MABT1240MI
MilliporeSigma™ Cathepsin G, Mouse, Unlabeled, Clone: AHN-11,
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | MABT1240MI-Each-of-1 | In Stock | ₹ 41,307.51 |
MABT1240MI - Each of 1
In Stock
Quantity
1
Base Price: ₹ 41,307.51
GST (18%): ₹ 7,435.352
Total Price: ₹ 48,742.862
Antigen
Cathepsin G
Classification
Monoclonal
Concentration
Please refer to lot specific datasheet.
Formulation
Purified mouse monoclonal IgG2aκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.
P08311
Immunogen
Human neutrophils.
Quantity
100 μg
Research Discipline
Cell Structure
Gene ID (Entrez)
NP_001902
Target Species
Human
Form
Purified
Applications
Immunocytochemistry, Radioimmune Assays (RIA), Western Blot
Clone
AHN-11
Conjugate
Unconjugated
Gene
CTSG
Host Species
Mouse
Purification Method
Protein G Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Test Specificity
Clone AHN-11 reacted specifically with neutrophil cathepsin G, but not the homologous neutrophil neutral proteases, elastase, proteinase 3, or esterase N (Skubitz, K.M., et al. (1989). J. Leukoc. Biol. 46(2):109-118).
Content And Storage
Stable for 1 year at 2°-8°C from date of receipt.
Isotype
IgG2a κ
Related Products
Description
- Cathepsin G (EC 3.4.21.20; UniProt P08311; also known as CatG, CG) is encoded by the CTSG gene (Gene ID 1511) in human
- Cathepsin G is a peptidase S1 protein family protease found in azurophil granules of neutrophilic polymorphonuclear leukocytes
- Cathepsin G displays a substrate specificity similar to that of chymotrypsin C, but it is most closely related to other immune serine proteases, such as neutrophil elastase and the granzymes
- Cathepsin G is involved in connective tissue remodeling at sites of inflammation
- Cathepsin G is also a component of neutrophil extracellular traps (NETs) composed of ejected lattice of chromatin enmeshed with granular and nuclear proteins, including histones, calprotectin and cathepsin G, that are capable of capturing and killing microbial invaders
- Antibodies raised against cathepsin G or histones have been shown to limit the bactericidal capacity of NETs towards pathogens
- Cathepsin G is prouduced with a signal peptide (a.a
- 1-18) and a propeptide sequence (a.a
- 19-20) that are removed posttranslationally to yield the mature (a.a
- 21-255) enzyme.
Compare Similar Items
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Antigen: Cathepsin G
Classification: Monoclonal
Concentration: Please refer to lot specific datasheet.
Formulation: Purified mouse monoclonal IgG2aκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.: P08311
Immunogen: Human neutrophils.
Quantity: 100 μg
Research Discipline: Cell Structure
Gene ID (Entrez): NP_001902
Target Species: Human
Form: Purified
Applications: Immunocytochemistry, Radioimmune Assays (RIA), Western Blot
Clone: AHN-11
Conjugate: Unconjugated
Gene: CTSG
Host Species: Mouse
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Clone AHN-11 reacted specifically with neutrophil cathepsin G, but not the homologous neutrophil neutral proteases, elastase, proteinase 3, or esterase N (Skubitz, K.M., et al. (1989). J. Leukoc. Biol. 46(2):109-118).
Content And Storage: Stable for 1 year at 2°-8°C from date of receipt.
Isotype: IgG2a κ
Antigen:
Cathepsin G
Classification:
Monoclonal
Concentration:
Please refer to lot specific datasheet.
Formulation:
Purified mouse monoclonal IgG2aκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.:
P08311
Immunogen:
Human neutrophils.
Quantity:
100 μg
Research Discipline:
Cell Structure
Gene ID (Entrez):
NP_001902
Target Species:
Human
Form:
Purified
Applications:
Immunocytochemistry, Radioimmune Assays (RIA), Western Blot
Clone:
AHN-11
Conjugate:
Unconjugated
Gene:
CTSG
Host Species:
Mouse
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Clone AHN-11 reacted specifically with neutrophil cathepsin G, but not the homologous neutrophil neutral proteases, elastase, proteinase 3, or esterase N (Skubitz, K.M., et al. (1989). J. Leukoc. Biol. 46(2):109-118).
Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.
Isotype:
IgG2a κ
Antigen: __
Classification: __
Concentration: __
Formulation: __
Gene Accession No.: __
Immunogen: __
Quantity: __
Research Discipline: __
Gene ID (Entrez): __
Target Species: __
Form: __
Applications: __
Clone: __
Conjugate: __
Gene: __
Host Species: __
Purification Method: __
Regulatory Status: __
Primary or Secondary: __
Test Specificity: __
Content And Storage: __
Isotype: __
Antigen:
__
Classification:
__
Concentration:
__
Formulation:
__
Gene Accession No.:
__
Immunogen:
__
Quantity:
__
Research Discipline:
__
Gene ID (Entrez):
__
Target Species:
__
Form:
__
Applications:
__
Clone:
__
Conjugate:
__
Gene:
__
Host Species:
__
Purification Method:
__
Regulatory Status:
__
Primary or Secondary:
__
Test Specificity:
__
Content And Storage:
__
Isotype:
__
Antigen: Heparan Sulfate Proteoglycan (Perlecan)
Classification: Monoclonal
Concentration: __
Formulation: Purified mouse monoclonal IgG1κ in buffer containing 0.1MTris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Accession No.: NP_005520
Immunogen: Full length recombinant protein corresponding to human Perlecan.
Quantity: 100 μg
Research Discipline: __
Gene ID (Entrez): __
Target Species: Human
Form: Purified
Applications: Immunohistochemistry
Clone: 5D7-2E4
Conjugate: Unconjugated
Gene: __
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: __
Primary or Secondary: Primary
Test Specificity: __
Content And Storage: 2-8°C for one year
Isotype: IgG1 κ
Antigen:
Heparan Sulfate Proteoglycan (Perlecan)
Classification:
Monoclonal
Concentration:
__
Formulation:
Purified mouse monoclonal IgG1κ in buffer containing 0.1MTris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Accession No.:
NP_005520
Immunogen:
Full length recombinant protein corresponding to human Perlecan.
Quantity:
100 μg
Research Discipline:
__
Gene ID (Entrez):
__
Target Species:
Human
Form:
Purified
Applications:
Immunohistochemistry
Clone:
5D7-2E4
Conjugate:
Unconjugated
Gene:
__
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
__
Primary or Secondary:
Primary
Test Specificity:
__
Content And Storage:
2-8°C for one year
Isotype:
IgG1 κ
Antigen: BCL-6
Classification: Monoclonal
Concentration: __
Formulation: __
Gene Accession No.: NP_001697
Immunogen: pCDNA3‐BCL6 plasmid vector (full length sequence of human BCL-6).
Quantity: 100 μg
Research Discipline: Apoptosis and Cancer
Gene ID (Entrez): __
Target Species: Mouse, Human, Rat
Form: Purified
Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot
Clone: GI191E/A8
Conjugate: Unconjugated
Gene: __
Host Species: Mouse
Purification Method: Protein G Purified
Regulatory Status: __
Primary or Secondary: Primary
Test Specificity: Clone GI191E/A8 specifically detects BCL-6 in Human, Mouse, and Rat tissues.
Content And Storage: Stable for 1 year at 2 to 8°C from date of receipt.
Isotype: IgG1 κ
Antigen:
BCL-6
Classification:
Monoclonal
Concentration:
__
Formulation:
__
Gene Accession No.:
NP_001697
Immunogen:
pCDNA3‐BCL6 plasmid vector (full length sequence of human BCL-6).
Quantity:
100 μg
Research Discipline:
Apoptosis and Cancer
Gene ID (Entrez):
__
Target Species:
Mouse, Human, Rat
Form:
Purified
Applications:
ELISA, Immunohistochemistry (Paraffin), Western Blot
Clone:
GI191E/A8
Conjugate:
Unconjugated
Gene:
__
Host Species:
Mouse
Purification Method:
Protein G Purified
Regulatory Status:
__
Primary or Secondary:
Primary
Test Specificity:
Clone GI191E/A8 specifically detects BCL-6 in Human, Mouse, and Rat tissues.
Content And Storage:
Stable for 1 year at 2 to 8°C from date of receipt.
Isotype:
IgG1 κ