MABE1079MI

MilliporeSigma™ TAF10/TAFII30, Mouse, Unlabeled, Clone: 6TA-2B11,

Manufacturer: MilliporeSigma™

Select a Size

Pack Size SKU Availability Price
Each of 1 MABE1079MI-Each-of-1 In Stock ₹ 38,734.72

MABE1079MI - Each of 1

₹ 38,734.72

In Stock

Quantity

1

Base Price: ₹ 38,734.72

GST (18%): ₹ 6,972.25

Total Price: ₹ 45,706.97

Antigen

TAF10/TAFII30

Classification

Monoclonal

Concentration

Please refer to lot specific datasheet.

Formulation

Mouse monoclonal IgG1κ ascites with 0.05% Sodium Azide.

Gene Accession No.

Q12962

Immunogen

Recombinant human TAF10/TAFII30.

Quantity

100 μL

Research Discipline

Epigenetics & Nuclear Function

Gene ID (Entrez)

NP_006275

Target Species

Human

Form

Ascites

Applications

Immunoprecipitation, Western Blot

Clone

6TA-2B11

Conjugate

Unconjugated

Gene

TAF10, TAF2A, TAF2H, TAFII30

Host Species

Mouse

Purification Method

Unpurified

Regulatory Status

RUO

Primary or Secondary

Primary

Test Specificity

Clone 6TA-2B11 (a.k.a. 6TA 2B11) specifically immunostained wild-type, but not Taf10-/-, mouse embryonic blastocysts (Mohan, W.S. Jr, et al. (2003). Mol .Cell. Biol. 23(12):4307-4318).

Content And Storage

Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.

Isotype

IgG1 κ

Related Products

Img

MilliporeSigma™

MABE1078MI

--

Img

MilliporeSigma™

MABE628MI

--

Img

MilliporeSigma™

MABE633MI

--

Img

MilliporeSigma™

MABC680MI

--

Img

MilliporeSigma™

MABS1223

--

Img

MilliporeSigma™

MAB427CMI

--

Img

MilliporeSigma™

MABS1283MI

--

Img

MilliporeSigma™

MABS1196MI

--

Description

  • Transcription initiation factor TFIID subunit 10 (UniProt Q12962; also known as STAF28, TAF(II)30, TAFII-30, TAFII30, Transcription initiation factor TFIID 30kDa subunit) is encoded by the TAF10 (also known as TAF2A, TAF2H, TAFII30) gene (Gene ID 6881) in human.Transcription initiation factor TFIID subunit 10 (UniProt Q12962; also known as STAF28, TAF(II)30, TAFII-30, TAFII30, Transcription initiation factor TFIID 30kDa subunit) is encoded by the TAF10 (also known as TAF2A, TAF2H, TAFII30) gene (Gene ID 6881) in human
  • TAF10 (TAFII30) is a subunit of both the general transcription factor (GTF) TFIID and the coactivator SAGA (Spt-Ada-Gcn5-acetyltransferase) histone acetyltransferase (HAT) complexes involved in the initiation of RNA polymerase II (Pol II) transcription in eukaryotes
  • TFIID complex is composed of the TATA-binding protein (TBP) and thirteen TBP-associated factors (TAFs) that allow its recognition of not only TATA box-containing, but also TATA-less promoters for site-specific assembly of preinitiation complex (PIC)
  • TAF10-knockout studies in mice indicate that TAF10 plays an important role during embryonic development and homeostasis in a tissue-dependent manner
  • TAF10 ablation is reported to result in severe anemia and lethality at embryonic stage E13.5 due to impaired erythropoiesis
  • In addition, TAF10 is shown to not only interact with the transcription factor GATA1, but also regulate its transcription as evidenced by its occupancy at GATA1 genomic locus in human fetal erythroid cells.

Compare Similar Items

Show Difference

Img

MilliporeSigma™

MABE1079MI

--


Antigen:
TAF10/TAFII30

Classification:
Monoclonal

Concentration:
Please refer to lot specific datasheet.

Formulation:
Mouse monoclonal IgG1κ ascites with 0.05% Sodium Azide.

Gene Accession No.:
Q12962

Immunogen:
Recombinant human TAF10/TAFII30.

Quantity:
100 μL

Research Discipline:
Epigenetics & Nuclear Function

Gene ID (Entrez):
NP_006275

Target Species:
Human

Form:
Ascites

Applications:
Immunoprecipitation, Western Blot

Clone:
6TA-2B11

Conjugate:
Unconjugated

Gene:
TAF10, TAF2A, TAF2H, TAFII30

Host Species:
Mouse

Purification Method:
Unpurified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
Clone 6TA-2B11 (a.k.a. 6TA 2B11) specifically immunostained wild-type, but not Taf10-/-, mouse embryonic blastocysts (Mohan, W.S. Jr, et al. (2003). Mol .Cell. Biol. 23(12):4307-4318).

Content And Storage:
Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.

Isotype:
IgG1 κ

Img

MilliporeSigma™

MABE1081

--


Antigen:
5-Methylcytosine (5mC)

Classification:
Monoclonal

Concentration:
Please refer to lot specific datasheet.

Formulation:
Purified mouse IgG2a in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.

Gene Accession No.:
__

Immunogen:
BSA-conjugated 5-methylcytosine (5mC).

Quantity:
100 μg

Research Discipline:
Epigenetics & Nuclear Function

Gene ID (Entrez):
__

Target Species:
All species

Form:
Purified

Applications:
Immunoprecipitation

Clone:
EDL MC-4

Conjugate:
Unconjugated

Gene:
__

Host Species:
Mouse

Purification Method:
Protein G Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
Clone EDL MC-4 targets 5-methylcytosine (5mC), but not 5-hydroxymethylcytosine (5hmC), 5-carboxylcytosine (5caC), or unmodified cytosine (C). A less than 25% cross-reactivity toward 5-formylcytosine (5fC) was observed, which has no impact on 5mC detection by clone EDL MC-4 in cell samples, where 5mC modification level is typically more than 100- to 1,000-fold of 5fC modification level.

Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.

Isotype:
IgG2a λ

Img

Sigma Aldrich

MABE1084

clone 1.1A, from mouse...


Antigen:
__

Classification:
__

Concentration:
__

Formulation:
__

Gene Accession No.:
__

Immunogen:
__

Quantity:
__

Research Discipline:
__

Gene ID (Entrez):
__

Target Species:
__

Form:
__

Applications:
__

Clone:
__

Conjugate:
__

Gene:
__

Host Species:
__

Purification Method:
__

Regulatory Status:
__

Primary or Secondary:
__

Test Specificity:
__

Content And Storage:
__

Isotype:
__

Img

MilliporeSigma™

MABE1093MI

--


Antigen:
5-Hydroxymethylcytosine (5hmC)

Classification:
Monoclonal

Concentration:
Please refer to lot specific datasheet.

Formulation:
Purified mouse IgG2b in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.

Gene Accession No.:
__

Immunogen:
BSA-conjugated 5-hydroxymethylcytidine.

Quantity:
100 μg

Research Discipline:
Epigenetics & Nuclear Function

Gene ID (Entrez):
__

Target Species:
All species

Form:
Purified

Applications:
Immunoprecipitation

Clone:
EDL HMC 1A

Conjugate:
Unconjugated

Gene:
__

Host Species:
Mouse

Purification Method:
Protein G Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
Clone EDL HMC 1A targets 5-hydroxymethylcytosine (5hmC), but not 5-methylcytosine (5mC), 5-carboxylcytosine (5caC), 5-formylcytosine (5fC), or unmodified cytosine (C).

Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.

Isotype:
IgG2b κ