MABF1083MI
MilliporeSigma™ IFIT5, Mouse, Unlabeled, Clone: 10A12.1,
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | MABF1083MI-Each-of-1 | In Stock | ₹ 38,673.12 |
MABF1083MI - Each of 1
In Stock
Quantity
1
Base Price: ₹ 38,673.12
GST (18%): ₹ 6,961.162
Total Price: ₹ 45,634.282
Antigen
IFIT5
Classification
Monoclonal
Concentration
Please refer to lot specific datasheet.
Formulation
Purified mouse IgG1 in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.
Q13325
Immunogen
GST-tagged recombinant human IFIT5 fragment encompassing TPR repeats 6 and 8.
Quantity
100 μL
Research Discipline
Inflammation & Immunology
Gene ID (Entrez)
NP_036552
Target Species
Human
Form
Purified
Applications
Western Blot
Clone
10A12.1
Conjugate
Unconjugated
Gene
IFIT5, ISG58, RI58
Host Species
Mouse
Purification Method
Protein G Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Test Specificity
Clone 10A12.1 epitope lies within region encompassing TPR repeats 6 and 8 present in both spliced isoforms of human IFIT5 reported by UniProt (Q13325).
Content And Storage
Stable for 1 year at 2°-8°C from date of receipt.
Isotype
IgG1 κ
Related Products
Description
- Interferon-induced protein with tetratricopeptide repeats 5 (UniProt Q13325; also known as IFIT-5, Interferon-induced 58kDa protein, P58, Retinoic acid- and interferon-inducible 58kDa protein) is encoded by the IFIT5 (also known as ISG58, RI58) gene (Gene ID 24138) in human
- IFIT1, IFIT2, IFIT3, and IFIT5 constitute the family of interferon-stimulated genes (ISGs) that are induced in response to virus infection, stimulation by interferons (IFNs) or double-stranded RNA (dsRNA)
- The protiens encoded by IFIT1 and IFIT2 are called ISG56 (p56) and ISG54 (p54) in both human and murine species, while the murine IFIT3 (ISG49 or p49) is of a different size than its human counterpart (ISG60 or p60) and no known murine IFIT5 analog exists
- IFIT family proteins restrict virus replication by various means
- IFIT1 is known to disrupt complex formation between eIF3 and HCV RNA and inhibit HPV E1 helicase
- IFIT3 is shown to enhance TBK1 and MAVS interation to potentiate antiviral response
- IFIT5 is reported to facilitate the interaction between I B kinase (IKK) and TGF- -activated kinase 1 (TAK1) by binding both proteins, resulting in enhanced NF- B activation as a reuslt of increased IKK phosphorylation and activation
- In addition, both IFIT1 and IFIT5 are shown to recognize viral RNA carrying 5 -triphosphate (PPP-RNA)
- Human IFIT5 contains eight tetratricopeptide repeat (TPR) helix-turn-helix motifs (a.a
- 51-84, 94-127, 138-173, 181-214, 249-282, 338-371, 376-410, 435-468), with a.a
- 254-260 within TPR repeat 5 mediating PPP-RNA interaction.
Compare Similar Items
Show Difference
Antigen: IFIT5
Classification: Monoclonal
Concentration: Please refer to lot specific datasheet.
Formulation: Purified mouse IgG1 in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.: Q13325
Immunogen: GST-tagged recombinant human IFIT5 fragment encompassing TPR repeats 6 and 8.
Quantity: 100 μL
Research Discipline: Inflammation & Immunology
Gene ID (Entrez): NP_036552
Target Species: Human
Form: Purified
Applications: Western Blot
Clone: 10A12.1
Conjugate: Unconjugated
Gene: IFIT5, ISG58, RI58
Host Species: Mouse
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Clone 10A12.1 epitope lies within region encompassing TPR repeats 6 and 8 present in both spliced isoforms of human IFIT5 reported by UniProt (Q13325).
Content And Storage: Stable for 1 year at 2°-8°C from date of receipt.
Isotype: IgG1 κ
Antigen:
IFIT5
Classification:
Monoclonal
Concentration:
Please refer to lot specific datasheet.
Formulation:
Purified mouse IgG1 in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.:
Q13325
Immunogen:
GST-tagged recombinant human IFIT5 fragment encompassing TPR repeats 6 and 8.
Quantity:
100 μL
Research Discipline:
Inflammation & Immunology
Gene ID (Entrez):
NP_036552
Target Species:
Human
Form:
Purified
Applications:
Western Blot
Clone:
10A12.1
Conjugate:
Unconjugated
Gene:
IFIT5, ISG58, RI58
Host Species:
Mouse
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Clone 10A12.1 epitope lies within region encompassing TPR repeats 6 and 8 present in both spliced isoforms of human IFIT5 reported by UniProt (Q13325).
Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.
Isotype:
IgG1 κ
Antigen: hnRNP A2B1
Classification: Monoclonal
Concentration: Please refer to lot specific datasheet.
Formulation: __
Gene Accession No.: __
Immunogen: KLH-conjugated linear peptide corresponding to 15 amino acids from the N-terminal region of human heterogeneous nuclear ribonucleoproteins A2/B1.
Quantity: 100 μL
Research Discipline: Inflammation and Immunology
Gene ID (Entrez): NP_112533
Target Species: Human, Mouse
Form: Purified
Applications: Western Blot, Immunohistochemistry (Paraffin)
Clone: 12B12.2
Conjugate: Unconjugated
Gene: __
Host Species: Mouse
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Clone 12B12.2 specifically detects heterogeneous nuclear ribonucleoproteins A2/B1. it targets an epitope within 15 amino acids from the N-terminal region.
Content And Storage: Stable for 1 year at 2-8°C from date of receipt.
Isotype: IgG1 κ
Antigen:
hnRNP A2B1
Classification:
Monoclonal
Concentration:
Please refer to lot specific datasheet.
Formulation:
__
Gene Accession No.:
__
Immunogen:
KLH-conjugated linear peptide corresponding to 15 amino acids from the N-terminal region of human heterogeneous nuclear ribonucleoproteins A2/B1.
Quantity:
100 μL
Research Discipline:
Inflammation and Immunology
Gene ID (Entrez):
NP_112533
Target Species:
Human, Mouse
Form:
Purified
Applications:
Western Blot, Immunohistochemistry (Paraffin)
Clone:
12B12.2
Conjugate:
Unconjugated
Gene:
__
Host Species:
Mouse
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Clone 12B12.2 specifically detects heterogeneous nuclear ribonucleoproteins A2/B1. it targets an epitope within 15 amino acids from the N-terminal region.
Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.
Isotype:
IgG1 κ
Antigen: DAG Kinase Alpha
Classification: Monoclonal
Concentration: Please refer to lot specific datasheet.
Formulation: __
Gene Accession No.: __
Immunogen: GST/His-tagged recombinant fragment corresponding to the first 110 amino acids of human DAG kinase alpha.
Quantity: 25 μg
Research Discipline: Inflammation and Immunology
Gene ID (Entrez): __
Target Species: Human
Form: Purified
Applications: Western Blot, Immunohistochemistry (Paraffin)
Clone: __
Conjugate: Unconjugated
Gene: __
Host Species: Mouse
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Clone 10D6.1 detects DAG kinase alpha in human. It targets an epitope within the first 110 amino acids from the N-terminal region.
Content And Storage: Stable for 1 year at 2-8°C from date of receipt.
Isotype: IgG2a
Antigen:
DAG Kinase Alpha
Classification:
Monoclonal
Concentration:
Please refer to lot specific datasheet.
Formulation:
__
Gene Accession No.:
__
Immunogen:
GST/His-tagged recombinant fragment corresponding to the first 110 amino acids of human DAG kinase alpha.
Quantity:
25 μg
Research Discipline:
Inflammation and Immunology
Gene ID (Entrez):
__
Target Species:
Human
Form:
Purified
Applications:
Western Blot, Immunohistochemistry (Paraffin)
Clone:
__
Conjugate:
Unconjugated
Gene:
__
Host Species:
Mouse
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Clone 10D6.1 detects DAG kinase alpha in human. It targets an epitope within the first 110 amino acids from the N-terminal region.
Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.
Isotype:
IgG2a
Antigen: __
Classification: __
Concentration: __
Formulation: __
Gene Accession No.: __
Immunogen: __
Quantity: __
Research Discipline: __
Gene ID (Entrez): __
Target Species: __
Form: __
Applications: __
Clone: __
Conjugate: __
Gene: __
Host Species: __
Purification Method: __
Regulatory Status: __
Primary or Secondary: __
Test Specificity: __
Content And Storage: __
Isotype: __
Antigen:
__
Classification:
__
Concentration:
__
Formulation:
__
Gene Accession No.:
__
Immunogen:
__
Quantity:
__
Research Discipline:
__
Gene ID (Entrez):
__
Target Species:
__
Form:
__
Applications:
__
Clone:
__
Conjugate:
__
Gene:
__
Host Species:
__
Purification Method:
__
Regulatory Status:
__
Primary or Secondary:
__
Test Specificity:
__
Content And Storage:
__
Isotype:
__