MABC613MI
MilliporeSigma™ Mouse anti-B7-H6, Clone: 5.51.18,
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | MABC613MI-Each-of-1 | In Stock | ₹ 42,677.33 |
MABC613MI - Each of 1
In Stock
Quantity
1
Base Price: ₹ 42,677.33
GST (18%): ₹ 7,681.919
Total Price: ₹ 50,359.249
Antigen
B7-H6
Classification
Monoclonal
Formulation
Purified mouse monoclonal IgG1κ in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols
NCR3LG1; B7H6
Immunogen
Recombinant protein corresponding to the extracellular domain of human B7-H6.
Quantity
100 μg
Research Discipline
Apoptosis, Cancer
Gene ID (Entrez)
NP_001189368
Content And Storage
Stable for one year at 2°C to 8°C from date of receipt.
Isotype
IgG1 κ
Applications
Flow Cytometry
Clone
5.51.18
Gene Accession No.
Q68D85
Host Species
Mouse
Purification Method
Protein G Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Target Species
Human
Form
Purified
Related Products
Description
- Specifically detects B7-H6 clone: 5.51.18 in Human samples, and it is validated for Flow Cytometry B7-H6 (also known as B7 homolog 6 or Natural cytotoxicity triggering receptor 3 ligand 1) is a single-pass membrane protein encoded by the NCR3LG1 or B7H6 gene (Entrez Gene ID 374383) in human
- B7-H6 belongs to the B7 family of structurally related cell-surface ligands, which bind to receptors on lymphocytes that regulate immune responses
- The natural cytotoxicity receptor NCR3/NKp30 is involved in NK-cell–mediated killing of various tumor cell lines
- B7-H6 is identified as the NKp30 ligand on cancer cells, while normal tissues were reported to lack B7-H6 transcripts
- Decreased NKp30 expression is reported to correlate with poor prognosis and survival among patients with acute myeloid leukemia (AML)
- Class I histone deacetylases HDAC2 & HDAC3 are reported to be involved in B7-H6 transcription activation, and HDAC inhibitors are found to impair tumor cell recognition by NK cells
- This monoclonal antibody is suitable for flow cytometric analysis, but does not compete against NKp30 binding (PMID 23801635).
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Antigen: B7-H6
Classification: Monoclonal
Formulation: Purified mouse monoclonal IgG1κ in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols: NCR3LG1; B7H6
Immunogen: Recombinant protein corresponding to the extracellular domain of human B7-H6.
Quantity: 100 μg
Research Discipline: Apoptosis, Cancer
Gene ID (Entrez): NP_001189368
Content And Storage: Stable for one year at 2°C to 8°C from date of receipt.
Isotype: IgG1 κ
Applications: Flow Cytometry
Clone: 5.51.18
Gene Accession No.: Q68D85
Host Species: Mouse
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human
Form: Purified
Antigen:
B7-H6
Classification:
Monoclonal
Formulation:
Purified mouse monoclonal IgG1κ in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols:
NCR3LG1; B7H6
Immunogen:
Recombinant protein corresponding to the extracellular domain of human B7-H6.
Quantity:
100 μg
Research Discipline:
Apoptosis, Cancer
Gene ID (Entrez):
NP_001189368
Content And Storage:
Stable for one year at 2°C to 8°C from date of receipt.
Isotype:
IgG1 κ
Applications:
Flow Cytometry
Clone:
5.51.18
Gene Accession No.:
Q68D85
Host Species:
Mouse
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Human
Form:
Purified
Antigen: NOX4
Classification: Monoclonal
Formulation: Mouse monoclonal IgG2bκ hybridoma culture supernatant without preservatives.
Gene Symbols: __
Immunogen: GST-tagged recombinant protein corresponding to a fragment from the third extracellular loop of human NOX4.
