MABN184025
Neuritin (CPG15), Mouse anti-Human, Rat, Clone: A6.1, Millipore Sigma™
Manufacturer: Fischer Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | MABN184025-Each-of-1 | In Stock | ₹ 16,456.61 |
MABN184025 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 16,456.61
GST (18%): ₹ 2,962.19
Total Price: ₹ 19,418.80
Antigen
Neuritin (CPG15)
Classification
Monoclonal
Conjugate
Unconjugated
Gene Alias
candidate plasticity gene 15;CPG15
Host Species
Mouse
Purification Method
Protein G purified
Regulatory Status
RUO
Primary or Secondary
Primary
Test Specificity
Clone A6.1 detects human and rat Neuritin.
Content And Storage
Stable for 1 year at 2-8°C from date of receipt.
Isotype
IgG2b κ
Applications
Western Blot
Clone
A6.1
Formulation
Purified mouse monoclonal antibody IgG2b in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Gene Symbols
NRN1;NRN
Immunogen
GST-tagged full-length human recombinant Neuritin.
Quantity
25 μg
Research Discipline
Neuroscience
Gene ID (Entrez)
NP_001265639
Target Species
Human, Rat
Form
Purified
Related Products
Description
- Anti-Neuritin (CPG15), clone A6.1, Cat
- No
- MABN1840, is a highly specific mouse monoclonal antibody that targets Neuritin and has been tested for use in Western Blotting
- Neuritin (UniProt: Q9NPD7) is encoded by the NRN1 (also known as NRN) gene (Gene ID: 51299) in human
- Neuritin, a conserved, glycosylphosphatidylinositol (GPI)-anchored protein that plays a role in the development, survival and function of neurons
- Its activity is induced by brain-derived neurotrophic factor (BDNF) and neurotrophin-3 (NT-3)
- It is highly expressed by induced and natural regulatory T cells (TREGs)
- It also promotes the maintenance of the TREGs pool by stabilizing Foxp3 expression and promoting the persistence of these cells
- Deficiency of Neuritin is shown to result in an imbalance between central and peripheral TREG populations and functions
- Neuritin has a wide variety of effects in the nervous system, such as promoting neurite outgrowth, modulating neurite outgrowth during neuronal differentiation, and protecting motor neuron axons
- It can also promote dendritic growth, regulate synaptic plasticity, and stabilize active synapses, and promote synaptic maturation
- Its expression in the hippocampus is shown to be induced by neuronal activity following chemical- or electrical-induced seizures, ischemia, and exercise
- Chronic antidepressant treatment is reported to increase neuritin expression in rat brain
- Neuritin is synthesized with a signal peptide (aa 1-27) and a propeptide (aa 28-116) that are cleaved off in the mature form (aa 117-142)
- (Ref.: Son, H., et al
- (2012)
- Proc
- Natl
- Acad
- Sci
- USA
- 109(28); 11378-83; Zhou, S., and Zhou, J (2014)
- Curr
- Med
- Chem
- 21(10); 1212-19)
- Note: A6.1 hybridoma clone, and WT/KO validation, courtesy of Lauren Makuch and Dr
- Elly Nedivi, Massachusetts Institute of Technology
- Note: A6.1 hybridoma clone, and WT/KO validation, courtesy of Dr
- Lauren Makuch and Dr
- Elly Nedivi, Massachusetts Institute of Technology.
Compare Similar Items
Show Difference
Antigen: Neuritin (CPG15)
Classification: Monoclonal
Conjugate: Unconjugated
Gene Alias: candidate plasticity gene 15;CPG15
Host Species: Mouse
Purification Method: Protein G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Clone A6.1 detects human and rat Neuritin.
Content And Storage: Stable for 1 year at 2-8°C from date of receipt.
Isotype: IgG2b κ
Applications: Western Blot
Clone: A6.1
Formulation: Purified mouse monoclonal antibody IgG2b in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Gene Symbols: NRN1;NRN
Immunogen: GST-tagged full-length human recombinant Neuritin.
Quantity: 25 μg
Research Discipline: Neuroscience
Gene ID (Entrez): NP_001265639
Target Species: Human, Rat
Form: Purified
Antigen:
Neuritin (CPG15)
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene Alias:
candidate plasticity gene 15;CPG15
Host Species:
Mouse
Purification Method:
Protein G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Clone A6.1 detects human and rat Neuritin.
Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.
Isotype:
IgG2b κ
Applications:
Western Blot
Clone:
A6.1
Formulation:
Purified mouse monoclonal antibody IgG2b in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Gene Symbols:
NRN1;NRN
Immunogen:
GST-tagged full-length human recombinant Neuritin.
