MABT345MI
MilliporeSigma™ anti-Prelamin-A Clone: 7G11,
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | MABT345MI-Each-of-1 | In Stock | ₹ 41,306.66 |
MABT345MI - Each of 1
In Stock
Quantity
1
Base Price: ₹ 41,306.66
GST (18%): ₹ 7,435.199
Total Price: ₹ 48,741.859
Antigen
Prelamin-A
Classification
Monoclonal
Conjugate
Unconjugated
Gene Accession No.
P48678
Host Species
Rat
Purification Method
Protein G purified
Regulatory Status
RUO
Primary or Secondary
Primary
Test Specificity
Clone 7G11 detects prelamin-A regardless of its farnesylation state, but not mature Lamin-A (a.a. 1-647) lacking the C-terminal propeptide sequence. Clone 7G11 does not detect the pre- or mature forms of the spliced isoforms C1 & C2 (Lamin-C; P48678-2 and P48678-3).
Content And Storage
2°C to 8°C for one year from date of shipment
Isotype
IgG2a κ
Applications
Immunofluorescence, Western Blot
Clone
7G11
Formulation
Purified rat monoclonal IgG2aκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols
Lmna, Lmn1
Immunogen
Linear peptide corresponding to the C-terminal propeptide sequence of mouse Prelamin-A.
Quantity
100 μg
Research Discipline
Cell Structure
Gene ID (Entrez)
NP_001002011
Target Species
Mouse
Form
Purified
Related Products
Description
- Specifically detects Prelamin-A Clone: 7G11 in Mouse samples, and it is validated for Immunofluorescence, Western Blotting Lamin-A is a key component of the nuclear lamina, a protein network underlying the inner membrane that determines nuclear shape and size
- The same gene (Lmna, Dhe, or Lamn1 in murine species; Gene ID 16905) that encodes lamin-A also codes for the alternatively spliced prelamin-C isoforms (UniProt P48678-2 and P48678-3)
- Murine lamin-A (UniProt P48678-1) is initially produced as a 665-amino acid prelamin A that terminals in a CAAX motif
- It is further processed post-translationally by four enzymatic steps to yield the mature Lamin-A
- Farnesylation of Cys662, endoproteolytic cleavage of the last three amino acids (a.a
- 663-665), carboxylmethylation of Cys662, and the final endoproteolytic removal of the remaining propeptide sequence (a.a
- 648-662), including the farnesylated Cys662, is catalyzed by the ER membrane zinc metalloproteinase ZMPSTE24.
Compare Similar Items
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Antigen: Prelamin-A
Classification: Monoclonal
Conjugate: Unconjugated
Gene Accession No.: P48678
Host Species: Rat
Purification Method: Protein G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Clone 7G11 detects prelamin-A regardless of its farnesylation state, but not mature Lamin-A (a.a. 1-647) lacking the C-terminal propeptide sequence. Clone 7G11 does not detect the pre- or mature forms of the spliced isoforms C1 & C2 (Lamin-C; P48678-2 and P48678-3).
Content And Storage: 2°C to 8°C for one year from date of shipment
Isotype: IgG2a κ
Applications: Immunofluorescence, Western Blot
Clone: 7G11
Formulation: Purified rat monoclonal IgG2aκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols: Lmna, Lmn1
Immunogen: Linear peptide corresponding to the C-terminal propeptide sequence of mouse Prelamin-A.
Quantity: 100 μg
Research Discipline: Cell Structure
Gene ID (Entrez): NP_001002011
Target Species: Mouse
Form: Purified
Antigen:
Prelamin-A
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene Accession No.:
P48678
Host Species:
Rat
Purification Method:
Protein G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Clone 7G11 detects prelamin-A regardless of its farnesylation state, but not mature Lamin-A (a.a. 1-647) lacking the C-terminal propeptide sequence. Clone 7G11 does not detect the pre- or mature forms of the spliced isoforms C1 & C2 (Lamin-C; P48678-2 and P48678-3).
Content And Storage:
2°C to 8°C for one year from date of shipment
Isotype:
IgG2a κ
Applications:
Immunofluorescence, Western Blot
Clone:
7G11
Formulation:
Purified rat monoclonal IgG2aκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols:
Lmna, Lmn1
Immunogen:
Linear peptide corresponding to the C-terminal propeptide sequence of mouse Prelamin-A.
