MABN1529MI

MilliporeSigma™ PRICKLE2, Mouse, Unlabeled, Clone: 3B4.1,

Manufacturer: MilliporeSigma™

Select a Size

Pack Size SKU Availability Price
Each of 1 MABN1529MI-Each-of-1 In Stock ₹ 37,453.03

MABN1529MI - Each of 1

₹ 37,453.03

In Stock

Quantity

1

Base Price: ₹ 37,453.03

GST (18%): ₹ 6,741.545

Total Price: ₹ 44,194.575

Antigen

PRICKLE2

Classification

Monoclonal

Concentration

Please refer to lot specific datasheet.

Formulation

Purified mouse IgG2aκ in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.

Gene Accession No.

Q7Z3G6

Immunogen

GST-tagged recombinant human PRICKLE2 internal fragment.

Quantity

100 μg

Research Discipline

Neuroscience

Gene ID (Entrez)

NP_942559

Target Species

Human

Form

Purified

Applications

Western Blot

Clone

3B4.1

Conjugate

Unconjugated

Gene

PRICKLE2, EPM5

Host Species

Mouse

Purification Method

Protein G Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Test Specificity

Clone 3B4.1 targets an internal PRICKLE2 epitope conserved between human and murine species.

Content And Storage

Stable for 1 year at 2°-8°C from date of receipt.

Isotype

IgG2a κ

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Description

  • Prickle-like protein 2 (UniProt Q7Z3G6) is encoded by the PRICKLE2 (also known as EPM5) gene (Gene ID 166336) in human
  • Prickle2 is a nuclear membrane associated protein that belongs to a highly conserved Prickle, Espinas, Testin (PET) and Linl-1, Isl-1, and Mec-3 (LIM) domain-containing protein family
  • Prickle is part of the non-canonical Wnt signaling pathway that establishes planar cell polarity
  • It plays a critical role in neuron architecture and function
  • In mice it is shown to be highly expressed in the hippocampus region where it localizes to the post-synaptic density (PSD)
  • It interacts the PSD-95 and NMDA receptor, the two proteins implicated in Autism spectrum disorders
  • Loss of Prickle2 is known to reduce number and size of miniature synaptic currents, indicating deficits in basal synaptic transmission
  • Mice deficient in Prickle2 exhibit lower seizure threshold and PRICKLE2 mutations in humans are associated with progressive myoclonic epilepsy type 5
  • Ref.: Sowers, LP., et al.
  • (2013), Mol
  • Psychiatry
  • 18, 1077-1089.

Compare Similar Items

Show Difference

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MilliporeSigma™

MABN1529MI

--


Antigen:
PRICKLE2

Classification:
Monoclonal

Concentration:
Please refer to lot specific datasheet.

Formulation:
Purified mouse IgG2aκ in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.

Gene Accession No.:
Q7Z3G6

Immunogen:
GST-tagged recombinant human PRICKLE2 internal fragment.

Quantity:
100 μg

Research Discipline:
Neuroscience

Gene ID (Entrez):
NP_942559

Target Species:
Human

Form:
Purified

Applications:
Western Blot

Clone:
3B4.1

Conjugate:
Unconjugated

Gene:
PRICKLE2, EPM5

Host Species:
Mouse

Purification Method:
Protein G Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
Clone 3B4.1 targets an internal PRICKLE2 epitope conserved between human and murine species.

Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.

Isotype:
IgG2a κ

Img

MilliporeSigma™

MABN1537MI

--


Antigen:
TDO2

Classification:
Monoclonal

Concentration:
Please refer to lot specific datasheet.

Formulation:
Purified mouse monoclonal IgG2aκ in buffer containing 0.1M Tris-Glycine (pH 7.4) 150mM NaCl with 0.05% Sodium Azide.

Gene Accession No.:
P48775

Immunogen:
GST-tagged recombinant human TDO2 internal fragment.

Quantity:
200 μL

Research Discipline:
Neuroscience

Gene ID (Entrez):
NP_005642

Target Species:
Human

Form:
Purified

Applications:
Western Blot

Clone:
7A6.1

Conjugate:
Unconjugated

Gene:
TDO2, TDO

Host Species:
Mouse

Purification Method:
Protein G Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
Clone 7A6.1 targets an internal epitope of human and murine TDO2 (TDO).

Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.

Isotype:
IgG2a κ

Img

MilliporeSigma™

MABN1539MI

--


Antigen:
Serotonin Receptor 1B

Classification:
Monoclonal

Concentration:
Please refer to lot specific datasheet.

Formulation:
Purified mouse IgG1 in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.

Gene Accession No.:
P28222

Immunogen:
GST-tagged recombinant fragment corresponding to the thrid cytoplasmic domain of human serotonin receptor 1B.

Quantity:
100 μg

Research Discipline:
Neuroscience

Gene ID (Entrez):
NP_000854

Target Species:
Human

Form:
Purified

Applications:
Western Blot

Clone:
1C2.1

Conjugate:
Unconjugated

Gene:
HTR1B, HTR1DB

Host Species:
Mouse

Purification Method:
Protein G Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
Clone 1C2.1 targets an epitope within the third cytoplasmic domain of human, mouse, and rat serotonin receptor 1B.

Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.

Isotype:
IgG1 κ

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MilliporeSigma

MABN153MI

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Antigen:
HuC/HuD

Classification:
Monoclonal

Concentration:
__

Formulation:
Purified mouse monoclonal IgG2aκ in buffer containing 0.1MTris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.

Gene Accession No.:
NP_001411

Immunogen:
KLH-conjugated linear peptide corresponding to human HuC/HuD.

Quantity:
100 μg

Research Discipline:
__

Gene ID (Entrez):
__

Target Species:
Human, Mouse, Rat

Form:
Purified

Applications:
Immunohistochemistry, Western Blot

Clone:
15A7.1

Conjugate:
Unconjugated

Gene:
__

Host Species:
Mouse

Purification Method:
Protein G purified

Regulatory Status:
__

Primary or Secondary:
Primary

Test Specificity:
__

Content And Storage:
2-8°C for one year

Isotype:
IgG2a κ