MABN1834MI
MilliporeSigma™ anti-phospho-Filamin-A (Ser2152) Clone: PS2,
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | MABN1834MI-Each-of-1 | In Stock | ₹ 48,852.19 |
MABN1834MI - Each of 1
In Stock
Quantity
1
Base Price: ₹ 48,852.19
GST (18%): ₹ 8,793.394
Total Price: ₹ 57,645.584
Antigen
Filamin-A (Ser2152)
Classification
Monoclonal
Conjugate
Unconjugated
Gene Accession No.
P21333
Host Species
Mouse
Purification Method
Protein G purified
Regulatory Status
RUO
Primary or Secondary
Primary
Test Specificity
Ser2152 of human and murine Filamin-A isoform 1 (P21333-1 and Q8BTM8-1) corresponds to Ser2144 of human Filamin-A isoform 2 (P21333-2). Equivalent site is not present in murine spliced isoform 2.
Content And Storage
2°C to 8°C for one year from date of shipment
Isotype
IgG2b κ
Applications
Immunocytochemistry, Immunofluorescence, Western Blot
Clone
PS2
Formulation
Purified mouse monoclonal IgG2bκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols
FLNA, FLN, FLN1
Immunogen
KLH-conjugated linear peptide corresponding to the Filamin repeat 20 of human phospho-Filamin-A (Ser2152).
Quantity
100 μL
Research Discipline
Neuroscience
Gene ID (Entrez)
NP_001447
Target Species
Human, Mouse
Form
Purified
Related Products
Description
- Specifically detects Filamin-A (Ser2152) Clone: PS2 in Human, Mouse samples, and it is validated for Immunocytochemistry, Immunofluorescence, Western Blotting Filamin-A (UniProt P21333; also known as ABP-280, Actin binding protein 280, Alpha-filamin, Endothelial actin-binding protein, Filamin-1, FLN-A, Non-muscle filamin) is encoded by the FLNA (also known as ABP, CSBS, CVD1, FLN, FLN1, FMD, MNS, NHBP, OPD, OPD1, OPD2, XLVD, XMVD) gene (Gene ID 2316) in human
- Filamin-A (FLN-A) is an actin-binding protein essential for cytoskeletal rearrangement and cell locomotion
- Serine 2152 of FLN-A is a PKA phosphorylation target
- FLN-A S2152 phosphorylation is essential for FLN-A-mediated recruitment of signaling proteins, adhesion molecules, and the vesicle-trafficking complex to the peripheral actin rim, so as to stabilize the cortical structure and epithelial membrane
- Mutations in FLNA and ARFGEF2 genes cause periventricular heterotopia (PVH or PH), a congenital malformation of cortical development characterized by a reduced brain size and ectopic neuronal nodules along the ventricular neuroepithelium as a result of impaired initiation of neuronal migration
- Suppression of either Arfgef2 or Mekk4 results in increased cellular FLN-A level and Ser2152 phosphorylation
- In addition, Arfgef2 or Mekk4 deletion causes PVH in knockout mice.
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Antigen: Filamin-A (Ser2152)
Classification: Monoclonal
Conjugate: Unconjugated
Gene Accession No.: P21333
Host Species: Mouse
Purification Method: Protein G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Ser2152 of human and murine Filamin-A isoform 1 (P21333-1 and Q8BTM8-1) corresponds to Ser2144 of human Filamin-A isoform 2 (P21333-2). Equivalent site is not present in murine spliced isoform 2.
Content And Storage: 2°C to 8°C for one year from date of shipment
Isotype: IgG2b κ
Applications: Immunocytochemistry, Immunofluorescence, Western Blot
Clone: PS2
Formulation: Purified mouse monoclonal IgG2bκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols: FLNA, FLN, FLN1
Immunogen: KLH-conjugated linear peptide corresponding to the Filamin repeat 20 of human phospho-Filamin-A (Ser2152).
Quantity: 100 μL
Research Discipline: Neuroscience
Gene ID (Entrez): NP_001447
Target Species: Human, Mouse
Form: Purified
Antigen:
Filamin-A (Ser2152)
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene Accession No.:
P21333
Host Species:
Mouse
Purification Method:
Protein G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Ser2152 of human and murine Filamin-A isoform 1 (P21333-1 and Q8BTM8-1) corresponds to Ser2144 of human Filamin-A isoform 2 (P21333-2). Equivalent site is not present in murine spliced isoform 2.
