MABS482MI
MilliporeSigma™ Mouse anti-PL Scramblase 1, Clone: 1A8,
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | MABS482MI-Each-of-1 | In Stock | ₹ 34,965.81 |
MABS482MI - Each of 1
In Stock
Quantity
1
Base Price: ₹ 34,965.81
GST (18%): ₹ 6,293.846
Total Price: ₹ 41,259.656
Antigen
PL Scramblase 1
Classification
Monoclonal
Formulation
Purified mouse monoclonal IgG2bκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols
PLSCR1
Immunogen
Recombinant protein corresponding to human PL Scramblase 1.
Quantity
100 μg
Research Discipline
Signaling
Gene ID (Entrez)
NP_066928
Content And Storage
Stable for one year at 2°C to 8°C from date of receipt.
Isotype
IgG2b κ
Applications
Immunohistochemistry, Immunoprecipitation, Western Blot
Clone
1A8
Gene Accession No.
O15162
Host Species
Mouse
Purification Method
Protein G Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Target Species
Human, Mouse
Form
Purified
Related Products
Description
- Specifically detects PL Scramblase 1 clone: 1A8 in Human, Mouse samples, and it is validated for Immunohistochemistry, Immunoprecipitation, Western Blotting Phospholipid scramblase 1 (UniProt O15162; also known as Ca 2+ -dependent phospholipid scramblase 1, Erythrocyte phospholipid scramblase, MmTRA1b, PL scramblase 1) is encoded by the PLSCR1 (also known as MMTRA1B) gene (Gene ID 5359) in human
- Plasma membrane phospholipids are distributed asymmetrically between the inner and outer leaflets
- Such asymmetrical distribution collapses in response to blood coagulation and apoptosis, resulting in phospholipid 'scrambling' between the two leaflets of the plasma membrane
- Flippases, floppases, and scramblases are three types enzymes known to mediate transbilayer lipid motion
- Flippases and floppases function via ATP-dependent mechanism, while scramblases mediate transbilayer movement in a non-selective and energy-independent manner
- Originally identified in 1996 as a 37kDa erythrocyte type II transmembrane protein that mediates calcium-dependent membrane phospholipids redistribution, PL Scramblase 1 is the protein product encoded by the founding member of the PLSCR family of genes (PLSCR1-5)
- All PLSCR family members, with the exception of PLSCR2, possess a proline-rich N-terminal region containing PxxP and PPxY domains, a cysteine-rich region, a conserved calcium-binding domain (EF-hand-like), and a putative transmembrane region enriched in hydrophobic amino acids
- In addition, PLSCR1 contains a nuclear localization signal (NLS) and a DNA-binding domain that are essential for its nuclear localization and associated nuclear function
- In addition to PLSCRs, TMEM16 and XKR family members have also been reported to mediate scramblase activity.
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Antigen: PL Scramblase 1
Classification: Monoclonal
Formulation: Purified mouse monoclonal IgG2bκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols: PLSCR1
Immunogen: Recombinant protein corresponding to human PL Scramblase 1.
Quantity: 100 μg
Research Discipline: Signaling
Gene ID (Entrez): NP_066928
Content And Storage: Stable for one year at 2°C to 8°C from date of receipt.
Isotype: IgG2b κ
Applications: Immunohistochemistry, Immunoprecipitation, Western Blot
Clone: 1A8
Gene Accession No.: O15162
Host Species: Mouse
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human, Mouse
Form: Purified
Antigen:
PL Scramblase 1
Classification:
Monoclonal
Formulation:
Purified mouse monoclonal IgG2bκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols:
PLSCR1
Immunogen:
Recombinant protein corresponding to human PL Scramblase 1.
Quantity:
100 μg
Research Discipline:
Signaling
Gene ID (Entrez):
NP_066928
Content And Storage:
Stable for one year at 2°C to 8°C from date of receipt.
Isotype:
IgG2b κ
Applications:
Immunohistochemistry, Immunoprecipitation, Western Blot
Clone:
1A8
Gene Accession No.:
O15162
Host Species:
Mouse
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Form:
Purified
Antigen: __
Classification: __
Formulation: __
Gene Symbols: __
Immunogen: __
Quantity: __
Research Discipline: __
Gene ID (Entrez): __
Content And Storage: __
Isotype: __
Applications: __
Clone: __
Gene Accession No.: __
Host Species: __
Purification Method: __
Regulatory Status: __
Primary or Secondary: __
Target Species: __
Form: __
Antigen:
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Classification:
__
Formulation:
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Gene Symbols:
__
Immunogen:
__
Quantity:
__
Research Discipline:
__
Gene ID (Entrez):
__
Content And Storage:
__
Isotype:
__
Applications:
__
Clone:
__
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__
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__
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Form:
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Antigen: Ido1
Classification: Monoclonal
Formulation: Purified mouse monoclonal IgG2aκ in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols: IDO1; IDO; INDO
Immunogen: Recombinant protein corresponding to mouse Ido1.
Quantity: 100 μg
Research Discipline: Signaling
Gene ID (Entrez): NP_002155
Content And Storage: Stable for one year at 2°C to 8°C from date of receipt.
Isotype: IgG2a κ
Applications: Flow Cytometry, Western Blot
Clone: 8G11
Gene Accession No.: P14902
Host Species: Mouse
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Mouse
Form: Purified
Antigen:
Ido1
Classification:
Monoclonal
Formulation:
Purified mouse monoclonal IgG2aκ in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols:
IDO1; IDO; INDO
Immunogen:
Recombinant protein corresponding to mouse Ido1.
Quantity:
100 μg
Research Discipline:
Signaling
Gene ID (Entrez):
NP_002155
Content And Storage:
Stable for one year at 2°C to 8°C from date of receipt.
Isotype:
IgG2a κ
Applications:
Flow Cytometry, Western Blot
Clone:
8G11
Gene Accession No.:
P14902
Host Species:
Mouse
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Mouse
Form:
Purified
Antigen: LRP-2/Megalin
Classification: Monoclonal
Formulation: Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols: LRP2, DBS
Immunogen: GST-tagged recombinant protein corresponding to the LDL-receptor class A repeats 19-21 of human LRP-2/Megalin.
Quantity: 100 μg
Research Discipline: Signaling
Gene ID (Entrez): NP_004516
Content And Storage: 2°C to 8°C for one year from date of shipment
Isotype: IgG1 κ
Applications: Immunohistochemistry (Paraffin), Western Blot
Clone: 10D5.1
Gene Accession No.: P98164
Host Species: Mouse
Purification Method: Protein G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human
Form: Purified
Antigen:
LRP-2/Megalin
Classification:
Monoclonal
Formulation:
Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols:
LRP2, DBS
Immunogen:
GST-tagged recombinant protein corresponding to the LDL-receptor class A repeats 19-21 of human LRP-2/Megalin.
Quantity:
100 μg
Research Discipline:
Signaling
Gene ID (Entrez):
NP_004516
Content And Storage:
2°C to 8°C for one year from date of shipment
Isotype:
IgG1 κ
Applications:
Immunohistochemistry (Paraffin), Western Blot
Clone:
10D5.1
Gene Accession No.:
P98164
Host Species:
Mouse
Purification Method:
Protein G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Human
Form:
Purified