MABE1074MI
MilliporeSigma™ SMARCA3 (HLTF), Mouse, Unlabeled, Clone: 11-1,
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | MABE1074MI-Each-of-1 | In Stock | ₹ 37,453.03 |
MABE1074MI - Each of 1
In Stock
Quantity
1
Base Price: ₹ 37,453.03
GST (18%): ₹ 6,741.545
Total Price: ₹ 44,194.575
Antigen
SMARCA3 (HLTF)
Classification
Monoclonal
Concentration
Please refer to lot specific datasheet.
Formulation
Purified mouse IgG1 in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.
Q14527
Immunogen
GST-tagged recombinant human HLTF (SMARCA3) N-terminal fragment.
Quantity
100 μg
Research Discipline
Epigenetics & Nuclear Function
Gene ID (Entrez)
NP_620636.1
Target Species
Human
Form
Purified
Applications
Immunohistochemistry (Paraffin)
Clone
11-1
Conjugate
Unconjugated
Gene
HLTF, HIP116A, RNF80, SMARCA3, SNF2L3, ZBU1
Host Species
Mouse
Purification Method
Protein G Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Test Specificity
Clone 11-1 detected predominantly nuclear HLTF immunoreactivity by immunohistochemistry staining. Clone 11-1 epitope lies within the N-terminal region present in human HLTF (SMARCA3) spliced isoform 1, but not in isoform 2 reported by UniProt (Q14527).
Content And Storage
Stable for 1 year at 2°-8°C from date of receipt.
Isotype
IgG1 κ
Related Products
Description
- Helicase-like transcription factor (UniProt Q14527; also known as DNA-binding protein/plasminogen activator inhibitor 1 regulator, HIP116, RING finger protein 80, Sucrose non-fermenting protein 2-like 3, SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3) is encoded by the HLTF (also known as HIP116A, RNF80, SMARCA3, SNF2L3, ZBU1) gene (Gene ID 6596) in human
- Helicase-like transcription factor (115kDa)is a SWI/SNF (mating-type switching/sucrose non-fermenting) protein that uses ATP hydrolysis to remodel chromatin in multiple cellular processes
- It is shown to regulate transcription by binding to the SV40 enhancer and the promoters Serpin E1 and HIV-1
- It is well expressed in brain, heart, kidney, liver, lung, pancreas, placenta, and skeletal muscle
- It was initially characterized for its DNA binding and transcriptional activity, however, later was shown to act as an E3 ubiquitin ligase and was implicated in post-replication DNA repair by polyubiquitination of proliferating cell nuclear antigen (PCNA)
- The inactivation of HIP116 is shown to induce an elevated level of chromosome breaks and fusions in mouse embryonic fibroblasts after treatment with alkylating agents
- HIP116 inactivation in transgenic mice is reported to disrupt cell cycle at the G2/M phase.
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Antigen: SMARCA3 (HLTF)
Classification: Monoclonal
Concentration: Please refer to lot specific datasheet.
Formulation: Purified mouse IgG1 in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.: Q14527
Immunogen: GST-tagged recombinant human HLTF (SMARCA3) N-terminal fragment.
Quantity: 100 μg
Research Discipline: Epigenetics & Nuclear Function
Gene ID (Entrez): NP_620636.1
Target Species: Human
Form: Purified
Applications: Immunohistochemistry (Paraffin)
Clone: 11-1
Conjugate: Unconjugated
Gene: HLTF, HIP116A, RNF80, SMARCA3, SNF2L3, ZBU1
Host Species: Mouse
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Clone 11-1 detected predominantly nuclear HLTF immunoreactivity by immunohistochemistry staining. Clone 11-1 epitope lies within the N-terminal region present in human HLTF (SMARCA3) spliced isoform 1, but not in isoform 2 reported by UniProt (Q14527).
Content And Storage: Stable for 1 year at 2°-8°C from date of receipt.
Isotype: IgG1 κ
Antigen:
SMARCA3 (HLTF)
Classification:
Monoclonal
Concentration:
Please refer to lot specific datasheet.
Formulation:
Purified mouse IgG1 in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.:
Q14527
Immunogen:
GST-tagged recombinant human HLTF (SMARCA3) N-terminal fragment.
Quantity:
100 μg
Research Discipline:
Epigenetics & Nuclear Function
Gene ID (Entrez):
NP_620636.1
Target Species:
Human
Form:
Purified
Applications:
Immunohistochemistry (Paraffin)
Clone:
11-1
Conjugate:
Unconjugated
Gene:
HLTF, HIP116A, RNF80, SMARCA3, SNF2L3, ZBU1
Host Species:
Mouse
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Clone 11-1 detected predominantly nuclear HLTF immunoreactivity by immunohistochemistry staining. Clone 11-1 epitope lies within the N-terminal region present in human HLTF (SMARCA3) spliced isoform 1, but not in isoform 2 reported by UniProt (Q14527).
Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.
Isotype:
IgG1 κ
Antigen: __
Classification: __
Concentration: __
Formulation: __
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Immunogen: __
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Target Species: __
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Purification Method: __
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Primary or Secondary: __
Test Specificity: __
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Antigen: TAF10/TAFII30
Classification: Monoclonal
Concentration: Please refer to lot specific datasheet.
Formulation: Mouse monoclonal IgG1κ ascites with 0.05% Sodium Azide.
Gene Accession No.: Q12962
Immunogen: Ovalbumin-conjugated linear peptide corresponding to the N-terminal sequence of human TAF10/TAFII30.
Quantity: 100 μL
Research Discipline: Epigenetics & Nuclear Function
Gene ID (Entrez): NP_006275
Target Species: Human
Form: Ascites
Applications: Immunocytochemistry, Immunoprecipitation, Western Blot
Clone: 23TA-1H8
Conjugate: Unconjugated
Gene: TAF10, TAF2A, TAF2H, TAFII30
Host Species: Mouse
Purification Method: Unpurified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Clone 23TA-1H8 (a.k.a. 1H8, 23TA 1H8, 23TA1H8) recognizes an N-terminal epitope present in human (UniProt Q12962), but not mouse (UniProt Q8K0H5), TAF10 (TAFII30) sequence.
Content And Storage: Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Isotype: IgG1 κ
Antigen:
TAF10/TAFII30
Classification:
Monoclonal
Concentration:
Please refer to lot specific datasheet.
Formulation:
Mouse monoclonal IgG1κ ascites with 0.05% Sodium Azide.
Gene Accession No.:
Q12962
Immunogen:
Ovalbumin-conjugated linear peptide corresponding to the N-terminal sequence of human TAF10/TAFII30.
Quantity:
100 μL
Research Discipline:
Epigenetics & Nuclear Function
Gene ID (Entrez):
NP_006275
Target Species:
Human
Form:
Ascites
Applications:
Immunocytochemistry, Immunoprecipitation, Western Blot
Clone:
23TA-1H8
Conjugate:
Unconjugated
Gene:
TAF10, TAF2A, TAF2H, TAFII30
Host Species:
Mouse
Purification Method:
Unpurified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Clone 23TA-1H8 (a.k.a. 1H8, 23TA 1H8, 23TA1H8) recognizes an N-terminal epitope present in human (UniProt Q12962), but not mouse (UniProt Q8K0H5), TAF10 (TAFII30) sequence.
Content And Storage:
Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Isotype:
IgG1 κ
Antigen: TAF10/TAFII30
Classification: Monoclonal
Concentration: Please refer to lot specific datasheet.
Formulation: Mouse monoclonal IgG1κ ascites with 0.05% Sodium Azide.
Gene Accession No.: Q12962
Immunogen: Recombinant human TAF10/TAFII30.
Quantity: 100 μL
Research Discipline: Epigenetics & Nuclear Function
Gene ID (Entrez): NP_006275
Target Species: Human
Form: Ascites
Applications: Immunoprecipitation, Western Blot
Clone: 6TA-2B11
Conjugate: Unconjugated
Gene: TAF10, TAF2A, TAF2H, TAFII30
Host Species: Mouse
Purification Method: Unpurified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Clone 6TA-2B11 (a.k.a. 6TA 2B11) specifically immunostained wild-type, but not Taf10-/-, mouse embryonic blastocysts (Mohan, W.S. Jr, et al. (2003). Mol .Cell. Biol. 23(12):4307-4318).
Content And Storage: Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Isotype: IgG1 κ
Antigen:
TAF10/TAFII30
Classification:
Monoclonal
Concentration:
Please refer to lot specific datasheet.
Formulation:
Mouse monoclonal IgG1κ ascites with 0.05% Sodium Azide.
Gene Accession No.:
Q12962
Immunogen:
Recombinant human TAF10/TAFII30.
Quantity:
100 μL
Research Discipline:
Epigenetics & Nuclear Function
Gene ID (Entrez):
NP_006275
Target Species:
Human
Form:
Ascites
Applications:
Immunoprecipitation, Western Blot
Clone:
6TA-2B11
Conjugate:
Unconjugated
Gene:
TAF10, TAF2A, TAF2H, TAFII30
Host Species:
Mouse
Purification Method:
Unpurified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Clone 6TA-2B11 (a.k.a. 6TA 2B11) specifically immunostained wild-type, but not Taf10-/-, mouse embryonic blastocysts (Mohan, W.S. Jr, et al. (2003). Mol .Cell. Biol. 23(12):4307-4318).
Content And Storage:
Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Isotype:
IgG1 κ