Quantity:
100 μg
Research Discipline:
Cell Structure
Gene ID (Entrez):
NP_001002011
Target Species:
Mouse
Form:
Purified
Antigen: Integrin alpha6
Classification: Monoclonal
Conjugate: __
Gene Accession No.: P23229
Host Species: Mouse
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: __
Content And Storage: Stable for one year at 2°C to 8°C from date of receipt.
Isotype: IgG1 κ
Applications: Immunohistochemistry (Paraffin), Western Blot
Clone: 6H7.1
Formulation: Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols: ITGA6
Immunogen: KLH-conjugated linear peptide corresponding to the cytoplasmic region of human Integrin alpha6 isoforms 2/4/6/7/9.
Quantity: 100 μg
Research Discipline: Cell Structure
Gene ID (Entrez): NP_000201
Target Species: Human
Form: Purified
Antigen:
Integrin alpha6
Classification:
Monoclonal
Conjugate:
__
Gene Accession No.:
P23229
Host Species:
Mouse
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
__
Content And Storage:
Stable for one year at 2°C to 8°C from date of receipt.
Isotype:
IgG1 κ
Applications:
Immunohistochemistry (Paraffin), Western Blot
Clone:
6H7.1
Formulation:
Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols:
ITGA6
Immunogen:
KLH-conjugated linear peptide corresponding to the cytoplasmic region of human Integrin alpha6 isoforms 2/4/6/7/9.
Quantity:
100 μg
Research Discipline:
Cell Structure
Gene ID (Entrez):
NP_000201
Target Species:
Human
Form:
Purified
Antigen: Mastl
Classification: Monoclonal
Conjugate: Unconjugated
Gene Accession No.: NP_001165774
Host Species: Mouse
Purification Method: Protein G purified
Regulatory Status: __
Primary or Secondary: Primary
Test Specificity: __
Content And Storage: 2-8°C for one year
Isotype: IgG1 κ
Applications: Immunohistochemistry, Western Blot
Clone: 4F9
Formulation: Purified mouse monoclonal IgG1κ in buffer containing 0.1MTris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols: MASTL, GW, GWL, THC2
Immunogen: Recombinant protein corresponding to the C-terminus of human Mastl.
Quantity: 100 μg
Research Discipline: __
Gene ID (Entrez): __
Target Species: Human
Form: Purified
Antigen:
Mastl
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene Accession No.:
NP_001165774
Host Species:
Mouse
Purification Method:
Protein G purified
Regulatory Status:
__
Primary or Secondary:
Primary
Test Specificity:
__
Content And Storage:
2-8°C for one year
Isotype:
IgG1 κ
Applications:
Immunohistochemistry, Western Blot
Clone:
4F9
Formulation:
Purified mouse monoclonal IgG1κ in buffer containing 0.1MTris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols:
MASTL, GW, GWL, THC2
Immunogen:
Recombinant protein corresponding to the C-terminus of human Mastl.
Quantity:
100 μg
Research Discipline:
__
Gene ID (Entrez):
__
Target Species:
Human
Form:
Purified
Antigen: Ero1
Classification: Monoclonal
Conjugate: Unconjugated
Gene Accession No.: NP_055399
Host Species: Mouse
Purification Method: Protein G purified
Regulatory Status: __
Primary or Secondary: Primary
Test Specificity: __
Content And Storage: 2-8°C for one year
Isotype: IgG2a κ
Applications: Immunofluorescence, Immunoprecipitation, Western Blot
Clone: 2G4/12
Formulation: Purified mouse monoclonal IgG2aκ in buffer containing 0.1MTris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols: ERO1L
Immunogen: GST-tagged recombinant protein corresponding to Human Ero1.
Quantity: 100 μg
Research Discipline: __
Gene ID (Entrez): __
Target Species: Human, Mouse, Rat
Form: Purified
Antigen:
Ero1
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene Accession No.:
NP_055399
Host Species:
Mouse
Purification Method:
Protein G purified
Regulatory Status:
__
Primary or Secondary:
Primary
Test Specificity:
__
Content And Storage:
2-8°C for one year
Isotype:
IgG2a κ
Applications:
Immunofluorescence, Immunoprecipitation, Western Blot
Clone:
2G4/12
Formulation:
Purified mouse monoclonal IgG2aκ in buffer containing 0.1MTris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols:
ERO1L
Immunogen:
GST-tagged recombinant protein corresponding to Human Ero1.
Quantity:
100 μg
Research Discipline:
__
Gene ID (Entrez):
__
Target Species:
Human, Mouse, Rat
Form:
Purified