MABN1847MI

MilliporeSigma™ anti-Synapsin-1 Clone: MEGS3-10A,

Manufacturer: MilliporeSigma™

Select a Size

Pack Size SKU Availability Price
Each of 1 MABN1847MI-Each-of-1 In Stock ₹ 53,734.25

MABN1847MI - Each of 1

₹ 53,734.25

In Stock

Quantity

1

Base Price: ₹ 53,734.25

GST (18%): ₹ 9,672.165

Total Price: ₹ 63,406.415

Antigen

Synapsin-1

Classification

Monoclonal

Conjugate

Unconjugated

Gene Accession No.

O88935

Host Species

Mouse

Purification Method

Purified by ion-exchange chromatography

Regulatory Status

RUO

Primary or Secondary

Primary

Target Species

Mouse

Form

Purified

Applications

Immunocytochemistry, Western Blot

Clone

MEGS3-10A

Formulation

Purified mouse monoclonal IgG2bκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.

Gene Symbols

Syn1, Syn-1

Immunogen

Recombinant full-length mouse synapsin-1.

Quantity

100 μL

Research Discipline

Neuroscience

Gene ID (Entrez)

NP_038708.3

Content And Storage

2°C to 8°C for one year from date of shipment

Isotype

IgG2b κ

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Description

  • Specifically detects Synapsin-1 Clone: MEGS3-10A in Mouse samples, and it is validated for Immunocytochemistry, Western Blotting Synapsin-1 (UniProt O88935; also known as Synapsin I) is encoded by the Syn1 (also known as Syn-1) gene (Gene ID 20964) in murine species
  • The synapins constitute a family of abundant neuronal phosphoproteins that regulate SV trafficking and neurotransmitter release at the pre-synaptic terminal
  • Three genes exisit in mammals, encoding altogether 11 synapsin members by alternative splicings (Synapsin Ia & Ib by SYN1, Synapsin IIa & IIb by SYN2, Synapsin IIIa through IIIf by SYN3), Syn III is the most precociously expressed isoform that has a role in the early phases of neural development and is downregulated in mature neurons
  • On the other hand, Syn I and Syn II are expressed at low levels at birth and their expressions progressively increase during synaptogenesis to reach a stable plateau at 1-2 months of life
  • The NH2-terminal region is divided in A, B, and C domains and is highly conserved among synapsin isoforms
  • Synapsins are regulated by postransloational phosphorylations
  • Domain A contains PKA and CaMKI/IV phosphorylation sites, domain B contains MAPK/Erk phosphorylation sites, and domain C is phosphorylated by Src
  • The c-terminal regions contain spliced domains and diverge among synapsin isoforms (domain D in Syn Ia and Ib, domain G in Syn Iia and Iib, domain H in Syn Iia, and domain J in Syn IIIa), although they all bear proline-rich regions binding to several SH3-containing proteins and additional phosphorylation sites for CaMKII, MAPK/Erk, and cdk1/5.

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MilliporeSigma™

MABN1847MI

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Antigen:
Synapsin-1

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene Accession No.:
O88935

Host Species:
Mouse

Purification Method:
Purified by ion-exchange chromatography

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Mouse

Form:
Purified

Applications:
Immunocytochemistry, Western Blot

Clone:
MEGS3-10A

Formulation:
Purified mouse monoclonal IgG2bκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.

Gene Symbols:
Syn1, Syn-1

Immunogen:
Recombinant full-length mouse synapsin-1.

Quantity:
100 μL

Research Discipline:
Neuroscience

Gene ID (Entrez):
NP_038708.3

Content And Storage:
2°C to 8°C for one year from date of shipment

Isotype:
IgG2b κ

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MABN1848

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Antigen:
DYRK1A

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene Accession No.:
Q63470

Host Species:
Mouse

Purification Method:
Protein G Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human

Form:
Purified

Applications:
Western Blot

Clone:
8D9

Formulation:
Purified mouse IgG1κ in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.

Gene Symbols:
__

Immunogen:
His-tagged recombinant rat DYRK1A N-terminal fragment.

Quantity:
100 μL

Research Discipline:
Neuroscience

Gene ID (Entrez):
NP_036923

Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.

Isotype:
IgG1 κ

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MABN1853

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Antigen:
Neuregulin-2

Classification:
Monoclonal

Conjugate:
Unconjugated

Gene Accession No.:
P56974

Host Species:
Mouse

Purification Method:
Protein G Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human

Form:
Purified

Applications:
Immunofluorescence, Immunohistochemistry (Paraffin)

Clone:
8D11

Formulation:
Purified mouse IgG1κ in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.

Gene Symbols:
__

Immunogen:
Recombinant mouse mature Neuregulin-2.

Quantity:
200 μL

Research Discipline:
Neuroscience

Gene ID (Entrez):
NP_001161363

Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.

Isotype:
IgG1 κ

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MABN1861

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Antigen:
Kallikrein 8/KLK8

Classification:
Monoclonal

Conjugate:
__

Gene Accession No.:
O60259

Host Species:
Mouse

Purification Method:
Protein G Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Form:
Purified

Applications:
Functional Assay, ELISA, Immunohistochemistry (Paraffin), Western Blot

Clone:
19-10

Formulation:
Purified mouse monoclonal IgG1κ antibody in 0.1M sodium bicarbonate buffer, pH 8.2 with 0.02% sodium azide.

Gene Symbols:
KLK8; NP; NRPN; PRSS19; TADG14

Immunogen:
Recombinant full-length human kallikrein 8.

Quantity:
100 μg

Research Discipline:
Neuroscience

Gene ID (Entrez):
NP_009127.1

Content And Storage:
Stable for one year at 2°C to 8°C from date of receipt.

Isotype:
IgG1 κ