 μg
Research Discipline:
Signaling
Gene ID (Entrez):
NP_001454
Target Species:
Human
Form:
Purified
Applications:
Western Blot
Clone:
14G11.2
Conjugate:
Unconjugated
Gene:
FRZB, FIZ, FRE, FRP, FRZB1, SFRP3
Host Species:
Mouse
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Clone 14G11.2 recognizes an epitope within the netrin (NTR) domain of human secreted frizzled-related protein 3 (sFRP-3).
Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.
Isotype:
IgG2b κ
Antigen: SUMO2/3
Classification: Monoclonal
Concentration: Please refer to lot specific datasheet.
Formulation: Rat IgG2a hybridoma culture supernatant with 0.05% Sodium Azide.
Gene Accession No.: P61956;P55854
Immunogen: GST-tagged recombinant full-length human SUMO3 (Uchimura, Y., et al. (2006). J. Biol. Chem. 281(32):23180-23190).
Quantity: 100 μL
Research Discipline: Signaling
Gene ID (Entrez): NP_008868;NP_008867
Target Species: Human
Form: __
Applications: Western Blot
Clone: 3H12
Conjugate: Unconjugated
Gene: SUMO2, SMT3B, SMT3H2, SUMO3, SMT3A, SMT3H1
Host Species: Rat
Purification Method: Unpurified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Clone 3H12 detects SUMO2/3 and SUMO2/3-modified (SUMOylated) proteins. Clone 3H12 reacts with SUMO2/3, but not SUMO1 (Uchimura, Y., et al. (2006). J. Biol. Chem. 281(32):23180-23190).
Content And Storage: Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Isotype: IgG2a κ
Antigen:
SUMO2/3
Classification:
Monoclonal
Concentration:
Please refer to lot specific datasheet.
Formulation:
Rat IgG2a hybridoma culture supernatant with 0.05% Sodium Azide.
Gene Accession No.:
P61956;P55854
Immunogen:
GST-tagged recombinant full-length human SUMO3 (Uchimura, Y., et al. (2006). J. Biol. Chem. 281(32):23180-23190).
Quantity:
100 μL
Research Discipline:
Signaling
Gene ID (Entrez):
NP_008868;NP_008867
Target Species:
Human
Form:
__
Applications:
Western Blot
Clone:
3H12
Conjugate:
Unconjugated
Gene:
SUMO2, SMT3B, SMT3H2, SUMO3, SMT3A, SMT3H1
Host Species:
Rat
Purification Method:
Unpurified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Clone 3H12 detects SUMO2/3 and SUMO2/3-modified (SUMOylated) proteins. Clone 3H12 reacts with SUMO2/3, but not SUMO1 (Uchimura, Y., et al. (2006). J. Biol. Chem. 281(32):23180-23190).
Content And Storage:
Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Isotype:
IgG2a κ
Antigen: Fgr
Classification: Monoclonal
Concentration: __
Formulation: Purified mouse monoclonal IgG2aκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Accession No.: P09769
Immunogen: Recombinant protein corresponding to human Fgr.
Quantity: 100 μg
Research Discipline: Signaling
Gene ID (Entrez): NP_001036194
Target Species: Human
Form: Purified
Applications: Western Blot
Clone: SuGr-7 14F3
Conjugate: __
Gene: __
Host Species: Mouse
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: __
Content And Storage: Stable for one year at 2°C to 8°C from date of receipt.
Isotype: IgG2a κ
Antigen:
Fgr
Classification:
Monoclonal
Concentration:
__
Formulation:
Purified mouse monoclonal IgG2aκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Accession No.:
P09769
Immunogen:
Recombinant protein corresponding to human Fgr.
Quantity:
100 μg
Research Discipline:
Signaling
Gene ID (Entrez):
NP_001036194
Target Species:
Human
Form:
Purified
Applications:
Western Blot
Clone:
SuGr-7 14F3
Conjugate:
__
Gene:
__
Host Species:
Mouse
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
__
Content And Storage:
Stable for one year at 2°C to 8°C from date of receipt.
Isotype:
IgG2a κ
Antigen: SH2D1A
Classification: Monoclonal
Concentration: Please refer to lot specific datasheet.
Formulation: Purified mouse monoclonal IgG2bκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.: O60880
Immunogen: Recombinant full-length human SH2D1A.
Quantity: 100 μg
Research Discipline: Signaling
Gene ID (Entrez): NP_002342
Target Species: Human
Form: Purified
Applications: Western Blot
Clone: SuGr-20 18A9
Conjugate: Unconjugated
Gene: SH2D1A, DSHP, SAP, XLP, XLP1, XLPD
Host Species: Mouse
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Clone SuGr-20 18A9 recognizes recombinant full-length human SH2D1A spliced isoform A (UniProt O60880-1) by Western blotting. Reactivity toward spliced isoforms B to F (UniProt O60880-2 to O60880-6) has not been determined.
Content And Storage: Stable for 1 year at 2°-8°C from date of receipt.
Isotype: IgG2b κ
Antigen:
SH2D1A
Classification:
Monoclonal
Concentration:
Please refer to lot specific datasheet.
Formulation:
Purified mouse monoclonal IgG2bκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.:
O60880
Immunogen:
Recombinant full-length human SH2D1A.
Quantity:
100 μg
Research Discipline:
Signaling
Gene ID (Entrez):
NP_002342
Target Species:
Human
Form:
Purified
Applications:
Western Blot
Clone:
SuGr-20 18A9
Conjugate:
Unconjugated
Gene:
SH2D1A, DSHP, SAP, XLP, XLP1, XLPD
Host Species:
Mouse
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Clone SuGr-20 18A9 recognizes recombinant full-length human SH2D1A spliced isoform A (UniProt O60880-1) by Western blotting. Reactivity toward spliced isoforms B to F (UniProt O60880-2 to O60880-6) has not been determined.
Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.
Isotype:
IgG2b κ