MABS1304MI
MilliporeSigma™ anti-ATP Synthase subunit beta Clone: 11/21-7-A8,
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | MABS1304MI-Each-of-1 | In Stock | ₹ 40,486.99 |
MABS1304MI - Each of 1
In Stock
Quantity
1
Base Price: ₹ 40,486.99
GST (18%): ₹ 7,287.658
Total Price: ₹ 47,774.648
Antigen
ATP Synthase subunit β
Classification
Monoclonal
Conjugate
Unconjugated
Gene Accession No.
P06576
Host Species
Mouse
Purification Method
Protein G purified
Regulatory Status
RUO
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Form
Purified
Applications
Dot Blot, ELISA, Immunocytochemistry, Western Blot
Clone
11/21-7-A8
Formulation
Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols
ATP5B, ATPMB, ATPSB
Immunogen
His-tagged recombinant protein corresponding to human ATP Synthase subunit β.
Quantity
100 μg
Research Discipline
Signaling
Gene ID (Entrez)
NP_001677
Content And Storage
2°C to 8°C for one year from date of shipment
Isotype
IgG1 κ
Related Products
Description
- Specifically detects ATP Synthase subunit β Clone: 11/21-7-A8 in Human, Mouse, Rat samples, and it is validated for Dot Blot, ELISA, Immunocytochemistry, Western Blotting ATP synthase subunit beta, mitochondrial (EC 3.6.3.14; UniProt P06576; also known as ATP synthase H+ transporting mitochondrial F1 complex beta polypeptide, beta-F1-ATPase, Epididymis secretory protein Li 271, Mitochondrial ATP synthase beta subunit, Mitochondrial ATP synthetase beta subunit) is encoded by the ATP5B (also known as ATPMB, ATPSB, HEL-S-271) gene (Gene ID 506) in human
- Mitochondrial ATP synthase produces ATP from ADP in the presence of a proton gradient generated by electron transport complexes
- This ATPase contains two structural domains, F1-containing extramembrane catalytic core, and F0-containing the membrane proton channel that are linked via a central stalk and a peripheral stalk
- Subunits alpha and beta form the catalytic code in F1
- Tumor development requires the selection of cancer cells with a repressed biogenesis and functional activity of mitochondria
- Both beta-F1-ATPase/GAPDH and beta-F1-ATPase/Hsp60 ratios are found to be significantly lower in tumors than the corresponding normal tissues
- Studies conducted in human colon cancer cell line HCT116 show the involvement of AMPK (AMP-activated protein kinase) and GCN2 (general control non-derepressible 2; eIF2α kinase) in the onset of colon cancer progression by repressing of beta-F1-ATPase synthesis and promoting the abnormal bioenergetics of mitochondria.
Compare Similar Items
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Antigen: ATP Synthase subunit β
Classification: Monoclonal
Conjugate: Unconjugated
Gene Accession No.: P06576
Host Species: Mouse
Purification Method: Protein G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Form: Purified
Applications: Dot Blot, ELISA, Immunocytochemistry, Western Blot
Clone: 11/21-7-A8
Formulation: Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols: ATP5B, ATPMB, ATPSB
Immunogen: His-tagged recombinant protein corresponding to human ATP Synthase subunit β.
Quantity: 100 μg
Research Discipline: Signaling
Gene ID (Entrez): NP_001677
Content And Storage: 2°C to 8°C for one year from date of shipment
Isotype: IgG1 κ
Antigen:
ATP Synthase subunit β
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene Accession No.:
P06576
Host Species:
Mouse
Purification Method:
Protein G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Form:
Purified
Applications:
Dot Blot, ELISA, Immunocytochemistry, Western Blot
Clone:
11/21-7-A8
Formulation:
Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols:
ATP5B, ATPMB, ATPSB
Immunogen:
His-tagged recombinant protein corresponding to human ATP Synthase subunit β.
Quantity:
100 μg
Research Discipline:
Signaling
Gene ID (Entrez):
NP_001677
Content And Storage:
2°C to 8°C for one year from date of shipment
Isotype:
IgG1 κ
Antigen: Apolipoprotein A-I
Classification: Monoclonal
Conjugate: Unconjugated
Gene Accession No.: __
Host Species: Mouse
Purification Method: Protein G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human
Form: Purified
Applications: Dot Blot, ELISA, Immunocytochemistry, Western Blot
Clone: Wt20-7
Formulation: Purified mouse monoclonal antibody IgG1 in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Gene Symbols: APOA1
Immunogen: GST-tagged full-length human recombinant Apolipoprotein A-I
Quantity: 100 μL
Research Discipline: Signaling
Gene ID (Entrez): NP_000030
Content And Storage: Stable for 1 year at 2-8°C from date of receipt.
Isotype: IgG1
Antigen:
Apolipoprotein A-I
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene Accession No.:
__
Host Species:
Mouse
Purification Method:
Protein G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Human
Form:
Purified
Applications:
Dot Blot, ELISA, Immunocytochemistry, Western Blot
Clone:
Wt20-7
Formulation:
Purified mouse monoclonal antibody IgG1 in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Gene Symbols:
APOA1
Immunogen:
GST-tagged full-length human recombinant Apolipoprotein A-I
Quantity:
100 μL
Research Discipline:
Signaling
Gene ID (Entrez):
NP_000030
Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.
Isotype:
IgG1
Antigen: Apolipoprotein A-I
Classification: Monoclonal
Conjugate: Unconjugated
Gene Accession No.: __
Host Species: Mouse
Purification Method: Protein G purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human
Form: Purified
Applications: Dot Blot, ELISA, Immunocytochemistry, Western Blot
Clone: Wt20-7
Formulation: Purified mouse monoclonal antibody IgG1 in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Gene Symbols: APOA1
Immunogen: GST-tagged full-length human recombinant Apolipoprotein A-I
Quantity: 25 μL
Research Discipline: Signaling
Gene ID (Entrez): NP_000030
Content And Storage: Stable for 1 year at 2-8°C from date of receipt.
Isotype: IgG1
Antigen:
Apolipoprotein A-I
Classification:
Monoclonal
Conjugate:
Unconjugated
Gene Accession No.:
__
Host Species:
Mouse
Purification Method:
Protein G purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Human
Form:
Purified
Applications:
Dot Blot, ELISA, Immunocytochemistry, Western Blot
Clone:
Wt20-7
Formulation:
Purified mouse monoclonal antibody IgG1 in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Gene Symbols:
APOA1
Immunogen:
GST-tagged full-length human recombinant Apolipoprotein A-I
Quantity:
25 μL
Research Discipline:
Signaling
Gene ID (Entrez):
NP_000030
Content And Storage:
Stable for 1 year at 2-8°C from date of receipt.
Isotype:
IgG1
Antigen: __
Classification: __
Conjugate: __
Gene Accession No.: __
Host Species: __
Purification Method: __
Regulatory Status: __
Primary or Secondary: __
Target Species: __
Form: __
Applications: __
Clone: __
Formulation: __
Gene Symbols: __
Immunogen: __
Quantity: __
Research Discipline: __
Gene ID (Entrez): __
Content And Storage: __
Isotype: __
Antigen:
__
Classification:
__
Conjugate:
__
Gene Accession No.:
__
Host Species:
__
Purification Method:
__
Regulatory Status:
__
Primary or Secondary:
__
Target Species:
__
Form:
__
Applications:
__
Clone:
__
Formulation:
__
Gene Symbols:
__
Immunogen:
__
Quantity:
__
Research Discipline:
__
Gene ID (Entrez):
__
Content And Storage:
__
Isotype:
__