Quantity: 100 μL
Research Discipline: Apoptosis & Cancer
Gene ID (Entrez): NP_001137308
Content And Storage: Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Isotype: IgG2b κ
Applications: Western Blot
Clone: 10A8.1
Gene Accession No.: Q9NPH5
Host Species: Mouse
Purification Method: Unpurified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human
Form: Culture Supernatant
Antigen:
NOX4
Classification:
Monoclonal
Formulation:
Mouse monoclonal IgG2bκ hybridoma culture supernatant without preservatives.
Gene Symbols:
__
Immunogen:
GST-tagged recombinant protein corresponding to a fragment from the third extracellular loop of human NOX4.
Quantity:
100 μL
Research Discipline:
Apoptosis & Cancer
Gene ID (Entrez):
NP_001137308
Content And Storage:
Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Isotype:
IgG2b κ
Applications:
Western Blot
Clone:
10A8.1
Gene Accession No.:
Q9NPH5
Host Species:
Mouse
Purification Method:
Unpurified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Human
Form:
Culture Supernatant
Antigen: KLF4
Classification: Monoclonal
Formulation: Mouse monoclonal IgG1 ascitic fluid containing up to 0.1% sodium azide.
Gene Symbols: EZF, GKLF, KLF4
Immunogen: Purified recombinant fragment of human KLF4 expressed in E. coli.
Quantity: 100 μL
Research Discipline: __
Gene ID (Entrez): __
Content And Storage: −20°C in undiluted aliquots for up to 12 months. Avoid repeated freeze/thaw cycles.
Isotype: IgG1
Applications: Immunohistochemistry, Western Blot
Clone: 1E06
Gene Accession No.: NP_004226
Host Species: Mouse
Purification Method: Unpurified
Regulatory Status: __
Primary or Secondary: Primary
Target Species: Human
Form: Ascites
Antigen:
KLF4
Classification:
Monoclonal
Formulation:
Mouse monoclonal IgG1 ascitic fluid containing up to 0.1% sodium azide.
Gene Symbols:
EZF, GKLF, KLF4
Immunogen:
Purified recombinant fragment of human KLF4 expressed in E. coli.
Quantity:
100 μL
Research Discipline:
__
Gene ID (Entrez):
__
Content And Storage:
−20°C in undiluted aliquots for up to 12 months. Avoid repeated freeze/thaw cycles.
Isotype:
IgG1
Applications:
Immunohistochemistry, Western Blot
Clone:
1E06
Gene Accession No.:
NP_004226
Host Species:
Mouse
Purification Method:
Unpurified
Regulatory Status:
__
Primary or Secondary:
Primary
Target Species:
Human
Form:
Ascites
Antigen: MUM1
Classification: Monoclonal
Formulation: Mouse monoclonal IgG1 ascitic fluid containing up to 0.1% sodium azide.
Gene Symbols: MUM-1, EXPAND1, MUM1
Immunogen: Purified recombinant fragment of human MUM1 expressed in E. Coli.
Quantity: 100 μL
Research Discipline: __
Gene ID (Entrez): __
Content And Storage: −20°C in undiluted aliquots for up to 12 months. Avoid repeated freeze/thaw cycles.
Isotype: IgG1
Applications: Immunohistochemistry, Western Blot
Clone: 4G10
Gene Accession No.: __
Host Species: Mouse
Purification Method: Unpurified
Regulatory Status: __
Primary or Secondary: Primary
Target Species: Human
Form: Ascites
Antigen:
MUM1
Classification:
Monoclonal
Formulation:
Mouse monoclonal IgG1 ascitic fluid containing up to 0.1% sodium azide.
Gene Symbols:
MUM-1, EXPAND1, MUM1
Immunogen:
Purified recombinant fragment of human MUM1 expressed in E. Coli.
Quantity:
100 μL
Research Discipline:
__
Gene ID (Entrez):
__
Content And Storage:
−20°C in undiluted aliquots for up to 12 months. Avoid repeated freeze/thaw cycles.
Isotype:
IgG1
Applications:
Immunohistochemistry, Western Blot
Clone:
4G10
Gene Accession No.:
__
Host Species:
Mouse
Purification Method:
Unpurified
Regulatory Status:
__
Primary or Secondary:
Primary
Target Species:
Human
Form:
Ascites