Content And Storage:
2°C to 8°C for one year from date of shipment
Isotype:
IgG2b κ
Applications:
Immunocytochemistry, Immunofluorescence, Western Blot
Clone:
PS2
Formulation:
Purified mouse monoclonal IgG2bκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols:
FLNA, FLN, FLN1
Immunogen:
KLH-conjugated linear peptide corresponding to the Filamin repeat 20 of human phospho-Filamin-A (Ser2152).
Quantity:
100 μL
Research Discipline:
Neuroscience
Gene ID (Entrez):
NP_001447
Target Species:
Human, Mouse
Form:
Purified
Antigen: AGE
Classification: Monoclonal
Conjugate: Unconjugated
Gene Accession No.: __
Host Species: Mouse
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Clone 6C7 specifically reacts with carboxymethyl lysine modified proteins.
Content And Storage: Stable for 1 year at 2-8°C from date of receipt.
Isotype: IgG2a κ
Applications: Immunohistochemistry (Paraffin)
Clone: 6C7
Formulation: __
Gene Symbols: __
Immunogen: Carboxymethyl Lysine modified Keyhole Limpet Hemocyanin (KLH).
Quantity: 100 μg
Research Discipline: Neuroscience
Gene ID (Entrez): __
Target Species: Mouse
Form: Purified
Antigen:
AGE
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene Accession No.:
__
Host Species:
Mouse
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Clone 6C7 specifically reacts with carboxymethyl lysine modified proteins.
Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.
Isotype:
IgG2a κ
Applications:
Immunohistochemistry (Paraffin)
Clone:
6C7
Formulation:
__
Gene Symbols:
__
Immunogen:
Carboxymethyl Lysine modified Keyhole Limpet Hemocyanin (KLH).
Quantity:
100 μg
Research Discipline:
Neuroscience
Gene ID (Entrez):
__
Target Species:
Mouse
Form:
Purified
Antigen: Neuritin (CPG15)
Classification: Monoclonal
Conjugate: Unconjugated
Gene Accession No.: __
Host Species: Mouse
Purification Method: Protein G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Clone A6.1 detects human and rat Neuritin.
Content And Storage: Stable for 1 year at 2-8°C from date of receipt.
Isotype: IgG2b κ
Applications: Western Blot
Clone: A6.1
Formulation: Purified mouse monoclonal antibody IgG2b in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Gene Symbols: NRN1;NRN
Immunogen: GST-tagged full-length human recombinant Neuritin.
Quantity: 100 μg
Research Discipline: Neuroscience
Gene ID (Entrez): NP_001265639
Target Species: Human, Rat
Form: Purified
Antigen:
Neuritin (CPG15)
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene Accession No.:
__
Host Species:
Mouse
Purification Method:
Protein G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Clone A6.1 detects human and rat Neuritin.
Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.
Isotype:
IgG2b κ
Applications:
Western Blot
Clone:
A6.1
Formulation:
Purified mouse monoclonal antibody IgG2b in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Gene Symbols:
NRN1;NRN
Immunogen:
GST-tagged full-length human recombinant Neuritin.
Quantity:
100 μg
Research Discipline:
Neuroscience
Gene ID (Entrez):
NP_001265639
Target Species:
Human, Rat
Form:
Purified
Antigen: Neuritin (CPG15)
Classification: Monoclonal
Conjugate: Unconjugated
Gene Accession No.: __
Host Species: Mouse
Purification Method: Protein G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Clone A6.1 detects human and rat Neuritin.
Content And Storage: Stable for 1 year at 2-8°C from date of receipt.
Isotype: IgG2b κ
Applications: Western Blot
Clone: A6.1
Formulation: Purified mouse monoclonal antibody IgG2b in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Gene Symbols: NRN1;NRN
Immunogen: GST-tagged full-length human recombinant Neuritin.
Quantity: 25 μg
Research Discipline: Neuroscience
Gene ID (Entrez): NP_001265639
Target Species: Human, Rat
Form: Purified
Antigen:
Neuritin (CPG15)
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene Accession No.:
__
Host Species:
Mouse
Purification Method:
Protein G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Clone A6.1 detects human and rat Neuritin.
Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.
Isotype:
IgG2b κ
Applications:
Western Blot
Clone:
A6.1
Formulation:
Purified mouse monoclonal antibody IgG2b in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Gene Symbols:
NRN1;NRN
Immunogen:
GST-tagged full-length human recombinant Neuritin.
Quantity:
25 μg
Research Discipline:
Neuroscience
Gene ID (Entrez):
NP_001265639
Target Species:
Human, Rat
Form:
Purified