MABF933MI
MilliporeSigma™ anti-SAMHD1 Clone: I19-18,
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | MABF933MI-Each-of-1 | In Stock | ₹ 40,292.08 |
MABF933MI - Each of 1
In Stock
Quantity
1
Base Price: ₹ 40,292.08
GST (18%): ₹ 7,252.574
Total Price: ₹ 47,544.654
Antigen
SAMHD1
Classification
Monoclonal
Conjugate
Unconjugated
Gene Accession No.
Q9Y3Z3
Host Species
Mouse
Purification Method
Protein G purified
Regulatory Status
RUO
Primary or Secondary
Primary
Target Species
Human
Form
Purified
Applications
Flow Cytometry, Immunocytochemistry, Western Blot
Clone
I19-18
Formulation
Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols
SAMHD1, CHBL2, HDDC1, MOP5, SBBI88
Immunogen
GST-tagged recombinant full-length human SAMHD1.
Quantity
100 μg
Research Discipline
Inflammation, Immunology
Gene ID (Entrez)
NP_056289
Content And Storage
2°C to 8°C for one year from date of shipment
Isotype
IgG1 κ
Related Products
Description
- Specifically detects SAMHD1 Clone: I19-18 in Human samples, and it is validated for Flow Cytometry, Immunocytochemistry, Western Blotting Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 (UniProt Q9Y3Z3; also known as DCIP, Dendritic cell-derived IFNG-induced protein, dNTPase, Monocyte protein 5, MOP-5, SAM domain and HD domain-containing protein 1) is encoded by the SAMHD1 (also known as CHBL2, HDDC1, MOP5, SBBI88) gene (Gene ID 25939) in human
- The sterile alpha motif domain and histidine-aspartate domain-containing protein 1 (SAMHD1) is a dGTP/GTP-activated deoxynucleotide (dNTP) triphosphohydrolase regulated by Cyclin A2/CDK1-dependent phosphorylation and is involved in balancing cellular dNTP pools
- SAMHD1 was originally identified as a disease gene associated with the rare infantile encephalopathy Aicardi-Goutières syndrome
- SAMHD1 was later shown to restrict HIV-1 replication in non-dividing myeloid-lineage cells and resting T cells by reducing the cellular dNTP concentration
- Simian immunodeficiency viruses (SIVs) are found to use their Vpx/Vpr accessory proteins to engage and modify host Cullin-RING-type E3 ubiquitin ligases substrate recognition to target SAMHD1 for poly-ubiquitylation and subsequent proteasomal degradation.
Compare Similar Items
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Antigen: SAMHD1
Classification: Monoclonal
Conjugate: Unconjugated
Gene Accession No.: Q9Y3Z3
Host Species: Mouse
Purification Method: Protein G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human
Form: Purified
Applications: Flow Cytometry, Immunocytochemistry, Western Blot
Clone: I19-18
Formulation: Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols: SAMHD1, CHBL2, HDDC1, MOP5, SBBI88
Immunogen: GST-tagged recombinant full-length human SAMHD1.
Quantity: 100 μg
Research Discipline: Inflammation, Immunology
Gene ID (Entrez): NP_056289
Content And Storage: 2°C to 8°C for one year from date of shipment
Isotype: IgG1 κ
Antigen:
SAMHD1
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene Accession No.:
Q9Y3Z3
Host Species:
Mouse
Purification Method:
Protein G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Human
Form:
Purified
Applications:
Flow Cytometry, Immunocytochemistry, Western Blot
Clone:
I19-18
Formulation:
Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols:
SAMHD1, CHBL2, HDDC1, MOP5, SBBI88
Immunogen:
GST-tagged recombinant full-length human SAMHD1.
Quantity:
100 μg
Research Discipline:
Inflammation, Immunology
Gene ID (Entrez):
NP_056289
Content And Storage:
2°C to 8°C for one year from date of shipment
Isotype:
IgG1 κ
Antigen: __
Classification: __
Conjugate: __
Gene Accession No.: __
Host Species: __
Purification Method: __
Regulatory Status: __
Primary or Secondary: __
Target Species: __
Form: __
Applications: __
Clone: __
Formulation: __
Gene Symbols: __
Immunogen: __
Quantity: __
Research Discipline: __
Gene ID (Entrez): __
Content And Storage: __
Isotype: __
Antigen:
__
Classification:
__
Conjugate:
__
Gene Accession No.:
__
Host Species:
__
Purification Method:
__
Regulatory Status:
__
Primary or Secondary:
__
Target Species:
__
Form:
__
Applications:
__
Clone:
__
Formulation:
__
Gene Symbols:
__
Immunogen:
__
Quantity:
__
Research Discipline:
__
Gene ID (Entrez):
__
Content And Storage:
__
Isotype:
__
Antigen: phospho-SAMHD1 (Thr592)
Classification: Monoclonal
Conjugate: Unconjugated
Gene Accession No.: __
Host Species: Mouse
Purification Method: Protein G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human
Form: Purified
Applications: Flow Cytometry, Western Blot
Clone: __
Formulation: Purified mouse monoclonal antibody IgG2a in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Gene Symbols: SAMHD1;MOP5
Immunogen: A linear peptide corresponding to 11 amino acids surrounding phosphoryalted Thr592 from the C-terminal region of huamn SAMHD1.
Quantity: 25 μL
Research Discipline: Inflammation & Immunology
Gene ID (Entrez): __
Content And Storage: Stable for 1 year at 2-8°C from date of receipt.
Isotype: IgG2a
Antigen:
phospho-SAMHD1 (Thr592)
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene Accession No.:
__
Host Species:
Mouse
Purification Method:
Protein G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Human
Form:
Purified
Applications:
Flow Cytometry, Western Blot
Clone:
__
Formulation:
Purified mouse monoclonal antibody IgG2a in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Gene Symbols:
SAMHD1;MOP5
Immunogen:
A linear peptide corresponding to 11 amino acids surrounding phosphoryalted Thr592 from the C-terminal region of huamn SAMHD1.
Quantity:
25 μL
Research Discipline:
Inflammation & Immunology
Gene ID (Entrez):
__
Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.
Isotype:
IgG2a
Antigen: MPR300/IGF-2R/CD222
Classification: Monoclonal
Conjugate: __
Gene Accession No.: P11717
Host Species: Mouse
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human
Form: Purified
Applications: Immunocytochemistry, Immunohistochemistry, Western Blot
Clone: 2C2
Formulation: Purified mouse monoclonal IgG1κ antibody in PBS without preservatives.
Gene Symbols: IGF2R; CIMPR; MPRI
Immunogen: Recombinant full-length human MPR300/IGF-2R/CD222.
Quantity: 100 μg
Research Discipline: Inflammation and Immunology
Gene ID (Entrez): NP_000867
Content And Storage: Stable for one year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles which may damage IgG and affect product performance.
Isotype: IgG1 κ
Antigen:
MPR300/IGF-2R/CD222
Classification:
Monoclonal
Conjugate:
__
Gene Accession No.:
P11717
Host Species:
Mouse
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Human
Form:
Purified
Applications:
Immunocytochemistry, Immunohistochemistry, Western Blot
Clone:
2C2
Formulation:
Purified mouse monoclonal IgG1κ antibody in PBS without preservatives.
Gene Symbols:
IGF2R; CIMPR; MPRI
Immunogen:
Recombinant full-length human MPR300/IGF-2R/CD222.
Quantity:
100 μg
Research Discipline:
Inflammation and Immunology
Gene ID (Entrez):
NP_000867
Content And Storage:
Stable for one year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles which may damage IgG and affect product performance.
Isotype:
IgG1 κ