MABE1107MI
MilliporeSigma™ SMARCA3 (HLTF), Mouse, Unlabeled, Clone: 5-1,
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | MABE1107MI-Each-of-1 | In Stock | ₹ 38,734.72 |
MABE1107MI - Each of 1
In Stock
Quantity
1
Base Price: ₹ 38,734.72
GST (18%): ₹ 6,972.25
Total Price: ₹ 45,706.97
Antigen
SMARCA3 (HLTF)
Classification
Monoclonal
Concentration
Please refer to lot specific datasheet.
Formulation
Purified mouse IgG1 in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.
Q14527
Immunogen
GST-tagged recombinant human HLTF (SMARCA3) N-terminal fragment.
Quantity
100 μg
Research Discipline
Epigenetics & Nuclear Function
Gene ID (Entrez)
NP_620636.1
Target Species
Human
Form
Purified
Applications
Immunohistochemistry (Paraffin)
Clone
5-1
Conjugate
Unconjugated
Gene
HLTF, HIP116A, RNF80, SMARCA3, SNF2L3, ZBU1
Host Species
Mouse
Purification Method
Protein G Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Test Specificity
Clone 5-1 detected predominantly nuclear HLTF (SMARCA3) immunoreactivity by immunohistochemistry staining. Clone 5-1 epitope lies within an N-terminal region present in both spliced isoforms of human HLTF reported by UniProt (Q14527).
Content And Storage
Stable for 1 year at 2°-8°C from date of receipt.
Isotype
IgG1 κ
Related Products
Description
- Helicase-like transcription factor (UniProt Q14527; also known as DNA-binding protein/plasminogen activator inhibitor 1 regulator, HIP116, RING finger protein 80, Sucrose non-fermenting protein 2-like 3, SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 3) is encoded by the HLTF (also known as HIP116A, RNF80, SMARCA3, SNF2L3, ZBU1) gene (Gene ID 6596) in human
- Helicase-like transcription factor (115kDa)is a SWI/SNF (mating-type switching/sucrose non-fermenting) protein that uses ATP hydrolysis to remodel chromatin in multiple cellular processes
- It is shown to regulate transcription by binding to the SV40 enhancer and the promoters Serpin E1 and HIV-1
- It is well expressed in brain, heart, kidney, liver, lung, pancreas, placenta, and skeletal muscle
- It was initially characterized for its DNA binding and transcriptional activity, however, later was shown to act as an E3 ubiquitin ligase and was implicated in post-replication DNA repair by polyubiquitination of proliferating cell nuclear antigen (PCNA)
- The inactivation of HIP116 is shown to induce an elevated level of chromosome breaks and fusions in mouse embryonic fibroblasts after treatment with alkylating agents
- HIP116 inactivation in transgenic mice is reported to disrupt cell cycle at the G2/M phase.
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Antigen: SMARCA3 (HLTF)
Classification: Monoclonal
Concentration: Please refer to lot specific datasheet.
Formulation: Purified mouse IgG1 in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.: Q14527
Immunogen: GST-tagged recombinant human HLTF (SMARCA3) N-terminal fragment.
Quantity: 100 μg
Research Discipline: Epigenetics & Nuclear Function
Gene ID (Entrez): NP_620636.1
Target Species: Human
Form: Purified
Applications: Immunohistochemistry (Paraffin)
Clone: 5-1
Conjugate: Unconjugated
Gene: HLTF, HIP116A, RNF80, SMARCA3, SNF2L3, ZBU1
Host Species: Mouse
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Clone 5-1 detected predominantly nuclear HLTF (SMARCA3) immunoreactivity by immunohistochemistry staining. Clone 5-1 epitope lies within an N-terminal region present in both spliced isoforms of human HLTF reported by UniProt (Q14527).
Content And Storage: Stable for 1 year at 2°-8°C from date of receipt.
Isotype: IgG1 κ
Antigen:
SMARCA3 (HLTF)
Classification:
Monoclonal
Concentration:
Please refer to lot specific datasheet.
Formulation:
Purified mouse IgG1 in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.:
Q14527
Immunogen:
GST-tagged recombinant human HLTF (SMARCA3) N-terminal fragment.
Quantity:
100 μg
Research Discipline:
Epigenetics & Nuclear Function
Gene ID (Entrez):
NP_620636.1
Target Species:
Human
Form:
Purified
Applications:
Immunohistochemistry (Paraffin)
Clone:
5-1
Conjugate:
Unconjugated
Gene:
HLTF, HIP116A, RNF80, SMARCA3, SNF2L3, ZBU1
Host Species:
Mouse
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Clone 5-1 detected predominantly nuclear HLTF (SMARCA3) immunoreactivity by immunohistochemistry staining. Clone 5-1 epitope lies within an N-terminal region present in both spliced isoforms of human HLTF reported by UniProt (Q14527).
Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.
Isotype:
IgG1 κ
Antigen: __
Classification: __
Concentration: __
Formulation: __
Gene Accession No.: __
Immunogen: __
Quantity: __
Research Discipline: __
Gene ID (Entrez): __
Target Species: __
Form: __
Applications: __
Clone: __
Conjugate: __
Gene: __
Host Species: __
Purification Method: __
Regulatory Status: __
Primary or Secondary: __
Test Specificity: __
Content And Storage: __
Isotype: __
Antigen:
__
Classification:
__
Concentration:
__
Formulation:
__
Gene Accession No.:
__
Immunogen:
__
Quantity:
__
Research Discipline:
__
Gene ID (Entrez):
__
Target Species:
__
Form:
__
Applications:
__
Clone:
__
Conjugate:
__
Gene:
__
Host Species:
__
Purification Method:
__
Regulatory Status:
__
Primary or Secondary:
__
Test Specificity:
__
Content And Storage:
__
Isotype:
__
Antigen: HHV-8 LNA-1
Classification: Monoclonal
Concentration: Please refer to lot specific datasheet.
Formulation: Purified rat monoclonal IgG2c in buffer containing 0.1M Tris-Glycine (pH 7.4) 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.: Q9DUM3;Q9QR71
Immunogen: Affinity-purified GST fusions of HHV-8 LNA-1 C-terminal fragments (Kellam, P., et al. (1999). J. Virol. 73(6): 5149 5155).
Quantity: 100 μg
Research Discipline: Epigenetics & Nuclear Function
Gene ID (Entrez): AAD46501.1;YP_001129431
Target Species: Human
Form: Purified
Applications: Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Immunoprecipitation
Clone: LN53
Conjugate: Unconjugated
Gene: ORF73
Host Species: Rat
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Clone LN53 recognizes repetitive glutamic acid structural motifs EQEQE and EPEPE found in the Glu-rich repeat region of human Kaposi's sarcoma-associated herpesvirus (KSHV or HHV-8) and simian retroperitoneal fibromatosis herpesvirus (RFHV) Orf73 latency-associated nuclear antigen (LANA or LNA), respectively.
Content And Storage: Stable for 1 year at 2°-8°C from date of receipt.
Isotype: IgG2c κ
Antigen:
HHV-8 LNA-1
Classification:
Monoclonal
Concentration:
Please refer to lot specific datasheet.
Formulation:
Purified rat monoclonal IgG2c in buffer containing 0.1M Tris-Glycine (pH 7.4) 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.:
Q9DUM3;Q9QR71
Immunogen:
Affinity-purified GST fusions of HHV-8 LNA-1 C-terminal fragments (Kellam, P., et al. (1999). J. Virol. 73(6): 5149 5155).
Quantity:
100 μg
Research Discipline:
Epigenetics & Nuclear Function
Gene ID (Entrez):
AAD46501.1;YP_001129431
Target Species:
Human
Form:
Purified
Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Immunoprecipitation
Clone:
LN53
Conjugate:
Unconjugated
Gene:
ORF73
Host Species:
Rat
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Clone LN53 recognizes repetitive glutamic acid structural motifs EQEQE and EPEPE found in the Glu-rich repeat region of human Kaposi's sarcoma-associated herpesvirus (KSHV or HHV-8) and simian retroperitoneal fibromatosis herpesvirus (RFHV) Orf73 latency-associated nuclear antigen (LANA or LNA), respectively.
Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.
Isotype:
IgG2c κ
Antigen: FOXA2
Classification: Monoclonal
Concentration: __
Formulation: Purified mouse monoclonal IgG1κ in buffer containing 0.1MTris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Accession No.: NP_068556
Immunogen: Recombinant protein corresponding to the human FOXA2.
Quantity: 200 μL
Research Discipline: __
Gene ID (Entrez): __
Target Species: Human
Form: Purified
Applications: Western Blot
Clone: 3C10
Conjugate: Unconjugated
Gene: __
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: __
Primary or Secondary: Primary
Test Specificity: __
Content And Storage: 2-8°C for one year
Isotype: IgG1 κ
Antigen:
FOXA2
Classification:
Monoclonal
Concentration:
__
Formulation:
Purified mouse monoclonal IgG1κ in buffer containing 0.1MTris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Accession No.:
NP_068556
Immunogen:
Recombinant protein corresponding to the human FOXA2.
Quantity:
200 μL
Research Discipline:
__
Gene ID (Entrez):
__
Target Species:
Human
Form:
Purified
Applications:
Western Blot
Clone:
3C10
Conjugate:
Unconjugated
Gene:
__
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
__
Primary or Secondary:
Primary
Test Specificity:
__
Content And Storage:
2-8°C for one year
Isotype:
IgG1 κ