MABF911MI
MilliporeSigma™ Aminopeptidase N/CD13, Mouse, Unlabeled, Clone: BR2,
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | MABF911MI-Each-of-1 | In Stock | ₹ 41,307.51 |
MABF911MI - Each of 1
In Stock
Quantity
1
Base Price: ₹ 41,307.51
GST (18%): ₹ 7,435.352
Total Price: ₹ 48,742.862
Antigen
Aminopeptidase N/CD13
Classification
Monoclonal
Concentration
Please refer to lot specific datasheet.
Formulation
Purified mouse monoclonal IgG1κ in buffer containing 0.1M Tris-Glycine (pH 7.4) 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.
P15144
Immunogen
Human foreskin fibroblasts.
Quantity
100 μg
Research Discipline
Apoptosis & Cancer
Gene ID (Entrez)
NP_001141.2
Target Species
Human
Form
Purified
Applications
Immunoassay, ELISA, Flow Cytometry, Immunoprecipitation
Clone
BR2
Conjugate
Unconjugated
Gene
ANPEP, APN, CD13, PEPN
Host Species
Mouse
Purification Method
Protein G Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Test Specificity
Clone BR2 targets aminopeptidase N/CD13 extracellular domain without inhibiting its enzymatic activity (Piela-Smith, T.H., and Korn, J.H. (1995). Cell Immunol. 1995 Apr 15 162(1):42-48). Clone BR2 specifically stains human foreskin fibroblasts, but not HUVECs, human intestinal SMCs, human keratinocytes (RHEK-1), human squamous cell carcinoma lines A-431 and NCI-H292, nor does it cross-react with rat or murine fibroblasts (Chen, L.L., et al. (1993). J. Tissue Cult. Methods.15:1-10).
Content And Storage
Stable for 1 year at 2°-8°C from date of receipt.
Isotype
IgG1 κ
Related Products
Description
- Aminopeptidase N (EC 3.4.11.2; UniProt P15144; also known as Alanyl aminopeptidase, Aminopeptidase M, AP-M, AP-N, CD13, gp150, hAPN, Microsomal aminopeptidase, Myeloid plasma membrane glycoprotein CD13) is encoded by the ANPEP (also known as APN, CD13, PEPN) gene (Gene ID 290) in human
- Aminopeptidase N (CD13) is a 150kDa membrane glycoprotein belonging to the superfamily of zinc metalloproteases
- CD13 preferentially cleaves N-terminus neutral amino acids, most notably alanine residue, and is widely expressed as a homodimer of 280 kDa on the cell surface in many tissues, including intestinal epithelia and the nervous system
- CD13 is involved in many physiological processes such as antigen presention regulation, differentiation, proliferation, apoptosis, chemotaxis, phagocytosis, pain sensation, adhesion, viral infection, cancer metastasis and angiogenesis
- CD13 mediates its biological functions through its role as a receptor or co-receptor in cellular signaling, as well as via peptidase activity
- CD13 is a receptor for human coronavirus (HCoV) and cytomegalovirus (HCMV), and many proteins are found in complex with CD13, including galectin-3, galectin-4, Grb2, IgG receptors (Fc Rs), reversion-inducing cysteine-rich protein with kazal motifs, Sos, and the pro-inflammatory cytokine 14-3-3
- Human CD13 consists of a short N-terminal cytoplasmic end (a.a
- 2-8), a transmembrane domain (a.a
- 9-32), and a large extracellular portion (a.a
- 33-967) composed of a Ser/Thr-rich region (a.a
- 33-68) and the metalloprotease domain (a.a
- 69-967), including an HCoV-229E-interacting region (a.a
- 26-353) and a Substrate-binding region (a.a
- 352-356).
Compare Similar Items
Show Difference
Antigen: Aminopeptidase N/CD13
Classification: Monoclonal
Concentration: Please refer to lot specific datasheet.
Formulation: Purified mouse monoclonal IgG1κ in buffer containing 0.1M Tris-Glycine (pH 7.4) 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.: P15144
Immunogen: Human foreskin fibroblasts.
Quantity: 100 μg
Research Discipline: Apoptosis & Cancer
Gene ID (Entrez): NP_001141.2
Target Species: Human
Form: Purified
Applications: Immunoassay, ELISA, Flow Cytometry, Immunoprecipitation
Clone: BR2
Conjugate: Unconjugated
Gene: ANPEP, APN, CD13, PEPN
Host Species: Mouse
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Clone BR2 targets aminopeptidase N/CD13 extracellular domain without inhibiting its enzymatic activity (Piela-Smith, T.H., and Korn, J.H. (1995). Cell Immunol. 1995 Apr 15 162(1):42-48). Clone BR2 specifically stains human foreskin fibroblasts, but not HUVECs, human intestinal SMCs, human keratinocytes (RHEK-1), human squamous cell carcinoma lines A-431 and NCI-H292, nor does it cross-react with rat or murine fibroblasts (Chen, L.L., et al. (1993). J. Tissue Cult. Methods.15:1-10).
Content And Storage: Stable for 1 year at 2°-8°C from date of receipt.
Isotype: IgG1 κ
Antigen:
Aminopeptidase N/CD13
Classification:
Monoclonal
Concentration:
Please refer to lot specific datasheet.
Formulation:
Purified mouse monoclonal IgG1κ in buffer containing 0.1M Tris-Glycine (pH 7.4) 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.:
P15144
Immunogen:
Human foreskin fibroblasts.
