MAB3574C
MilliporeSigma™ Mouse anti-Vinculin (Ascites Free), Clone: VIIF9 (7F9),
Manufacturer: MilliporeSigma™
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | MAB3574C-Each-of-1 | In Stock | ₹ 39,063.27 |
MAB3574C - Each of 1
In Stock
Quantity
1
Base Price: ₹ 39,063.27
GST (18%): ₹ 7,031.389
Total Price: ₹ 46,094.659
Antigen
Vinculin (Ascites Free)
Classification
Monoclonal
Formulation
Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols
VCL; MVCL; CMD1W; CMH15
Immunogen
Human uterus meta-vinculin.
Quantity
100 μg
Research Discipline
Cell Structure
Gene ID (Entrez)
NP_003364
Content And Storage
Stable for one year at 2°C to 8°C from date of receipt.
Isotype
IgG1 κ
Applications
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Clone
VIIF9 (7F9)
Gene Accession No.
P18206
Host Species
Mouse
Purification Method
Protein G Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Target Species
Human, Mouse, Rabbit, Rat
Form
Purified
Related Products
Description
- Specifically detects Vinculin (Ascites Free) clone: VIIF9 (7F9) in Human, Mouse, Rabbit, Rat samples, and it is validated for Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blotting Metavinculin (MV) and its a.a
- 916-983 truncated splice variant Vinculin (UniProt P18206) are cytoskeleton proteins encoded by the VCL (also known as MVCL, CMD1W, CMH15) gene (Gene ID 7414) in human
- The N-terminal globular head domain (a.a
- 2-835) of Vinculin/VM contains binding sites for talin and α-actinin as well as a tyrosine phosphorylation site, while their C-terminal Tail region (a.a
- 879-1134 of VM; a.a
- 879-1066 of Vinculin) contains binding sites for F-actin, paxillin, and lipids
- Vinculin is associated with focal adhesion and adherens junctions, which are complexes that nucleate actin filaments and crosslinkers between the external medium, plasma membrane, and actin cytoskeleton
- The loss of vinculin disrupts focal adhesion complex formation and prevents cell adhesion and spreading, accompanied by reduced stress fiber formation and inhibition of lamellipodia extension
- Smooth muscles and skeletal muscles in their well-differentiated, contractile state co-express vinculin and meta-vinculin
- Both vinculin isoforms co-localize in muscular adhesive structures, such as dense plaques in smooth muscles, intercalated discs in cardiomyocytes, and costameres in skeletal muscles.
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Antigen: Vinculin (Ascites Free)
Classification: Monoclonal
Formulation: Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols: VCL; MVCL; CMD1W; CMH15
Immunogen: Human uterus meta-vinculin.
Quantity: 100 μg
Research Discipline: Cell Structure
Gene ID (Entrez): NP_003364
Content And Storage: Stable for one year at 2°C to 8°C from date of receipt.
Isotype: IgG1 κ
Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Clone: VIIF9 (7F9)
Gene Accession No.: P18206
Host Species: Mouse
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human, Mouse, Rabbit, Rat
Form: Purified
Antigen:
Vinculin (Ascites Free)
Classification:
Monoclonal
Formulation:
Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols:
VCL; MVCL; CMD1W; CMH15
Immunogen:
Human uterus meta-vinculin.
Quantity:
100 μg
Research Discipline:
Cell Structure
Gene ID (Entrez):
NP_003364
Content And Storage:
Stable for one year at 2°C to 8°C from date of receipt.
Isotype:
IgG1 κ
Applications:
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Clone:
VIIF9 (7F9)
Gene Accession No.:
P18206
Host Species:
Mouse
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rabbit, Rat
Form:
Purified
Antigen: Vinculin
Classification: Monoclonal
Formulation: Liquid in 0.02M Phosphate buffer with 0.25M NaCl and 0.1% sodium azide.
Gene Symbols: VCL, MVCL, Vinculin, Metavinculin, OTTHUMP00000043885, CMD1W, vinculin
Immunogen: Crude smooth muscle extract from normal human adult uterus.
Quantity: 100 μg
Research Discipline: __
Gene ID (Entrez): __
Content And Storage: 2-8°C in undiluted aliquots for up to 6 months.
