MABC1170MI
MilliporeSigma™ MNDA, Rat, Unlabeled, Clone: 3C1,
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | MABC1170MI-Each-of-1 | In Stock | ₹ 37,453.03 |
MABC1170MI - Each of 1
In Stock
Quantity
1
Base Price: ₹ 37,453.03
GST (18%): ₹ 6,741.545
Total Price: ₹ 44,194.575
Antigen
MNDA
Classification
Monoclonal
Concentration
Please refer to lot specific datasheet.
Formulation
Purified rat monoclonal antibody IgG1 in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.
P41218
Immunogen
Human peripheral blood granulocyte nuclei.
Quantity
100 μg
Research Discipline
Apoptosis & Cancer
Gene ID (Entrez)
NP_002423
Target Species
Human
Form
Purified
Applications
Flow Cytometry, Immunocytochemistry, Immunoprecipitation, Western Blot
Clone
3C1
Conjugate
Unconjugated
Gene
MNDA
Host Species
Rat
Purification Method
Protein G Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Test Specificity
Clone 3C1 reacted with both denatured and non-denatured MNDA. Clone 3C1 reacted with nuclear extract from NMDA-expressing HL-60, but not non-MNDA-expressing BII, human myeloid leukemia cells (Hudson, C.R., et al. (1988). Hybridoma. 7(6):541-553).
Content And Storage
Stable for 1 year at 2°-8°C from date of receipt.
Isotype
IgG1 κ
Related Products
Description
- Myeloid cell nuclear differentiation antigen (UniProt P41218) is encoded by the MNDA gene (Gene ID 4332) in human
- MNDA is a member of the interferon-inducible p200 (IFI-200) family of proteins with a conserved HIN-200 domain (human MNDA a.a
- 196-394) that mediate interaction with proteins and DNA
- IFI-200 members possess antimicrobial, cell growth regulatory, differential regulatory and immunomodulatory properties
- In bone marrow-derived- and mature neutrophils, MNDA is predominantly located in the nucleus
- MNDA is cleaved by caspases in neutrophils undergoing apoptosis and relocated to the cytoplasm
- MNDA is downregulated in myelodysplastic syndrome and completely absent in a mouse strain susceptible to B-cell plasmacytoma, while being markedly (1,000-fold) upregulated in a mouse strain resistant to B-cell plasmacytoma
- Originally thought to be restricted to, myeloid cells, MNDA and other IFI-200 family members are also found to be expressed in a variety of non-myeloid cell types
- MNDA is highly expressed in normal bone tissue, while being at markedly low levels in osteosarcoma cells
- MNDA overexpression is shown to induce apoptosis, inhibit proliferation, and reduce the migration of osteosarcoma cells.
Compare Similar Items
Show Difference
Antigen: MNDA
Classification: Monoclonal
Concentration: Please refer to lot specific datasheet.
Formulation: Purified rat monoclonal antibody IgG1 in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.: P41218
Immunogen: Human peripheral blood granulocyte nuclei.
Quantity: 100 μg
Research Discipline: Apoptosis & Cancer
Gene ID (Entrez): NP_002423
Target Species: Human
Form: Purified
Applications: Flow Cytometry, Immunocytochemistry, Immunoprecipitation, Western Blot
Clone: 3C1
Conjugate: Unconjugated
Gene: MNDA
Host Species: Rat
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Clone 3C1 reacted with both denatured and non-denatured MNDA. Clone 3C1 reacted with nuclear extract from NMDA-expressing HL-60, but not non-MNDA-expressing BII, human myeloid leukemia cells (Hudson, C.R., et al. (1988). Hybridoma. 7(6):541-553).
Content And Storage: Stable for 1 year at 2°-8°C from date of receipt.
Isotype: IgG1 κ
Antigen:
MNDA
Classification:
Monoclonal
Concentration:
Please refer to lot specific datasheet.
Formulation:
Purified rat monoclonal antibody IgG1 in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.:
P41218
Immunogen:
Human peripheral blood granulocyte nuclei.
Quantity:
100 μg
Research Discipline:
Apoptosis & Cancer
Gene ID (Entrez):
NP_002423
Target Species:
Human
Form:
Purified
Applications:
Flow Cytometry, Immunocytochemistry, Immunoprecipitation, Western Blot
Clone:
3C1
Conjugate:
Unconjugated
Gene:
MNDA
Host Species:
Rat
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Clone 3C1 reacted with both denatured and non-denatured MNDA. Clone 3C1 reacted with nuclear extract from NMDA-expressing HL-60, but not non-MNDA-expressing BII, human myeloid leukemia cells (Hudson, C.R., et al. (1988). Hybridoma. 7(6):541-553).
Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.
Isotype:
IgG1 κ
Antigen: ALK
Classification: Monoclonal
Concentration: __
Formulation: Purified mouse monoclonal antibody IgG3 in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Gene Accession No.: __
Immunogen: His-tagged full length human recombinant ALK tyrosine kinase receptor.
