MABE644

MilliporeSigma™ Cre Recombinase, Mouse, Unlabeled, Clone: 5B4.1,

Manufacturer: MilliporeSigma™

Select a Size

Pack Size SKU Availability Price
Each of 1 MABE644-Each-of-1 In Stock ₹ 53,033.51

MABE644 - Each of 1

₹ 53,033.51

In Stock

Quantity

1

Base Price: ₹ 53,033.51

GST (18%): ₹ 9,546.032

Total Price: ₹ 62,579.542

Antigen

Cre Recombinase

Classification

Monoclonal

Concentration

Please refer to lot specific datasheet.

Formulation

Purified mouse IgG1 in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.

Gene Accession No.

P06956

Immunogen

GST-tagged recombinant Cre lacking the N-terminal region sequence.

Quantity

100 μL

Research Discipline

Epigenetics & Nuclear Function

Gene ID (Entrez)

YP_006472

Target Species

All species

Form

Purified

Applications

Western Blot

Clone

5B4.1

Conjugate

Unconjugated

Gene

cre

Host Species

Mouse

Purification Method

Protein G Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Test Specificity

Clone 5B4.1 detects an epitope outside the N-terminal region.

Content And Storage

Stable for 1 year at 2°-8°C from date of receipt.

Isotype

IgG1 κ

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Description

  • Recombinase cre (UniProt P06956) is encoded by the cre gene (Gene ID 2777477) of bacteriophage P1
  • Cre (Causes recombination with Cyclization recombinase) is a 38kDa DNA recombinase derived from the P1 bacteriophage
  • It is highly specific for a 34-bp DNA sequence motif called loxP (locus of X-over P1) found in P1 DNA
  • The loxP site is composed of a variable asymmetric 8-bp sequence in between two sets of 13-bp palindromic sequences (ATAACTTCGTATA-NNNTANNN-TATACGAAGTTAT)
  • Two cre recombinase proteins, each binds to one of the two 13-bp palindromic sequences at a loxP site, form a dimer
  • This dimer then binds to a second dimer on another loxP site to form a tetramer
  • The two sites joined by the tetramer are parallel in orientation and the double stranded DNA is cut at both loxP sites
  • The strands are then rejoined with DNA ligase
  • Because the Cre gene and loxP sites are not native to most species, they are often introduced into target cells or tissues and employed as a means to precisely control the expression of genes both in cultured cells in vitro and in animals vivo.

Compare Similar Items

Show Difference

Img

MilliporeSigma™

MABE644

--


Antigen:
Cre Recombinase

Classification:
Monoclonal

Concentration:
Please refer to lot specific datasheet.

Formulation:
Purified mouse IgG1 in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.

Gene Accession No.:
P06956

Immunogen:
GST-tagged recombinant Cre lacking the N-terminal region sequence.

Quantity:
100 μL

Research Discipline:
Epigenetics & Nuclear Function

Gene ID (Entrez):
YP_006472

Target Species:
All species

Form:
Purified

Applications:
Western Blot

Clone:
5B4.1

Conjugate:
Unconjugated

Gene:
cre

Host Species:
Mouse

Purification Method:
Protein G Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
Clone 5B4.1 detects an epitope outside the N-terminal region.

Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.

Isotype:
IgG1 κ

Img

MilliporeSigma™

MABE645MI

--


Antigen:
acetyl-Histone H3 (Lys9)

Classification:
Monoclonal

Concentration:
__

Formulation:
Rabbit monoclonal in PBS with 1% BSA and 0.09% sodium azide.

Gene Accession No.:
P84243

Immunogen:
A linear peptide corresponding to human Histone H3 acetylated at Lys9.

Quantity:
100 μg

Research Discipline:
Epigenetics and Nuclear Function

Gene ID (Entrez):
__

Target Species:
Human

Form:
Purified

Applications:
Western Blot

Clone:
RM161

Conjugate:
__

Gene:
__

Host Species:
Rabbit

Purification Method:
Protein A Purfied

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
__

Content And Storage:
Stable for one year at 2°C to 8°C from date of receipt. Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.

Isotype:
IgG

Img

MilliporeSigma™

MABE647MI

--


Antigen:
acetyl-Histone H3 (Lys27)

Classification:
Monoclonal

Concentration:
__

Formulation:
Rabbit monoclonal in PBS with 1% BSA and 0.09% sodium azide

Gene Accession No.:
P84243

Immunogen:
A linear peptide corresponding to human Histone H3 acetylated at Lys27.

Quantity:
100 μg

Research Discipline:
Epigenetics and Nuclear Function

Gene ID (Entrez):
__

Target Species:
Human

Form:
Purified

Applications:
Western Blot

Clone:
RM172

Conjugate:
__

Gene:
__

Host Species:
Rabbit

Purification Method:
Protein A Purfied

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
__

Content And Storage:
Stable for one year at 2°C to 8°C from date of receipt. Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.

Isotype:
IgG

Img

MilliporeSigma™

MABE649MI

--


Antigen:
Histone H3.3

Classification:
Monoclonal

Concentration:
__

Formulation:
Rabbit monoclonal in PBS with 1% BSA and 0.09% sodium azide.

Gene Accession No.:
P84243

Immunogen:
A peptide corresponding to human Histone H3.3.

Quantity:
100 μg

Research Discipline:
Epigenetics and Nuclear Function

Gene ID (Entrez):
__

Target Species:
Human

Form:
Purified

Applications:
Western Blot

Clone:
RM190

Conjugate:
__

Gene:
__

Host Species:
Rabbit

Purification Method:
Protein A Purfied

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
__

Content And Storage:
Stable for one year at 2°C to 8°C from date of receipt. Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.

Isotype:
IgG