MABE1071MI

MilliporeSigma™ BAP1, Mouse, Unlabeled, Clone: 1G8,

Manufacturer: MilliporeSigma™

Select a Size

Pack Size SKU Availability Price
Each of 1 MABE1071MI-Each-of-1 In Stock ₹ 37,453.03

MABE1071MI - Each of 1

₹ 37,453.03

In Stock

Quantity

1

Base Price: ₹ 37,453.03

GST (18%): ₹ 6,741.545

Total Price: ₹ 44,194.575

Antigen

BAP1

Classification

Monoclonal

Concentration

Please refer to lot specific datasheet.

Formulation

Purified mouse IgG1κ in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.

Gene Accession No.

Q92560

Immunogen

Recombinant full-length human BAP1.

Quantity

100 μg

Research Discipline

Epigenetics & Nuclear Function

Gene ID (Entrez)

NP_004647

Target Species

Human

Form

Purified

Applications

Western Blot

Clone

1G8

Conjugate

Unconjugated

Gene

BAP1, KIAA0272, hucep-6

Host Species

Mouse

Purification Method

Protein G Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Test Specificity

Clone 1G8 targets human BAP1 UCH domain.

Content And Storage

Stable for 1 year at 2°-8°C from date of receipt.

Isotype

IgG1 κ

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Description

  • Atlastin-1 (UniProt Q8WXF7; also known as Brain-specific GTP-binding protein, GBP-3, GTP-binding protein 3, Guanine nucleotide-binding protein 3, hGBP3, Spastic paraplegia 3 protein A) is encoded by the ATL1 (also known as GBP3, HSN1D, SPG3, SPG3A) gene (Gene ID 51062) in human
  • Atlastin-1 is a dynamin/Mx/guanylate-binding protein superfamily member with three conserved guanylate-binding/GTPase active site motifs, P-loop (a.a
  • 74-81), DxxG (a.a
  • 146-149), and RD (217-218)
  • Atlastin-1 is a multimeric integral membrane protein localized on ER and cis-Golgi apparatus and widely expressed in many tissues, including the smooth muscle, adrenal gland, kidney, testis, lung, and brain
  • Atlastin-1 interacts with the microtubule-severing ATPase spastin as well as with the DP1/Yop1p and reticulon families of ER-shaping proteins, Atlastin-1 knockdown results in decreased number of neuronal processes and impaired axon formation in cultured cortical neurons, while atlastin-1 overexpression increases total dendrite length both in vivo and in vitro
  • ALT1 gene mutations cause abnormal ER morphology and are linked to hereditary spastic paraplegias (HSPs), a genetically heterogeneous group of neurological disorders, includiing SPG3 (spastic paraplegia 3, autosomal dominan) and HSN1D (neuropathy, hereditary sensory, 1D), characterized by lower limb spasticity and weakness
  • Human atlastin-1 is a 492-amino acid protein that passes through the ER membrane twice (a.a
  • 450-470, 472-492), having both its N- and C-terminal ends at the cytoplasmic side (a.a
  • 1-449, 493-558).

Compare Similar Items

Show Difference

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MilliporeSigma™

MABE1071MI

--


Antigen:
BAP1

Classification:
Monoclonal

Concentration:
Please refer to lot specific datasheet.

Formulation:
Purified mouse IgG1κ in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.

Gene Accession No.:
Q92560

Immunogen:
Recombinant full-length human BAP1.

Quantity:
100 μg

Research Discipline:
Epigenetics & Nuclear Function

Gene ID (Entrez):
NP_004647

Target Species:
Human

Form:
Purified

Applications:
Western Blot

Clone:
1G8

Conjugate:
Unconjugated

Gene:
BAP1, KIAA0272, hucep-6

Host Species:
Mouse

Purification Method:
Protein G Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
Clone 1G8 targets human BAP1 UCH domain.

Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.

Isotype:
IgG1 κ

Img

MilliporeSigma

MABE1072MI

--


Antigen:
CtIP

Classification:
Monoclonal

Concentration:
Please refer to lot specific datasheet.

Formulation:
__

Gene Accession No.:
__

Immunogen:
GST-tagged recombinant fragment corresponding to 278 amino acids from the C-terminal half of human CtBP-interacting protein.

Quantity:
100 μg

Research Discipline:
Epigenetics and Nuclear Function

Gene ID (Entrez):
NP_002885.1

Target Species:
Human, Frog

Form:
Purified

Applications:
Western Blot, Affinity Purification, Immunohistochemistry (Paraffin)

Clone:
11-1

Conjugate:
Unconjugated

Gene:
__

Host Species:
Mouse

Purification Method:
Protein G Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
Clone 11-1 specifically detects CtBP-interacting protein in human tonsils and pancreas.

Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.

Isotype:
IgG1 κ

Img

MilliporeSigma™

MABE1073

--


Antigen:
acetyl SMC3 (Lys105/106)

Classification:
Monoclonal

Concentration:
Please refer to lot specific datasheet.

Formulation:
Purified mouse IgG2b in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.

Gene Accession No.:
Q9UQE7

Immunogen:
KLH-conjugated linear peptide corresponding to the target region sequence of human/mouse/rat SMC3 containing acetylated Lys105 and Lys106.

Quantity:
100 μL

Research Discipline:
Epigenetics & Nuclear Function

Gene ID (Entrez):
NP_005436

Target Species:
Human

Form:
Purified

Applications:
ChIP Assay, ELISA, Western Blot

Clone:
21A7

Conjugate:
Unconjugated

Gene:
SMC3, BAM, BMH, CDLS3, CSPG6, SMC3L1

Host Species:
Mouse

Purification Method:
Protein G Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
Clone 21A7 bound Lys105/106-diacetylated SMC3 peptide with 2-fold higher affinity than Lys105-monoacetylated SMC3 peptide (Kd = 0.04 and 0.09μg/mL, respectively), while displaying much reduced affinity toward Lys105-monoacetylated (Kd = 0.73μg/mL) and little affinity toward nonacetylated (Kd = 2.99μg/mL) peptide (Rahman, S., et al. (2015). Proc. Natl. Acad. Sci. U. S. A. 112(36):11270-11275).

Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.

Isotype:
IgG2b κ

Img

MilliporeSigma™

MABE1074MI

--


Antigen:
SMARCA3 (HLTF)

Classification:
Monoclonal

Concentration:
Please refer to lot specific datasheet.

Formulation:
Purified mouse IgG1 in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.

Gene Accession No.:
Q14527

Immunogen:
GST-tagged recombinant human HLTF (SMARCA3) N-terminal fragment.

Quantity:
100 μg

Research Discipline:
Epigenetics & Nuclear Function

Gene ID (Entrez):
NP_620636.1

Target Species:
Human

Form:
Purified

Applications:
Immunohistochemistry (Paraffin)

Clone:
11-1

Conjugate:
Unconjugated

Gene:
HLTF, HIP116A, RNF80, SMARCA3, SNF2L3, ZBU1

Host Species:
Mouse

Purification Method:
Protein G Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
Clone 11-1 detected predominantly nuclear HLTF immunoreactivity by immunohistochemistry staining. Clone 11-1 epitope lies within the N-terminal region present in human HLTF (SMARCA3) spliced isoform 1, but not in isoform 2 reported by UniProt (Q14527).

Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.

Isotype:
IgG1 κ