Quantity:
25 μg
Research Discipline:
Neuroscience
Gene ID (Entrez):
NP_001265639
Target Species:
Human, Rat
Form:
Purified
Antigen: TRPM1
Classification: Monoclonal
Conjugate: __
Gene Alias: __
Host Species: Mouse
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: __
Content And Storage: Stable for one year at 2°C to 8°C from date of receipt.
Isotype: IgG2b κ
Applications: Western Blot
Clone: 545H5
Formulation: Purified mouse monoclonal IgG2bκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols: Trpm1; CSNB1C; Ltrpc1; Mlsn1; MLSN1
Immunogen: Detergent stabilized, C-terminal 1D4 tag-tagged recombinant full-length mouse TRPM1.
Quantity: 100 μg
Research Discipline: Neuroscience
Gene ID (Entrez): NM_001039104.2
Target Species: Mouse
Form: Purified
Antigen:
TRPM1
Classification:
Monoclonal
Conjugate:
__
Gene Alias:
__
Host Species:
Mouse
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
__
Content And Storage:
Stable for one year at 2°C to 8°C from date of receipt.
Isotype:
IgG2b κ
Applications:
Western Blot
Clone:
545H5
Formulation:
Purified mouse monoclonal IgG2bκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols:
Trpm1; CSNB1C; Ltrpc1; Mlsn1; MLSN1
Immunogen:
Detergent stabilized, C-terminal 1D4 tag-tagged recombinant full-length mouse TRPM1.
Quantity:
100 μg
Research Discipline:
Neuroscience
Gene ID (Entrez):
NM_001039104.2
Target Species:
Mouse
Form:
Purified
Antigen: SET (I2PP2A), NT
Classification: Monoclonal
Conjugate: Unconjugated
Gene Alias: __
Host Species: Mouse
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Clone 10E7 detected both full-length human SET (I2PP2A) and the N-terminal fragment I2NTF generated by Asn endopeptidase (AEP) cleavage (Basurto-Islas, G., et al. (2013). J. Biol. Chem. 288(24):17495-17507).
Content And Storage: Stable for 1 year at 2°-8°C from date of receipt.
Isotype: IgG2a κ
Applications: Western Blot
Clone: 10E7
Formulation: Purified mouse IgG2a in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Symbols: __
Immunogen: Recombinant human SET (I2PP2A).
Quantity: 100 μg
Research Discipline: Neuroscience
Gene ID (Entrez): NP_001116293
Target Species: Human
Form: Purified
Antigen:
SET (I2PP2A), NT
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene Alias:
__
Host Species:
Mouse
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Clone 10E7 detected both full-length human SET (I2PP2A) and the N-terminal fragment I2NTF generated by Asn endopeptidase (AEP) cleavage (Basurto-Islas, G., et al. (2013). J. Biol. Chem. 288(24):17495-17507).
Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.
Isotype:
IgG2a κ
Applications:
Western Blot
Clone:
10E7
Formulation:
Purified mouse IgG2a in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Symbols:
__
Immunogen:
Recombinant human SET (I2PP2A).
Quantity:
100 μg
Research Discipline:
Neuroscience
Gene ID (Entrez):
NP_001116293
Target Species:
Human
Form:
Purified
Antigen: Synapsin-1
Classification: Monoclonal
Conjugate: Unconjugated
Gene Alias: __
Host Species: Mouse
Purification Method: Purified by ion-exchange chromatography
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: __
Content And Storage: 2°C to 8°C for one year from date of shipment
Isotype: IgG2b κ
Applications: Immunocytochemistry, Western Blot
Clone: MEGS3-10A
Formulation: Purified mouse monoclonal IgG2bκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols: Syn1, Syn-1
Immunogen: Recombinant full-length mouse synapsin-1.
Quantity: 100 μL
Research Discipline: Neuroscience
Gene ID (Entrez): NP_038708.3
Target Species: Mouse
Form: Purified
Antigen:
Synapsin-1
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene Alias:
__
Host Species:
Mouse
Purification Method:
Purified by ion-exchange chromatography
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
__
Content And Storage:
2°C to 8°C for one year from date of shipment
Isotype:
IgG2b κ
Applications:
Immunocytochemistry, Western Blot
Clone:
MEGS3-10A
Formulation:
Purified mouse monoclonal IgG2bκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols:
Syn1, Syn-1
Immunogen:
Recombinant full-length mouse synapsin-1.
Quantity:
100 μL
Research Discipline:
Neuroscience
Gene ID (Entrez):
NP_038708.3
Target Species:
Mouse
Form:
Purified