MABT326MI
MilliporeSigma™ CEACAM3/5, Mouse, Unlabeled, Clone: 308/3-3,
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | MABT326MI-Each-of-1 | In Stock | ₹ 38,734.72 |
MABT326MI - Each of 1
In Stock
Quantity
1
Base Price: ₹ 38,734.72
GST (18%): ₹ 6,972.25
Total Price: ₹ 45,706.97
Antigen
CEACAM3/5
Classification
Monoclonal
Concentration
Please refer to lot specific datasheet.
Formulation
Purified mouse monoclonal IgG1κ in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.
P40198
Immunogen
Human IgG1 Fc-tagged recombinant human CEACAM3 extracellular domain.
Quantity
100 μg
Research Discipline
Cell Structure
Gene ID (Entrez)
NP_001806
Target Species
Human
Form
Purified
Applications
Flow Cytometry, Immunoprecipitation, Western Blot
Clone
308/3-3
Conjugate
Unconjugated
Gene
CEACAM3, CD66D, CGM1, CEACAM5, CEA
Host Species
Mouse
Purification Method
Protein G Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Test Specificity
Clone 308/3-3 reacts with human CEACAM3 and CEACAM5, but not human CEACAM1/4/6/7/8, rat CEACAM1, or mouse CEACAM1 & CEACAM2.
Content And Storage
Stable for 1 year at 2°-8°C from date of receipt.
Isotype
IgG1 κ
Related Products
Description
- Carcinoembryonic antigen-related cell adhesion molecule 3 (UniProt P40198; also known as Carcinoembryonic antigen CGM1, CD66d) is encoded by the CEACAM3 (also known as CD66D, CGM1) gene (Gene ID 1084) in human
- The carcinoembryonic antigen- (CEA-) related cell adhesion molecules (CEACAMs) constitute a 12-member subgroup of the CEA family of immunoglobulin-related proteins first described in 1965 (PMID 4953873)
- CEACAMs are reported to participate in diverse physiological processes, including cell adhesion, differentiation, proliferation, and survival, as well as in carcinogenesis and bacterial pathogenesis
- CEACAM molecules from neighbouring cells can interact via their respective extracellular N-terminal IgV-like domain and mediate cell-to-cell adhesion through trans-oligomerization
- CEACAM molecules within the same cell can also undergo transmembrane domain-mediated cis-oligomerization, an event important for sustaining downstream cellular signaling
- Athough CEACAM1 is shown to utilize its cytoplasmic domain for transducing cellular signaling, not all CEACAM members are expressed with a significant cytoplasmic domain, and others (CEACAM5/6/7/8) are GPI-anchored without even a transmembrane domain
- Human CEACAM3 and CEACAM4 are two CEACAMs whose extracellular region is composed of only one V-type Ig-like extracellular domain (a.a
- 35-142 of CEACAM3)
- Human CEACAM5 (UniProt P06731), on the other hand, is a GPI-anchored CEACAM with the most extracellular Ig domains, 7 in all.
Compare Similar Items
Show Difference
Antigen: CEACAM3/5
Classification: Monoclonal
Concentration: Please refer to lot specific datasheet.
Formulation: Purified mouse monoclonal IgG1κ in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.: P40198
Immunogen: Human IgG1 Fc-tagged recombinant human CEACAM3 extracellular domain.
Quantity: 100 μg
Research Discipline: Cell Structure
Gene ID (Entrez): NP_001806
Target Species: Human
Form: Purified
Applications: Flow Cytometry, Immunoprecipitation, Western Blot
Clone: 308/3-3
Conjugate: Unconjugated
Gene: CEACAM3, CD66D, CGM1, CEACAM5, CEA
Host Species: Mouse
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Clone 308/3-3 reacts with human CEACAM3 and CEACAM5, but not human CEACAM1/4/6/7/8, rat CEACAM1, or mouse CEACAM1 & CEACAM2.
Content And Storage: Stable for 1 year at 2°-8°C from date of receipt.
Isotype: IgG1 κ
Antigen:
CEACAM3/5
Classification:
Monoclonal
Concentration:
Please refer to lot specific datasheet.
Formulation:
Purified mouse monoclonal IgG1κ in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.:
P40198
Immunogen:
Human IgG1 Fc-tagged recombinant human CEACAM3 extracellular domain.
Quantity:
100 μg
Research Discipline:
Cell Structure
Gene ID (Entrez):
NP_001806
Target Species:
Human
Form:
Purified
Applications:
Flow Cytometry, Immunoprecipitation, Western Blot
Clone:
308/3-3
Conjugate:
Unconjugated
Gene:
CEACAM3, CD66D, CGM1, CEACAM5, CEA
Host Species:
Mouse
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Clone 308/3-3 reacts with human CEACAM3 and CEACAM5, but not human CEACAM1/4/6/7/8, rat CEACAM1, or mouse CEACAM1 & CEACAM2.
Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.
Isotype:
IgG1 κ
Antigen: DDR1 (CD167a)
Classification: Monoclonal
Concentration: __
Formulation: Purified mouse monoclonal IgMκ in buffer containing PBS with 0.05% sodium azide.
Gene Accession No.: Q08345
Immunogen: Whole cells corresponding to human DDR1 (CD167a).
Quantity: 200 μL
Research Discipline: Cell Structure
Gene ID (Entrez): NP_001189450
Target Species: Human
Form: Purified
Applications: Functional Assay, Flow Cytometry
Clone: 48B3
Conjugate: __
Gene: __
Host Species: Mouse
Purification Method: Purified by Ion-Exchange Chromatography
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: __
Content And Storage: Stable for one year at 2°C to 8°C from date of receipt.
Isotype: IgM κ
Antigen:
DDR1 (CD167a)
Classification:
Monoclonal
Concentration:
__
Formulation:
Purified mouse monoclonal IgMκ in buffer containing PBS with 0.05% sodium azide.
Gene Accession No.:
Q08345
Immunogen:
Whole cells corresponding to human DDR1 (CD167a).
Quantity:
200 μL
Research Discipline:
Cell Structure
Gene ID (Entrez):
NP_001189450
Target Species:
Human
Form:
Purified
Applications:
Functional Assay, Flow Cytometry
Clone:
48B3
Conjugate:
__
Gene:
__
Host Species:
Mouse
Purification Method:
Purified by Ion-Exchange Chromatography
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
__
Content And Storage:
Stable for one year at 2°C to 8°C from date of receipt.
Isotype:
IgM κ
Antigen: Siglec-1 (CD169)
Classification: Monoclonal
Concentration: __
Formulation: Purified mouse monoclonal IgG2aκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Accession No.: Q9BZZ2
Immunogen: GST-tagged recombinant human Siglec-1 (CD169) N-terminal fragment containing the Ig-like V-type domain.
Quantity: 100 μg
Research Discipline: Cell Structure
Gene ID (Entrez): NP_075556
Target Species: Human, Mouse
Form: Purified
Applications: Immunohistochemistry (Paraffin), Western Blot
Clone: 5F1.1
Conjugate: Unconjugated
Gene: __
Host Species: Mouse
Purification Method: Protein G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Expected to react with all three spliced isoforms of human Siglec-1 (CD169)/Sialoadhesin reported by UniProt (Q9BZZ2).
Content And Storage: 2°C to 8°C for one year from date of shipment
Isotype: IgG2a κ
Antigen:
Siglec-1 (CD169)
Classification:
Monoclonal
Concentration:
__
Formulation:
Purified mouse monoclonal IgG2aκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Accession No.:
Q9BZZ2
Immunogen:
GST-tagged recombinant human Siglec-1 (CD169) N-terminal fragment containing the Ig-like V-type domain.
Quantity:
100 μg
Research Discipline:
Cell Structure
Gene ID (Entrez):
NP_075556
Target Species:
Human, Mouse
Form:
Purified
Applications:
Immunohistochemistry (Paraffin), Western Blot
Clone:
5F1.1
Conjugate:
Unconjugated
Gene:
__
Host Species:
Mouse
Purification Method:
Protein G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Expected to react with all three spliced isoforms of human Siglec-1 (CD169)/Sialoadhesin reported by UniProt (Q9BZZ2).
Content And Storage:
2°C to 8°C for one year from date of shipment
Isotype:
IgG2a κ
Antigen: __
Classification: __
Concentration: __
Formulation: __
Gene Accession No.: __
Immunogen: __
Quantity: __
Research Discipline: __
Gene ID (Entrez): __
Target Species: __
Form: __
Applications: __
Clone: __
Conjugate: __
Gene: __
Host Species: __
Purification Method: __
Regulatory Status: __
Primary or Secondary: __
Test Specificity: __
Content And Storage: __
Isotype: __
Antigen:
__
Classification:
__
Concentration:
__
Formulation:
__
Gene Accession No.:
__
Immunogen:
__
Quantity:
__
Research Discipline:
__
Gene ID (Entrez):
__
Target Species:
__
Form:
__
Applications:
__
Clone:
__
Conjugate:
__
Gene:
__
Host Species:
__
Purification Method:
__
Regulatory Status:
__
Primary or Secondary:
__
Test Specificity:
__
Content And Storage:
__
Isotype:
__