Quantity:
100 μg
Research Discipline:
Apoptosis & Cancer
Gene ID (Entrez):
NP_001141.2
Target Species:
Human
Form:
Purified
Applications:
Immunoassay, ELISA, Flow Cytometry, Immunoprecipitation
Clone:
BR2
Conjugate:
Unconjugated
Gene:
ANPEP, APN, CD13, PEPN
Host Species:
Mouse
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Clone BR2 targets aminopeptidase N/CD13 extracellular domain without inhibiting its enzymatic activity (Piela-Smith, T.H., and Korn, J.H. (1995). Cell Immunol. 1995 Apr 15 162(1):42-48). Clone BR2 specifically stains human foreskin fibroblasts, but not HUVECs, human intestinal SMCs, human keratinocytes (RHEK-1), human squamous cell carcinoma lines A-431 and NCI-H292, nor does it cross-react with rat or murine fibroblasts (Chen, L.L., et al. (1993). J. Tissue Cult. Methods.15:1-10).
Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.
Isotype:
IgG1 κ
Antigen: CD37
Classification: Monoclonal
Concentration: __
Formulation: Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Accession No.: P11049
Immunogen: Lymph node cells from a lymphoma patient.
Quantity: 100 μg
Research Discipline: Inflammation and Immunology
Gene ID (Entrez): NP_001765.1
Target Species: Human
Form: Purified
Applications: Flow Cytometry, Immunohistochemistry, Immunoprecipitation
Clone: MB-1
Conjugate: __
Gene: __
Host Species: Mouse
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: __
Content And Storage: Stable for one year at 2°C to 8°C from date of receipt.
Isotype: IgG1 κ
Antigen:
CD37
Classification:
Monoclonal
Concentration:
__
Formulation:
Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Accession No.:
P11049
Immunogen:
Lymph node cells from a lymphoma patient.
Quantity:
100 μg
Research Discipline:
Inflammation and Immunology
Gene ID (Entrez):
NP_001765.1
Target Species:
Human
Form:
Purified
Applications:
Flow Cytometry, Immunohistochemistry, Immunoprecipitation
Clone:
MB-1
Conjugate:
__
Gene:
__
Host Species:
Mouse
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
__
Content And Storage:
Stable for one year at 2°C to 8°C from date of receipt.
Isotype:
IgG1 κ
Antigen: __
Classification: __
Concentration: __
Formulation: __
Gene Accession No.: __
Immunogen: __
Quantity: __
Research Discipline: __
Gene ID (Entrez): __
Target Species: __
Form: __
Applications: __
Clone: __
Conjugate: __
Gene: __
Host Species: __
Purification Method: __
Regulatory Status: __
Primary or Secondary: __
Test Specificity: __
Content And Storage: __
Isotype: __
Antigen:
__
Classification:
__
Concentration:
__
Formulation:
__
Gene Accession No.:
__
Immunogen:
__
Quantity:
__
Research Discipline:
__
Gene ID (Entrez):
__
Target Species:
__
Form:
__
Applications:
__
Clone:
__
Conjugate:
__
Gene:
__
Host Species:
__
Purification Method:
__
Regulatory Status:
__
Primary or Secondary:
__
Test Specificity:
__
Content And Storage:
__
Isotype:
__
Antigen: CRACC
Classification: Monoclonal
Concentration: Please refer to lot specific datasheet.
Formulation: Purified rat monoclonal IgG1κ antibody in PBS without preservatives.
Gene Accession No.: Q8BHK6
Immunogen: Human IgG1 Fc -tagged recombinant mouse CRACC extracellular domain.
Quantity: 100 μg
Research Discipline: Inflammation & Immunology
Gene ID (Entrez): NP_653122.2
Target Species: Mouse
Form: Purified
Applications: Functional Assay, Immunoprecipitation
Clone: 4G2
Conjugate: Unconjugated
Gene: Slamf7, Cs1
Host Species: Rat
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Clone 4G2 reacted with murine T lymphoma BI-141 transfectants expressing mouse CRACC but not with those transfected with other members of the SLAM family (CD84, 2B4, Ly9, Ly108 or SLAM) (Cruz-Munoz, M.E., et al. (2009). Nat. Immunol. 10(3):297-305). Expected to react with all four spliced isoforms of murine CRACC reported by UniProt (Q8BHK6).
Content And Storage: Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Isotype: IgG1 κ
Antigen:
CRACC
Classification:
Monoclonal
Concentration:
Please refer to lot specific datasheet.
Formulation:
Purified rat monoclonal IgG1κ antibody in PBS without preservatives.
Gene Accession No.:
Q8BHK6
Immunogen:
Human IgG1 Fc -tagged recombinant mouse CRACC extracellular domain.
Quantity:
100 μg
Research Discipline:
Inflammation & Immunology
Gene ID (Entrez):
NP_653122.2
Target Species:
Mouse
Form:
Purified
Applications:
Functional Assay, Immunoprecipitation
Clone:
4G2
Conjugate:
Unconjugated
Gene:
Slamf7, Cs1
Host Species:
Rat
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Clone 4G2 reacted with murine T lymphoma BI-141 transfectants expressing mouse CRACC but not with those transfected with other members of the SLAM family (CD84, 2B4, Ly9, Ly108 or SLAM) (Cruz-Munoz, M.E., et al. (2009). Nat. Immunol. 10(3):297-305). Expected to react with all four spliced isoforms of murine CRACC reported by UniProt (Q8BHK6).
Content And Storage:
Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Isotype:
IgG1 κ