MABF986MI
MilliporeSigma™ Eosinophil Cationic Protein, Mouse, Unlabeled, Clone: 1C8.5/D8,
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | MABF986MI-Each-of-1 | In Stock | ₹ 38,734.72 |
MABF986MI - Each of 1
In Stock
Quantity
1
Base Price: ₹ 38,734.72
GST (18%): ₹ 6,972.25
Total Price: ₹ 45,706.97
Antigen
Eosinophil Cationic Protein
Classification
Monoclonal
Concentration
Please refer to lot specific datasheet.
Formulation
Purified mouse monoclonal IgG1 antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.
P12724
Immunogen
Purified human ECP.
Quantity
100 μg
Research Discipline
Inflammation & Immunology
Gene ID (Entrez)
NP_002926
Target Species
Human
Form
Purified
Applications
Immunohistochemistry (Paraffin), Immunoassay, Western Blot
Clone
1C8.5/D8
Conjugate
Unconjugated
Gene
RNASE3, ECP, RNS3
Host Species
Mouse
Purification Method
Protein G Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Test Specificity
Clone 1C8.5/D9 specifically reacted with ECP, but not other granule proteins by Western blotting analysis (Makiya, M.A., et al. (2014). J. Immunol. Methods. 411:11-22).
Content And Storage
Stable for 1 year at 2°-8°C from date of receipt.
Isotype
IgG1
Related Products
Description
- Eosinophil cationic protein (UniProt P12724; also known as ECP, Ribonuclease 3, RNase 3) is encoded by the RNASE3 (also known as ECP, RNS3) gene (Gene ID 6037) in human
- The major basic protein (MBP), eosinophil cationic protein (ECP), eosinophil derived neurotoxin (EDN) and eosinophil peroxidase (EPO), are eosinophil effector molecules implicated in host defense, immunoregulatory responses, and in allergic and inflammatory reactions
- These highly cationic proteins are stored preformed within the eosinophil secondary granules and released in intact membrane-bound granules during cell lysis or through a complex system of vesiculotubular structures during “piecemeal necrosis”
- While eosinophil count and eosinophil surface expression of the activation marker CD69 are significantly correlated with serum concentrations of MBP, EDN and EPO, studies show that they are not correlated with ECP level
- On the other hand, eosinophilic disease patients with normal eosinophil count show significantly increased concentrations of MBP, ECP, EDN, and EPO compared to normal donors
- The measurement of MBP, ECP, EDN, and EPO levels thus provides a better predictor than eosinophil count alone in disease diagnosis
- ECP is produced with a signal peptide sequence (a.a
- 1-27), the removal of which yields the mature (a.a
- 28-160) protein.
Compare Similar Items
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Antigen: Eosinophil Cationic Protein
Classification: Monoclonal
Concentration: Please refer to lot specific datasheet.
Formulation: Purified mouse monoclonal IgG1 antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.: P12724
Immunogen: Purified human ECP.
Quantity: 100 μg
Research Discipline: Inflammation & Immunology
Gene ID (Entrez): NP_002926
Target Species: Human
Form: Purified
Applications: Immunohistochemistry (Paraffin), Immunoassay, Western Blot
Clone: 1C8.5/D8
Conjugate: Unconjugated
Gene: RNASE3, ECP, RNS3
Host Species: Mouse
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Clone 1C8.5/D9 specifically reacted with ECP, but not other granule proteins by Western blotting analysis (Makiya, M.A., et al. (2014). J. Immunol. Methods. 411:11-22).
Content And Storage: Stable for 1 year at 2°-8°C from date of receipt.
Isotype: IgG1
Antigen:
Eosinophil Cationic Protein
Classification:
Monoclonal
Concentration:
Please refer to lot specific datasheet.
Formulation:
Purified mouse monoclonal IgG1 antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.:
P12724
Immunogen:
Purified human ECP.
Quantity:
100 μg
Research Discipline:
Inflammation & Immunology
Gene ID (Entrez):
NP_002926
Target Species:
Human
Form:
Purified
Applications:
Immunohistochemistry (Paraffin), Immunoassay, Western Blot
Clone:
1C8.5/D8
Conjugate:
Unconjugated
Gene:
RNASE3, ECP, RNS3
Host Species:
Mouse
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Clone 1C8.5/D9 specifically reacted with ECP, but not other granule proteins by Western blotting analysis (Makiya, M.A., et al. (2014). J. Immunol. Methods. 411:11-22).
Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.
Isotype:
IgG1
Antigen: Amyloid β
Classification: Monoclonal
Concentration: __
Formulation: Purified mouse monoclonal IgG2aκ in buffer containing 0.1MTris-Glycine (pH 7.4, 150mM NaCl) with 0.05% sodium azide.
