MABF299MI

MilliporeSigma™ CCR2, Mouse, Unlabeled, Clone: 8C3.1,

Manufacturer: MilliporeSigma™

Select a Size

Pack Size SKU Availability Price
Each of 1 MABF299MI-Each-of-1 In Stock ₹ 41,307.51

MABF299MI - Each of 1

₹ 41,307.51

In Stock

Quantity

1

Base Price: ₹ 41,307.51

GST (18%): ₹ 7,435.352

Total Price: ₹ 48,742.862

Antigen

CCR2

Classification

Monoclonal

Concentration

Please refer to lot specific datasheet.

Formulation

Purified mouse monoclonal antibody IgG2a in buffer containing 0.1M Tris-Glycine (pH 7.4) 150mM NaCl with 0.05% Sodium Azide.

Gene Accession No.

P41597

Immunogen

GST-tagged recombinant human N-terminal extracellular domain.

Quantity

100 μL

Research Discipline

Inflammation & Immunology

Gene ID (Entrez)

NP_001116513

Target Species

Human

Form

Purified

Applications

Western Blot

Clone

8C3.1

Conjugate

Unconjugated

Gene

CCR2, CMKBR2

Host Species

Mouse

Purification Method

Protein G Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Test Specificity

Clone 8C3.1 targets the N-terminal extracelluar domain of human CCR2 spliced isoforms 1&2 reported by Uniprot (P41597).

Content And Storage

Stable for 1 year at 2°-8°C from date of receipt.

Isotype

IgG2a κ

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Description

  • C-C chemokine receptor type 2 (UniProt P41597; also known as C-C CKR-2, CC-CKR-2, CCR-2, CCR2, CD192, MCP-1-R, Monocyte chemoattractant protein 1 receptor) is encoded by the CCR2 (also known as CMKBR2) gene (Gene ID 729230) in human
  • CC chemokine receptors (CCRs) are 7-transmembrane G protein-coupled receptors (GPCRs) that bind CC chemokines (CCLs) and mediate their biological activities
  • CCRs and CCLs play a central role in physiological and pathological recruitment of immune cells
  • CCR2 can interact with CCL2, CCL8 and CCL16, it is found on the surface of monocytes, activated memory T cells, B cells, and basophils in humans, and also in peritoneal macrophages in mice
  • CCR2 plays an important role in the recruitment of monocytes/macrophages and T cells
  • CCR2-knockout mice show a partial defect in macrophage function, decreased Th1 immune response, reduced delayed-type hypersensitivity reaction, and are more susceptible to pathogenic bacteria infections
  • Human CCR2 is a 7-transmembrane (a.a
  • 43-70, 81-100, 115-136, 154-178, 207-226, 244-268, 286-309) GPCR with an N-terminal extracellular domain (a.a
  • 1-42) and a C-terminoal cytoplasmic domain (a.a
  • 310-374).

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MilliporeSigma™

MABF299MI

--


Antigen:
CCR2

Classification:
Monoclonal

Concentration:
Please refer to lot specific datasheet.

Formulation:
Purified mouse monoclonal antibody IgG2a in buffer containing 0.1M Tris-Glycine (pH 7.4) 150mM NaCl with 0.05% Sodium Azide.

Gene Accession No.:
P41597

Immunogen:
GST-tagged recombinant human N-terminal extracellular domain.

Quantity:
100 μL

Research Discipline:
Inflammation & Immunology

Gene ID (Entrez):
NP_001116513

Target Species:
Human

Form:
Purified

Applications:
Western Blot

Clone:
8C3.1

Conjugate:
Unconjugated

Gene:
CCR2, CMKBR2

Host Species:
Mouse

Purification Method:
Protein G Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Test Specificity:
Clone 8C3.1 targets the N-terminal extracelluar domain of human CCR2 spliced isoforms 1&2 reported by Uniprot (P41597).

Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.

Isotype:
IgG2a κ

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MilliporeSigma

MABF301MI

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Antigen:
Interleukin-7/IL-7

Classification:
Monoclonal

Concentration:
__

Formulation:
Purified mouse monoclonal IgG2aκ in buffer containing 0.1MTris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.

Gene Accession No.:
NP_000871

Immunogen:
GST-tagged recombinant protein corresponding to human Interleukin-7/IL-7.

Quantity:
100 μg

Research Discipline:
__

Gene ID (Entrez):
__

Target Species:
Human

Form:
Purified

Applications:
Flow Cytometry, Western Blot

Clone:
7B1.1

Conjugate:
Unconjugated

Gene:
__

Host Species:
Mouse

Purification Method:
Protein G purified

Regulatory Status:
__

Primary or Secondary:
Primary

Test Specificity:
__

Content And Storage:
2-8°C for one year

Isotype:
IgG2a κ

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Target Species:
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Concentration:
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Gene Accession No.:
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Research Discipline:
__

Gene ID (Entrez):
__

Target Species:
__

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Gene:
__

Host Species:
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Purification Method:
__

Regulatory Status:
__

Primary or Secondary:
__

Test Specificity:
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Isotype:
__