Isotype: IgG1
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone: VIIF9 (7F9)
Gene Accession No.: NM_003373.3; NM_014000.2
Host Species: Mouse
Purification Method: __
Regulatory Status: __
Primary or Secondary: Primary
Target Species: Bovine, Human, Monkey, Mouse, Porcine, Rabbit
Form: Purified
Antigen:
Vinculin
Classification:
Monoclonal
Formulation:
Liquid in 0.02M Phosphate buffer with 0.25M NaCl and 0.1% sodium azide.
Gene Symbols:
VCL, MVCL, Vinculin, Metavinculin, OTTHUMP00000043885, CMD1W, vinculin
Immunogen:
Crude smooth muscle extract from normal human adult uterus.
Quantity:
100 μg
Research Discipline:
__
Gene ID (Entrez):
__
Content And Storage:
2-8°C in undiluted aliquots for up to 6 months.
Isotype:
IgG1
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone:
VIIF9 (7F9)
Gene Accession No.:
NM_003373.3; NM_014000.2
Host Species:
Mouse
Purification Method:
__
Regulatory Status:
__
Primary or Secondary:
Primary
Target Species:
Bovine, Human, Monkey, Mouse, Porcine, Rabbit
Form:
Purified
Antigen: Fyn
Classification: Monoclonal
Formulation: Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 μm filtered solution in PBS. with No Preservative
Gene Symbols: FYN
Immunogen: E. coli-derived recombinant human Fyn Met1-Gly83 Accession # P06241
Quantity: 25 μg
Research Discipline: __
Gene ID (Entrez): 2534
Content And Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.12 months from date of receipt, -20 to -70 degreesC as supplied. 1 month, 2 to 8 degreesC under sterile conditions after reconstitution. 6 months, -20 to -70 degreesC under sterile conditions after reconstitution.
Isotype: IgG1
Applications: Western Blot, Immunocytochemistry
Clone: 361228
Gene Accession No.: P06241
Host Species: Mouse
Purification Method: Protein A or G purified from hybridoma culture supernatant
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Form: Purified
Antigen:
Fyn
Classification:
Monoclonal
Formulation:
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 μm filtered solution in PBS. with No Preservative
Gene Symbols:
FYN
Immunogen:
E. coli-derived recombinant human Fyn Met1-Gly83 Accession # P06241
Quantity:
25 μg
Research Discipline:
__
Gene ID (Entrez):
2534
Content And Storage:
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.12 months from date of receipt, -20 to -70 degreesC as supplied. 1 month, 2 to 8 degreesC under sterile conditions after reconstitution. 6 months, -20 to -70 degreesC under sterile conditions after reconstitution.
Isotype:
IgG1
Applications:
Western Blot, Immunocytochemistry
Clone:
361228
Gene Accession No.:
P06241
Host Species:
Mouse
Purification Method:
Protein A or G purified from hybridoma culture supernatant
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Form:
Purified
Antigen: MKP-3/DUSP6
Classification: Monoclonal
Formulation: Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 μm filtered solution in PBS. with No Preservative
Gene Symbols: DUSP6
Immunogen: E. coli-derived recombinant human MKP-3 Ile2-Thr381 Accession # Q16828
Quantity: 100 μg
Research Discipline: __
Gene ID (Entrez): 1848
Content And Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.12 months from date of receipt, -20 to -70 degreesC as supplied. 1 month, 2 to 8 degreesC under sterile conditions after reconstitution. 6 months, -20 to -70 degreesC under sterile conditions after reconstitution.
Isotype: IgG2a
Applications: Western Blot
Clone: 363246
Gene Accession No.: Q16828
Host Species: Mouse
Purification Method: Protein A or G purified from hybridoma culture supernatant
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Form: Purified
Antigen:
MKP-3/DUSP6
Classification:
Monoclonal
Formulation:
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 μm filtered solution in PBS. with No Preservative
Gene Symbols:
DUSP6
Immunogen:
E. coli-derived recombinant human MKP-3 Ile2-Thr381 Accession # Q16828
Quantity:
100 μg
Research Discipline:
__
Gene ID (Entrez):
1848
Content And Storage:
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.12 months from date of receipt, -20 to -70 degreesC as supplied. 1 month, 2 to 8 degreesC under sterile conditions after reconstitution. 6 months, -20 to -70 degreesC under sterile conditions after reconstitution.
Isotype:
IgG2a
Applications:
Western Blot
Clone:
363246
Gene Accession No.:
Q16828
Host Species:
Mouse
Purification Method:
Protein A or G purified from hybridoma culture supernatant
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Form:
Purified