MABC966MI

MilliporeSigma™ Mouse anti-Perforin-1, Clone: dG9,

Manufacturer: MilliporeSigma™

Select a Size

Pack Size SKU Availability Price
Each of 1 MABC966MI-Each-of-1 In Stock ₹ 41,307.51

MABC966MI - Each of 1

₹ 41,307.51

In Stock

Quantity

1

Base Price: ₹ 41,307.51

GST (18%): ₹ 7,435.352

Total Price: ₹ 48,742.862

Antigen

Perforin-1

Classification

Monoclonal

Formulation

Purified mouse monoclonal IgG2bκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.

Gene Symbols

PRF1; PFP

Immunogen

Purified granules from the human cytotoxic large granular lymphocytes lymphoma line YT corresponding to human Perforin-1.

Quantity

100 μg

Research Discipline

Apoptosis, Cancer

Gene ID (Entrez)

NP_001076585

Content And Storage

Stable for one year at 2°C to 8°C from date of receipt.

Isotype

IgG2b κ

Applications

Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Immunoprecipitation

Clone

dG9

Gene Accession No.

P14222

Host Species

Mouse

Purification Method

Protein G Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Target Species

Human

Form

Purified

Related Products

Img

MilliporeSigma™

MABC553MI

--

Img

MilliporeSigma™

MABF913

--

Img

MilliporeSigma™

MABC663MI

--

Img

MilliporeSigma™

MABT323MI

--

Img

MilliporeSigma™

MABC269MI

--

Img

MilliporeSigma™

MABC550MI

--

Img

MilliporeSigma™

MABE1094

--

Img

MilliporeSigma™

MABS1252

--

Description

  • Specifically detects Perforin-1 clone: dG9 in Human samples, and it is validated for Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Immunoprecipitation Perforin-1 (UniProt P14222; also known as Cytolysin, Lymphocyte pore forming protein, P1, PFP) is encoded by the PRF1 (Also known as FLH2, HPLH2, PFN1, PFP) gene in human (Gene ID 5551)
  • Perforin is a secreted protein synthesized by activated cytotoxic T lymphocytes (CTL) and natural killer (NK) cells
  • It is a key component of the secreted lytic granule of CTL and NK cells
  • Perforin inserts into the phospholipid bilayer of the target cell plasma membrane, and polymerises to form a pore of ∼16 nm that causes target cell death by osmotic lysis and by allowing other lytic granule components, most notably granzyme B, to enter the targeted cells
  • Perforin is synthesized as a 70kDa inactive precursor which is cleaved at the C-terminus to yield a 60kDa active form.

Compare Similar Items

Show Difference

Img

MilliporeSigma™

MABC966MI

--


Antigen:
Perforin-1

Classification:
Monoclonal

Formulation:
Purified mouse monoclonal IgG2bκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.

Gene Symbols:
PRF1; PFP

Immunogen:
Purified granules from the human cytotoxic large granular lymphocytes lymphoma line YT corresponding to human Perforin-1.

Quantity:
100 μg

Research Discipline:
Apoptosis, Cancer

Gene ID (Entrez):
NP_001076585

Content And Storage:
Stable for one year at 2°C to 8°C from date of receipt.

Isotype:
IgG2b κ

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Immunoprecipitation

Clone:
dG9

Gene Accession No.:
P14222

Host Species:
Mouse

Purification Method:
Protein G Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human

Form:
Purified

Img

MilliporeSigma

MABC967MI

--


Antigen:
Kallikrein 7/KLK7

Classification:
Monoclonal

Formulation:
__

Gene Symbols:
KLK7,PRSS6,SCCE

Immunogen:
A full length recombinant human pro-Kallikrein 7.

Quantity:
100 μg

Research Discipline:
Apoptosis and Cancer

Gene ID (Entrez):
NP_005037.1

Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.

Isotype:
IgG1 κ

Applications:
ELISA, Immunohistochemistry (Paraffin)

Clone:
73-1

Gene Accession No.:
__

Host Species:
Mouse

Purification Method:
__

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human

Form:
Purified

Img

MilliporeSigma™

MABC974MI

--


Antigen:
Dysferlin/DYSF

Classification:
Monoclonal

Formulation:
Purified mouse monoclonal IgG2bκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.

Gene Symbols:
DYSF; FER1L1

Immunogen:
GST-tagged recombinant protein corresponding to the N-terminal of human Dysferlin/DYSF.

Quantity:
100 μg

Research Discipline:
Apoptosis, Cancer

Gene ID (Entrez):
NP_003485

Content And Storage:
Stable for one year at 2°C to 8°C from date of receipt.

Isotype:
IgG2b κ

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
10H3.1

Gene Accession No.:
O75923

Host Species:
Mouse

Purification Method:
Protein G Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human

Form:
Purified

Img

MilliporeSigma

MABC97MI

--


Antigen:
S1PR4/EDG6

Classification:
Monoclonal

Formulation:
Purified mouse monoclonal IgMκ in buffer containing PBS with 0.05% sodium azide.

Gene Symbols:
S1PR4, EDG6

Immunogen:
GST-tagged recombinant protein corresponding to human S1PR4/EDG6.

Quantity:
100 μg

Research Discipline:
__

Gene ID (Entrez):
__

Content And Storage:
2-8°C for one year

Isotype:
IgM κ

Applications:
Immunohistochemistry, Western Blot

Clone:
16B9.1

Gene Accession No.:
NP_003766

Host Species:
Mouse

Purification Method:
Purified by ion-exchange chromatography

Regulatory Status:
__

Primary or Secondary:
Primary

Target Species:
Human, Rat

Form:
Purified