Gene Accession No.: NP_000475
Immunogen: Human Amyloid β peptide
Quantity: 50 μg
Research Discipline: __
Gene ID (Entrez): __
Target Species: Human, Mouse
Form: Purified
Applications: ELISA, Immunohistochemistry, Western Blot
Clone: WO2
Conjugate: Unconjugated
Gene: __
Host Species: Mouse
Purification Method: Protein G purfied
Regulatory Status: __
Primary or Secondary: Primary
Test Specificity: __
Content And Storage: 2-8°C for one year
Isotype: IgG2a κ
Antigen:
Amyloid β
Classification:
Monoclonal
Concentration:
__
Formulation:
Purified mouse monoclonal IgG2aκ in buffer containing 0.1MTris-Glycine (pH 7.4, 150mM NaCl) with 0.05% sodium azide.
Gene Accession No.:
NP_000475
Immunogen:
Human Amyloid β peptide
Quantity:
50 μg
Research Discipline:
__
Gene ID (Entrez):
__
Target Species:
Human, Mouse
Form:
Purified
Applications:
ELISA, Immunohistochemistry, Western Blot
Clone:
WO2
Conjugate:
Unconjugated
Gene:
__
Host Species:
Mouse
Purification Method:
Protein G purfied
Regulatory Status:
__
Primary or Secondary:
Primary
Test Specificity:
__
Content And Storage:
2-8°C for one year
Isotype:
IgG2a κ
Antigen: SRY
Classification: Monoclonal
Concentration: __
Formulation: Purified mouse monoclonal in PBS containing up to 0.1% sodium azide and 0.5% protein stabilizer.
Gene Accession No.: __
Immunogen: Purified recombinant fragment of human SRY expressed in E. Coli
Quantity: 100 μL
Research Discipline: __
Gene ID (Entrez): __
Target Species: Human
Form: Purified
Applications: ELISA, Flow Cytometry, Immunohistochemistry, Western Blot
Clone: 1G4
Conjugate: Unconjugated
Gene: __
Host Species: Mouse
Purification Method: Protein G purified
Regulatory Status: __
Primary or Secondary: Primary
Test Specificity: __
Content And Storage: 2-8°C for one year
Isotype: IgG1
Antigen:
SRY
Classification:
Monoclonal
Concentration:
__
Formulation:
Purified mouse monoclonal in PBS containing up to 0.1% sodium azide and 0.5% protein stabilizer.
Gene Accession No.:
__
Immunogen:
Purified recombinant fragment of human SRY expressed in E. Coli
Quantity:
100 μL
Research Discipline:
__
Gene ID (Entrez):
__
Target Species:
Human
Form:
Purified
Applications:
ELISA, Flow Cytometry, Immunohistochemistry, Western Blot
Clone:
1G4
Conjugate:
Unconjugated
Gene:
__
Host Species:
Mouse
Purification Method:
Protein G purified
Regulatory Status:
__
Primary or Secondary:
Primary
Test Specificity:
__
Content And Storage:
2-8°C for one year
Isotype:
IgG1
Antigen: Glutamine Synthetase
Classification: Monoclonal
Concentration: Please refer to lot specific datasheet.
Formulation: Purified mouse monoclonal IgG2aκ in buffer containing 0.1M Tris-Glycine (pH 7.4) 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.: P09606
Immunogen: GST-tagged recombinant rat glutamine synthetase internal fragment.
Quantity: 100 μL
Research Discipline: Neuroscience
Gene ID (Entrez): NP_058769
Target Species: Human
Form: Purified
Applications: Western Blot
Clone: 11A3.1
Conjugate: Unconjugated
Gene: Glul, Glns
Host Species: Mouse
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Clone 11A3.1 targets an internal epitope within the C-terminal half of human and rat glutamine synthetase.
Content And Storage: Stable for 1 year at 2°-8°C from date of receipt.
Isotype: IgG2a κ
Antigen:
Glutamine Synthetase
Classification:
Monoclonal
Concentration:
Please refer to lot specific datasheet.
Formulation:
Purified mouse monoclonal IgG2aκ in buffer containing 0.1M Tris-Glycine (pH 7.4) 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.:
P09606
Immunogen:
GST-tagged recombinant rat glutamine synthetase internal fragment.
Quantity:
100 μL
Research Discipline:
Neuroscience
Gene ID (Entrez):
NP_058769
Target Species:
Human
Form:
Purified
Applications:
Western Blot
Clone:
11A3.1
Conjugate:
Unconjugated
Gene:
Glul, Glns
Host Species:
Mouse
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Clone 11A3.1 targets an internal epitope within the C-terminal half of human and rat glutamine synthetase.
Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.
Isotype:
IgG2a κ