MABT324MI
MilliporeSigma™ Mouse anti-CEACAM8, Clone: 6/40c,
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | MABT324MI-Each-of-1 | In Stock | ₹ 40,197.80 |
MABT324MI - Each of 1
In Stock
Quantity
1
Base Price: ₹ 40,197.80
GST (18%): ₹ 7,235.604
Total Price: ₹ 47,433.404
Antigen
CEACAM8
Classification
Monoclonal
Formulation
Purified mouse monoclonal IgG1κ in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols
CEACAM8; CGM6
Immunogen
Recombinant protein corresponding to the extracellular domain of human CEACAM8.
Quantity
100 μg
Research Discipline
Cell Structure
Gene ID (Entrez)
NP_001807
Content And Storage
Stable for one year at 2°C to 8°C from date of receipt.
Isotype
IgG1 κ
Applications
ELISA, Flow Cytometry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone
6/40c
Gene Accession No.
P31997
Host Species
Mouse
Purification Method
Protein G Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Target Species
Human
Form
Purified
Related Products
Description
- Specifically detects CEACAM8 clone: 6/40c in Human samples, and it is validated for ELISA, Flow Cytometry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blotting The carcinoembryonic antigen- (CEA-) related cell adhesion molecules (CEACAMs) constitute a 12-member subgroup of the CEA family of immunoglobulin-related proteins first described in 1965 (PMID 4953873)
- CEACAMs are reported to participate in diverse physiological processes, including cell adhesion, differentiation, proliferation, and survival, as well as in carcinogenesis and bacterial pathogenesis
- CEACAM molecules from neighbouring cells can interact via their respective extracellular N-terminal IgV-like domain and mediate cell-cell adhesion through trans-oligomerization
- CEACAM molecules within the same cell can also undergo transmembrane domain-mediated cis-oligomerization, an event important for sustaining downstream cellular signaling
- Athough CEACAM1 is shown to utilize its cytoplasmic domain for transducing cellular signaling, not all CEACAM members are expressed with a significant cytoplasmic domain, and others (CEACAM5/6/7/8) are GPI-anchored without even a transmembrane domain
- (PMID 4735478)
- Human CEACAM8 (also known as CEA gene family member 6, CEA-related cell adhesion molecule 8, CD66b, CD67 antigen, Non-specific crossreacting antigen NCA-95; UniProt P31997 and Q0Z7S6) is encoded by the CEACAM8 (or CGM6) gene (NCBI Gene ID 1088)
- It is a GPI-anchored CEACAM with three extracellular Ig domains
- Clone 6/40c does not cross-react with human CEACAM1/3/4/5/6/7, rat CECAM1, or mouse CEACAM1/2.
Compare Similar Items
Show Difference
Antigen: CEACAM8
Classification: Monoclonal
Formulation: Purified mouse monoclonal IgG1κ in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols: CEACAM8; CGM6
Immunogen: Recombinant protein corresponding to the extracellular domain of human CEACAM8.
Quantity: 100 μg
Research Discipline: Cell Structure
Gene ID (Entrez): NP_001807
Content And Storage: Stable for one year at 2°C to 8°C from date of receipt.
Isotype: IgG1 κ
Applications: ELISA, Flow Cytometry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone: 6/40c
Gene Accession No.: P31997
Host Species: Mouse
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human
Form: Purified
Antigen:
CEACAM8
Classification:
Monoclonal
Formulation:
Purified mouse monoclonal IgG1κ in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols:
CEACAM8; CGM6
Immunogen:
Recombinant protein corresponding to the extracellular domain of human CEACAM8.
Quantity:
100 μg
Research Discipline:
Cell Structure
Gene ID (Entrez):
NP_001807
Content And Storage:
Stable for one year at 2°C to 8°C from date of receipt.
Isotype:
IgG1 κ
Applications:
ELISA, Flow Cytometry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone:
6/40c
Gene Accession No.:
P31997
Host Species:
Mouse
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Human
Form:
Purified
Antigen: __
Classification: __
Formulation: __
Gene Symbols: __
Immunogen: __
Quantity: __
Research Discipline: __
Gene ID (Entrez): __
Content And Storage: __
Isotype: __
Applications: __
Clone: __
Gene Accession No.: __
Host Species: __
Purification Method: __
Regulatory Status: __
Primary or Secondary: __
Target Species: __
Form: __
Antigen:
__
Classification:
__
Formulation:
__
Gene Symbols:
__
Immunogen:
__
Quantity:
__
Research Discipline:
__
Gene ID (Entrez):
__
Content And Storage:
__
Isotype:
__
Applications:
__
Clone:
__
Gene Accession No.:
__
Host Species:
__
Purification Method:
__
Regulatory Status:
__
Primary or Secondary:
__
Target Species:
__
Form:
__
Antigen: CEACAM3/5
Classification: Monoclonal
Formulation: Purified mouse monoclonal IgG1κ in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Symbols: __
Immunogen: Human IgG1 Fc-tagged recombinant human CEACAM3 extracellular domain.
Quantity: 100 μg
Research Discipline: Cell Structure
Gene ID (Entrez): NP_001806
Content And Storage: Stable for 1 year at 2°-8°C from date of receipt.
Isotype: IgG1 κ
Applications: Flow Cytometry, Immunoprecipitation, Western Blot
Clone: 308/3-3
Gene Accession No.: P40198
Host Species: Mouse
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human
Form: Purified
Antigen:
CEACAM3/5
Classification:
Monoclonal
Formulation:
Purified mouse monoclonal IgG1κ in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Symbols:
__
Immunogen:
Human IgG1 Fc-tagged recombinant human CEACAM3 extracellular domain.
Quantity:
100 μg
Research Discipline:
Cell Structure
Gene ID (Entrez):
NP_001806
Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.
Isotype:
IgG1 κ
Applications:
Flow Cytometry, Immunoprecipitation, Western Blot
Clone:
308/3-3
Gene Accession No.:
P40198
Host Species:
Mouse
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Human
Form:
Purified
Antigen: DDR1 (CD167a)
Classification: Monoclonal
Formulation: Purified mouse monoclonal IgMκ in buffer containing PBS with 0.05% sodium azide.
Gene Symbols: DDR1; CAK; EDDR1; NEP; NTRK4; PTK3A; RTK6; TRKE
Immunogen: Whole cells corresponding to human DDR1 (CD167a).
Quantity: 200 μL
Research Discipline: Cell Structure
Gene ID (Entrez): NP_001189450
Content And Storage: Stable for one year at 2°C to 8°C from date of receipt.
Isotype: IgM κ
Applications: Functional Assay, Flow Cytometry
Clone: 48B3
Gene Accession No.: Q08345
Host Species: Mouse
Purification Method: Purified by Ion-Exchange Chromatography
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human
Form: Purified
Antigen:
DDR1 (CD167a)
Classification:
Monoclonal
Formulation:
Purified mouse monoclonal IgMκ in buffer containing PBS with 0.05% sodium azide.
Gene Symbols:
DDR1; CAK; EDDR1; NEP; NTRK4; PTK3A; RTK6; TRKE
Immunogen:
Whole cells corresponding to human DDR1 (CD167a).
Quantity:
200 μL
Research Discipline:
Cell Structure
Gene ID (Entrez):
NP_001189450
Content And Storage:
Stable for one year at 2°C to 8°C from date of receipt.
Isotype:
IgM κ
Applications:
Functional Assay, Flow Cytometry
Clone:
48B3
Gene Accession No.:
Q08345
Host Species:
Mouse
Purification Method:
Purified by Ion-Exchange Chromatography
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Human
Form:
Purified