MABT323MI

MilliporeSigma™ Mouse anti-CEACAM6, Clone: 1H7-4B,

Manufacturer: MilliporeSigma™

Select a Size

Pack Size SKU Availability Price
Each of 1 MABT323MI-Each-of-1 In Stock ₹ 40,486.99

MABT323MI - Each of 1

₹ 40,486.99

In Stock

Quantity

1

Base Price: ₹ 40,486.99

GST (18%): ₹ 7,287.658

Total Price: ₹ 47,774.648

Antigen

CEACAM6

Classification

Monoclonal

Formulation

Purified mouse monoclonal IgG1κ in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.

Gene Symbols

CEACAM6; NCA

Immunogen

Recombinant protein corresponding to the extracellular domain of human CEACAM6.

Quantity

100 μg

Research Discipline

Cell Structure

Gene ID (Entrez)

NP_002474

Content And Storage

Stable for one year at 2°C to 8°C from date of receipt.

Isotype

IgG1 κ

Applications

ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone

1H7-4B

Gene Accession No.

P40199

Host Species

Mouse

Purification Method

Protein G Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Target Species

Human

Form

Purified

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Description

  • Specifically detects CEACAM6 clone: 1H7-4B in Human samples, and it is validated for ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blotting The carcinoembryonic antigen- (CEA-) related cell adhesion molecules (CEACAMs) constitute a 12-member subgroup of the CEA family of immunoglobulin-related proteins first described in 1965 (PMID 4953873)
  • CEACAMs are reported to participate in diverse physiological processes, including cell adhesion, differentiation, proliferation, and survival, as well as in carcinogenesis and bacterial pathogenesis
  • CEACAM molecules from neighbouring cells can interact via their respective extracellular N-terminal IgV-like domain and mediate cell-cell adhesion through trans-oligomerization
  • CEACAM molecules within the same cell can also undergo transmembrane domain-mediated cis-oligomerization, an event important for sustaining downstream cellular signaling
  • Athough CEACAM1 is shown to utilize its cytoplasmic domain for transducing cellular signaling, not all CEACAM members are expressed with a significant cytoplasmic domain, and others (CEACAM5/6/7/8) are GPI-anchored without even a transmembrane domain
  • (PMID 4735478)
  • Human CEACAM6 (also known as CD66c, Non-specific crossreacting antigen, Normal cross-reacting antigen; UniProt P40199) is encoded by the CEACAM6 (or CEAL & NCA) gene (NCBI Gene ID 4680)
  • It is a GPI-anchored CEACAM with three extracellular Ig domains
  • Clone 1H7-4B does not cross-react with human CEACAM1/3/4/5/7/8, rat CECAM1, or mouse CEACAM1/2.

Compare Similar Items

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MilliporeSigma™

MABT323MI

--


Antigen:
CEACAM6

Classification:
Monoclonal

Formulation:
Purified mouse monoclonal IgG1κ in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.

Gene Symbols:
CEACAM6; NCA

Immunogen:
Recombinant protein corresponding to the extracellular domain of human CEACAM6.

Quantity:
100 μg

Research Discipline:
Cell Structure

Gene ID (Entrez):
NP_002474

Content And Storage:
Stable for one year at 2°C to 8°C from date of receipt.

Isotype:
IgG1 κ

Applications:
ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone:
1H7-4B

Gene Accession No.:
P40199

Host Species:
Mouse

Purification Method:
Protein G Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human

Form:
Purified

Img

MilliporeSigma™

MABT324MI

--


Antigen:
CEACAM8

Classification:
Monoclonal

Formulation:
Purified mouse monoclonal IgG1κ in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.

Gene Symbols:
CEACAM8; CGM6

Immunogen:
Recombinant protein corresponding to the extracellular domain of human CEACAM8.

Quantity:
100 μg

Research Discipline:
Cell Structure

Gene ID (Entrez):
NP_001807

Content And Storage:
Stable for one year at 2°C to 8°C from date of receipt.

Isotype:
IgG1 κ

Applications:
ELISA, Flow Cytometry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Clone:
6/40c

Gene Accession No.:
P31997

Host Species:
Mouse

Purification Method:
Protein G Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human

Form:
Purified

Img

Sigma Aldrich

MABT326

clone 308/3-3, from mouse...


Antigen:
__

Classification:
__

Formulation:
__

Gene Symbols:
__

Immunogen:
__

Quantity:
__

Research Discipline:
__

Gene ID (Entrez):
__

Content And Storage:
__

Isotype:
__

Applications:
__

Clone:
__

Gene Accession No.:
__

Host Species:
__

Purification Method:
__

Regulatory Status:
__

Primary or Secondary:
__

Target Species:
__

Form:
__

Img

MilliporeSigma™

MABT326MI

--


Antigen:
CEACAM3/5

Classification:
Monoclonal

Formulation:
Purified mouse monoclonal IgG1κ in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.

Gene Symbols:
__

Immunogen:
Human IgG1 Fc-tagged recombinant human CEACAM3 extracellular domain.

Quantity:
100 μg

Research Discipline:
Cell Structure

Gene ID (Entrez):
NP_001806

Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.

Isotype:
IgG1 κ

Applications:
Flow Cytometry, Immunoprecipitation, Western Blot

Clone:
308/3-3

Gene Accession No.:
P40198

Host Species:
Mouse

Purification Method:
Protein G Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human

Form:
Purified