MABF855

MilliporeSigma™ Mouse anti-CAP-18/CAMP, Clone: H7,

Manufacturer: MilliporeSigma™

Select a Size

Pack Size SKU Availability Price
Each of 1 MABF855-Each-of-1 In Stock ₹ 32,683.92

MABF855 - Each of 1

₹ 32,683.92

In Stock

Quantity

1

Base Price: ₹ 32,683.92

GST (18%): ₹ 5,883.106

Total Price: ₹ 38,567.026

Antigen

CAP-18/CAMP

Classification

Monoclonal

Formulation

Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.

Gene Symbols

CAMP; CAP18; FALL39; HSD26; LL37

Immunogen

Human cytochrome b preparation containing co-purified hCAP-18.

Quantity

100 μg

Research Discipline

Inflammation and Immunology

Gene ID (Entrez)

NP_034051

Content And Storage

Stable for one year at 2°C to 8°C from date of receipt.

Isotype

IgG1 κ

Applications

Flow Cytometry, Immunocytochemistry, Immunoprecipitation, Western Blot

Clone

H7

Gene Accession No.

P49913

Host Species

Mouse

Purification Method

Protein G Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Target Species

Human

Form

Purified

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Description

  • Specifically detects CAP-18/CAMP clone: H7 in Human samples, and it is validated for Flow Cytometry, Immunocytochemistry, Immunoprecipitation, Western Blotting Cathelicidin antimicrobial peptide (UniProt P49913; also known as 18kDa cationic antimicrobial protein, CAP-18, hCAP-18) is encoded by the CAMP (also known as CAP18, FALL39, LL37) gene (ORF HSD26; Gene ID 820) in human
  • hCAP-18 is initially translated as a precursor molecule with a signal peptide (a.a
  • 1-30) and a propeptide (a.a
  • 31-131) sequence, the removal of which yields the mature hCAP-18 (a.a
  • a.a
  • 132-173)
  • During the inflammatory response, hCAP-18 is proteolytically cleaved into the FALL-39 (a.a 132-170), which is further processed to yield the antimicrobial protein LL-37 (CAP-37; a.a
  • 134-170)
  • Neutrophils store preformed hCAP-18 within specific granules and release it into inflamed tissue as a result of granule exocytosis
  • Once released, hCAP-18 is activated by proteinase-3-mediated cleavage, a component of neutrophil primary granules
  • In addition to its microbicidal and LPS-sequestering activity, LL-37 is also involved in the regulation of innate and humoral immune responses, wound healing, and tissue repair.

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Antigen:
CAP-18/CAMP

Classification:
Monoclonal

Formulation:
Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.

Gene Symbols:
CAMP; CAP18; FALL39; HSD26; LL37

Immunogen:
Human cytochrome b preparation containing co-purified hCAP-18.

Quantity:
100 μg

Research Discipline:
Inflammation and Immunology

Gene ID (Entrez):
NP_034051

Content And Storage:
Stable for one year at 2°C to 8°C from date of receipt.

Isotype:
IgG1 κ

Applications:
Flow Cytometry, Immunocytochemistry, Immunoprecipitation, Western Blot

Clone:
H7

Gene Accession No.:
P49913

Host Species:
Mouse

Purification Method:
Protein G Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human

Form:
Purified

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Antigen:
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Classification:
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Formulation:
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Gene Symbols:
__

Immunogen:
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Research Discipline:
__

Gene ID (Entrez):
__

Content And Storage:
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Isotype:
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Regulatory Status:
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Primary or Secondary:
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Target Species:
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Antigen:
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Classification:
Monoclonal

Formulation:
Purified mouse monoclonal IgG1κ in buffer containing 0.1M Tris-Glycine (pH 7.4) 150mM NaCl with 0.05% Sodium Azide.

Gene Symbols:
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Immunogen:
Human foreskin fibroblasts.

Quantity:
100 μg

Research Discipline:
Apoptosis & Cancer

Gene ID (Entrez):
NP_001141.2

Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.

Isotype:
IgG1 κ

Applications:
Immunoassay, ELISA, Flow Cytometry, Immunoprecipitation

Clone:
BR2

Gene Accession No.:
P15144

Host Species:
Mouse

Purification Method:
Protein G Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human

Form:
Purified

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Antigen:
CD37

Classification:
Monoclonal

Formulation:
Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.

Gene Symbols:
CD37; TSPAN26

Immunogen:
Lymph node cells from a lymphoma patient.

Quantity:
100 μg

Research Discipline:
Inflammation and Immunology

Gene ID (Entrez):
NP_001765.1

Content And Storage:
Stable for one year at 2°C to 8°C from date of receipt.

Isotype:
IgG1 κ

Applications:
Flow Cytometry, Immunohistochemistry, Immunoprecipitation

Clone:
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Gene Accession No.:
P11049

Host Species:
Mouse

Purification Method:
Protein G Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human

Form:
Purified