MABS458MI

MilliporeSigma™ Mouse anti-Betacellulin, Clone: 6G10.1,

Manufacturer: MilliporeSigma™

Select a Size

Pack Size SKU Availability Price
Each of 1 MABS458MI-Each-of-1 In Stock ₹ 37,453.03

MABS458MI - Each of 1

₹ 37,453.03

In Stock

Quantity

1

Base Price: ₹ 37,453.03

GST (18%): ₹ 6,741.545

Total Price: ₹ 44,194.575

Antigen

Betacellulin

Classification

Monoclonal

Formulation

Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.

Gene Symbols

BTC

Immunogen

GST-tagged human recombinant full-length mature betacellulin.

Quantity

100 μg

Research Discipline

Signaling

Gene ID (Entrez)

NP_001720

Content And Storage

Stable for one year at 2°C to 8°C from date of receipt.

Isotype

IgG1 κ

Applications

Immunohistochemistry, Western Blot

Clone

6G10.1

Gene Accession No.

P35070

Host Species

Mouse

Purification Method

Protein G Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Target Species

Human

Form

Purified

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Description

  • Specifically detects Betacellulin clone: 6G10.1 in Human samples, and it is validated for Immunohistochemistry, Western Blotting The human BTC gene (Gene ID 685) encodes the 178 aa preprobetacellulin (UniProt P35070) protein
  • Post-translatioinal removal of the signal peptide (aa 1-31) produces probetacellulin (aa 32-178), which further matures into the 80 aa betacellulin (aa 32-111) following propeptide (aa 112-178) removal
  • Betacellulin is an EGF family growth factor with a higher affinity and specificity for ErbB1/EGFR and ErbB4
  • Betacellulin plays an important role in the development of the acute exacerbations of chronic obstructive pulmonary disease
  • Betacellulin is also reported to induce CXCL8 (IL-8) production from human lung cancer cells through EGFR–PI3K–Akt–ERK pathway activation, resulting in the recruitment of inflammatory cells in the cancer tissue and creating an inflammatory tumor microenvironment.

Compare Similar Items

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Img

MilliporeSigma™

MABS458MI

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Antigen:
Betacellulin

Classification:
Monoclonal

Formulation:
Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.

Gene Symbols:
BTC

Immunogen:
GST-tagged human recombinant full-length mature betacellulin.

Quantity:
100 μg

Research Discipline:
Signaling

Gene ID (Entrez):
NP_001720

Content And Storage:
Stable for one year at 2°C to 8°C from date of receipt.

Isotype:
IgG1 κ

Applications:
Immunohistochemistry, Western Blot

Clone:
6G10.1

Gene Accession No.:
P35070

Host Species:
Mouse

Purification Method:
Protein G Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human

Form:
Purified

Img

MilliporeSigma

MABS45MI

--


Antigen:
Annexin A1

Classification:
Monoclonal

Formulation:
Purified mouse monoclonal IgG2aκ in buffer containing 0.1MTris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.

Gene Symbols:
ANXA1, LPC1, ANX1, p35

Immunogen:
Full length recombinant protein corresponding to human Annexin A1.Material obtained from the National Cancer Institute's Clinical Proteomic Technologies for Cancer (CPTC) program

Quantity:
100 μg

Research Discipline:
__

Gene ID (Entrez):
__

Content And Storage:
2-8°C for one year

Isotype:
IgG2a κ

Applications:
Immunohistochemistry, Western Blot

Clone:
CPTC-ANXA1-2

Gene Accession No.:
NP_000691

Host Species:
Mouse

Purification Method:
Protein G

Regulatory Status:
__

Primary or Secondary:
Primary

Target Species:
Human

Form:
Purified

Img

MilliporeSigma

MABS461MI

--


Antigen:
Neutrophil Elastase

Classification:
Monoclonal

Formulation:
Purified mouse monoclonal IgG1κ in buffer containing 0.1MTris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.

Gene Symbols:
ELANE, ELA2

Immunogen:
Whole cells corresponding to human Neutrophil Elastase.

Quantity:
100 μg

Research Discipline:
__

Gene ID (Entrez):
__

Content And Storage:
2-8°C for one year

Isotype:
IgG1 κ

Applications:
Immunocytochemistry, Immunohistochemistry, Immunoprecipitation, Inhibition Assays, Radioimmune Assays (RIA)

Clone:
AHN-10

Gene Accession No.:
NP_001963.1

Host Species:
Mouse

Purification Method:
Protein G purified

Regulatory Status:
__

Primary or Secondary:
Primary

Target Species:
Human

Form:
Purified

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MABS465MI

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Antigen:
Nampt

Classification:
Monoclonal

Formulation:
Purified rat monoclonal IgG2aκ in buffer containing PBS without preservatives.

Gene Symbols:
Nampt, Pbef1

Immunogen:
Recombinant protein corresponding to mouse Nampt.

Quantity:
100 μg

Research Discipline:
__

Gene ID (Entrez):
__

Content And Storage:
−20°C in undiluted aliquots for up to 12 months. Avoid repeated freeze/thaw cycles.

Isotype:
IgG2a κ

Applications:
ELISA, Immunohistochemistry, Inhibition Assays, Western Blot

Clone:
14A5

Gene Accession No.:
NP_067499

Host Species:
Rat

Purification Method:
Protein G purified

Regulatory Status:
__

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Form:
Purified