Quantity: 100 μg
Research Discipline: Signaling
Gene ID (Entrez): NP_004295
Target Species: Human
Form: Purified
Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone: ALK1
Conjugate: Unconjugated
Gene: __
Host Species: Mouse
Purification Method: Protein G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Clone ALK1 specifically detects human ALK tyrosine kinase receptor. It targets an epitope with in 102 amino acids from the C-terminal region.
Content And Storage: Stable for 1 year at 2-8°C from date of receipt.
Isotype: IgG3 κ
Antigen:
ALK
Classification:
Monoclonal
Concentration:
__
Formulation:
Purified mouse monoclonal antibody IgG3 in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Gene Accession No.:
__
Immunogen:
His-tagged full length human recombinant ALK tyrosine kinase receptor.
Quantity:
100 μg
Research Discipline:
Signaling
Gene ID (Entrez):
NP_004295
Target Species:
Human
Form:
Purified
Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone:
ALK1
Conjugate:
Unconjugated
Gene:
__
Host Species:
Mouse
Purification Method:
Protein G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Clone ALK1 specifically detects human ALK tyrosine kinase receptor. It targets an epitope with in 102 amino acids from the C-terminal region.
Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.
Isotype:
IgG3 κ
Antigen: ALK
Classification: Monoclonal
Concentration: __
Formulation: Purified mouse monoclonal antibody IgG3 in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Gene Accession No.: __
Immunogen: His-tagged full length human recombinant ALK tyrosine kinase receptor.
Quantity: 25 μg
Research Discipline: Signaling
Gene ID (Entrez): NP_004295
Target Species: Human
Form: Purified
Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone: ALK1
Conjugate: Unconjugated
Gene: __
Host Species: Mouse
Purification Method: Protein G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Clone ALK1 specifically detects human ALK tyrosine kinase receptor. It targets an epitope with in 102 amino acids from the C-terminal region.
Content And Storage: Stable for 1 year at 2-8°C from date of receipt.
Isotype: IgG3 κ
Antigen:
ALK
Classification:
Monoclonal
Concentration:
__
Formulation:
Purified mouse monoclonal antibody IgG3 in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Gene Accession No.:
__
Immunogen:
His-tagged full length human recombinant ALK tyrosine kinase receptor.
Quantity:
25 μg
Research Discipline:
Signaling
Gene ID (Entrez):
NP_004295
Target Species:
Human
Form:
Purified
Applications:
Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Clone:
ALK1
Conjugate:
Unconjugated
Gene:
__
Host Species:
Mouse
Purification Method:
Protein G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Clone ALK1 specifically detects human ALK tyrosine kinase receptor. It targets an epitope with in 102 amino acids from the C-terminal region.
Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.
Isotype:
IgG3 κ
Antigen: Stat3b
Classification: Monoclonal
Concentration: Please refer to lot specific datasheet.
Formulation: Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.: P40763-3
Immunogen: Linear peptide containing human Stat3b C-terminal end 7 a.a. (CT7).
Quantity: 100 μg
Research Discipline: Apoptosis & Cancer
Gene ID (Entrez): NP_998827
Target Species: Human
Form: Purified
Applications: Western Blot
Clone: 516 G10H9
Conjugate: Unconjugated
Gene: STAT3, ADMIO, APRF, HIES
Host Species: Mouse
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Test Specificity: Clone 516 G10H9 detects the C-terminal end 7-a.a. (CT7) sequence present in human/mouse spliced isoform Stat3B (UniProt P40763-3/P42227-2), but not in human/mouse spliced isoform Stat3A (UniProt P40763-1/P42227-1) or human/mouse isoform Del-701 (UniProt P40763-2/P42227-3).
Content And Storage: Stable for 1 year at 2°-8°C from date of receipt.
Isotype: IgG1 κ
Antigen:
Stat3b
Classification:
Monoclonal
Concentration:
Please refer to lot specific datasheet.
Formulation:
Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% Sodium Azide.
Gene Accession No.:
P40763-3
Immunogen:
Linear peptide containing human Stat3b C-terminal end 7 a.a. (CT7).
Quantity:
100 μg
Research Discipline:
Apoptosis & Cancer
Gene ID (Entrez):
NP_998827
Target Species:
Human
Form:
Purified
Applications:
Western Blot
Clone:
516 G10H9
Conjugate:
Unconjugated
Gene:
STAT3, ADMIO, APRF, HIES
Host Species:
Mouse
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Test Specificity:
Clone 516 G10H9 detects the C-terminal end 7-a.a. (CT7) sequence present in human/mouse spliced isoform Stat3B (UniProt P40763-3/P42227-2), but not in human/mouse spliced isoform Stat3A (UniProt P40763-1/P42227-1) or human/mouse isoform Del-701 (UniProt P40763-2/P42227-3).
Content And Storage:
Stable for 1 year at 2°-8°C from date of receipt.
Isotype:
IgG1 κ