MABS826MI

MilliporeSigma™ Rsk1, Mouse, Unlabeled, Clone: 3G5.1,

Manufacturer: MilliporeSigma™

Select a Size

Pack Size SKU Availability Price
Each of 1 MABS826MI-Each-of-1 In Stock ₹ 41,643.76

MABS826MI - Each of 1

₹ 41,643.76

In Stock

Quantity

1

Base Price: ₹ 41,643.76

GST (18%): ₹ 7,495.877

Total Price: ₹ 49,139.637

Antigen

Rsk1

Classification

Monoclonal

Concentration

Please refer to lot specific datasheet.

Formulation

Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.

Gene Accession No.

Q15418

Immunogen

KLH-conjugated linear peptide corresponding to a sequence from the linker region between the two human Rsk1 kinase domains.

Quantity

100 μg

Research Discipline

Signaling

Gene ID (Entrez)

NP_002944

Target Species

Rat

Form

Purified

Applications

Western Blot

Clone

3G5.1

Conjugate

Unconjugated

Gene

RPS6KA1, MAPKAPK1A, RSK1

Host Species

Mouse

Purification Method

Protein G Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Test Specificity

Clone 3G5.1 target epitope sequence is present in all four human Rsk1 spliced isoforms reported by UniProt (Q15418).

Content And Storage

Stable for 1 year at 2°-8°C from date of receipt.

Isotype

IgG1 κ

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Description

  • Ribosomal protein S6 kinase alpha-1 (EC 2.7.11.1; UniProt Q15418; also known as 90kDa ribosomal protein S6 kinase 1, MAP kinase-activated protein kinase 1a, MAPK-activated protein kinase 1a, MAPKAP kinase 1a, MAPKAPK-1a, p90-RSK 1, p90RSK1, p90S6K, Ribosomal S6 kinase 1, RSK-1, S6K-alpha-1) is encoded by the RPS6KA1 (also known as MAPKAPK1A, RSK1) gene (Gene ID 6195) in human
  • Ribosomal s6 kinases (RSKs) are serine/threonine kinases that play a role in mediating Mek1/2-Erk1/2 mitogen-activated protein (MAP) kinase pathway signaling events
  • There exist two types of RSKs, p70rsk (a.k.a
  • S6 Kinase or S6-H1 kinase) and p90rsk (a.k.a
  • MAPK-activated protein kinase)
  • Six p90rsk-coding genes have been identified in human, RPS6KA1 (MAPKAPK1A, RSK1), RPS6KA2 (MAPKAPK1C, RSK3), RPS6KA3 (MAPKAPK1B, RSK2), RPS6KA4 (MSK2), RPS6KA5 (MSK1), and RPS6KA6 (RSK4)
  • p90RSK1 is activated by sequential phosphorylation events, where it is first phosphorylated by Erk1/2 on the C-terminal kinase domain (CTKD) Thr573, leading to subsequent Ser380 phosphorylation in the N-terminal AGC kinase-type domain
  • Alternatively, Ser380 can be phosphorylated directly by MK2/3 independent of CTKD Thr573 phosphorylation.

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Show Difference

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MilliporeSigma™

MABS826MI

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Antigen:
Rsk1

Classification:
Monoclonal

Concentration:
Please refer to lot specific datasheet.

Formulation:
Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.

Gene Accession No.:
Q15418

Immunogen:
KLH-conjugated linear peptide corresponding to a sequence from the linker region between the two human Rsk1 kinase domains.

Quantity:
100 μg

Research Discipline:
Signaling

Gene ID (Entrez):
NP_002944

Target Species:
Rat

Form:
Purified

Applications:
Western Blot

Clone:
3G5.1

Conjugate:
Unconjugated

Gene:
RPS6KA1, MAPKAPK1A, RSK1

Host Species:
Mouse

Purification Method:
Protein G Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
Clone 3G5.1 target epitope sequence is present in all four human Rsk1 spliced isoforms reported by UniProt (Q15418).

Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.

Isotype:
IgG1 κ

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Antigen:
phospho-EGFR (Tyr1173)

Classification:
Monoclonal

Concentration:
Please refer to lot specific datasheet.

Formulation:
__

Gene Accession No.:
__

Immunogen:
KLH-conjugated linear peptide corresponding to 13 amino acids surrrounding Tyrosine 1173 of human epidermal growth factor receptor.

Quantity:
100 μL

Research Discipline:
Signaling

Gene ID (Entrez):
NP_005219

Target Species:
Human

Form:
Purified

Applications:
Immunocytochemistry, Western Blot

Clone:
3E7.2

Conjugate:
Unconjugated

Gene:
__

Host Species:
Mouse

Purification Method:
Protein G Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
__

Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.

Isotype:
IgG2b κ

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Antigen:
phospho-p70 S6 Kinase (Thr389)

Classification:
Monoclonal

Concentration:
__

Formulation:
Purified mouse monoclonal IgG2aκ in buffer containing 0.1MTris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.

Gene Accession No.:
NP_003152

Immunogen:
KLH-conjugated linear peptide corresponding to mouse p70 S6 Kinase phosphorylated at (Thr389).

Quantity:
100 μg

Research Discipline:
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Gene ID (Entrez):
__

Target Species:
Human, Mouse

Form:
Purified

Applications:
Immunocytochemistry, Western Blot

Clone:
10G7.1

Conjugate:
Unconjugated

Gene:
__

Host Species:
Mouse

Purification Method:
Protein G purified

Regulatory Status:
__

Primary or Secondary:
Primary

Test Specificity:
__

Content And Storage:
2-8°C for one year

Isotype:
IgG2a κ

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Antigen:
__

Classification:
__

Concentration:
__

Formulation:
__

Gene Accession No.:
__

Immunogen:
__

Quantity:
__

Research Discipline:
__

Gene ID (Entrez):
__

Target Species:
__

Form:
__

Applications:
__

Clone:
__

Conjugate:
__

Gene:
__

Host Species:
__

Purification Method:
__

Regulatory Status:
__

Primary or Secondary:
__

Test Specificity:
__

Content And Storage:
__

Isotype:
__