MABN790MI
MilliporeSigma™ Mouse anti-Shank3, Clone: 16E2.3,
Manufacturer: MilliporeSigma™
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | MABN790MI-Each-of-1 | In Stock | ₹ 38,734.72 |
MABN790MI - Each of 1
In Stock
Quantity
1
Base Price: ₹ 38,734.72
GST (18%): ₹ 6,972.25
Total Price: ₹ 45,706.97
Antigen
Shank3
Classification
Monoclonal
Formulation
Purified mouse monoclonal IgG2aκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols
SHANK3; KIAA1650; PROSAP2; PSAP2
Immunogen
GST-tagged recombinant protein corresponding to the C-terminal half of human Shank3.
Quantity
100 μg
Research Discipline
Neuroscience
Gene ID (Entrez)
NP_277052
Content And Storage
Stable for one year at 2°C to 8°C from date of receipt.
Isotype
IgG2a κ
Applications
Western Blot
Clone
16E2.3
Gene Accession No.
Q9BYB0
Host Species
Mouse
Purification Method
Protein G Purified
Regulatory Status
RUO
Primary or Secondary
Primary
Target Species
Mouse
Form
Purified
Related Products
Description
- Specifically detects Shank3 clone: 16E2.3 in Mouse samples, and it is validated for Western Blotting SH3 and multiple ankyrin repeat domains protein 3 (UniProt Q9BYB0; also known as Proline rich synapse associated protein 2, ProSAP2, Shank postsynaptic density protein, Shank3) is encoded by the SHANK3 (also known as DEL22q13.3, PROSAP2, PSAP2, SCZD15, SPANK-2) gene (Gene ID 85358) in human
- Shank3/ProSAP2 belongs to the ProSAP/Shank family of scaffolding proteins, which are important dendritic spines postsynaptic density (PSD) complex components that play an important role in linking membrane glutamate receptors to intracellular signaling proteins and actin cytoskeleton
- Shank proteins interact with adaptor proteins and assembles glutamate receptors at the postsynaptic membrane via multiple domains, including ankyrin repeat, proline-rich, SH3, PSD95/disc-large/zona occludens-1 (PDZ), and SAM domains
- Shanks, together with the adaptor protein Homer and the endocytic vesicle-associated protein dynamin-3, are required for proper localization of the endocytic zone in close proximity to the PSD
- Shank-3 induces formation of functional dendritic spines in aspiny cerebellar neurons, whereas Shank-3 knockdown results in reduced spine density and size in cultured hippocampal neurons
- SHANK3 gene mutations are known causes of mental retardation and autism spectrum disorders.
Compare Similar Items
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Antigen: Shank3
Classification: Monoclonal
Formulation: Purified mouse monoclonal IgG2aκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols: SHANK3; KIAA1650; PROSAP2; PSAP2
Immunogen: GST-tagged recombinant protein corresponding to the C-terminal half of human Shank3.
Quantity: 100 μg
Research Discipline: Neuroscience
Gene ID (Entrez): NP_277052
Content And Storage: Stable for one year at 2°C to 8°C from date of receipt.
Isotype: IgG2a κ
Applications: Western Blot
Clone: 16E2.3
Gene Accession No.: Q9BYB0
Host Species: Mouse
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Mouse
Form: Purified
Antigen:
Shank3
Classification:
Monoclonal
Formulation:
Purified mouse monoclonal IgG2aκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols:
SHANK3; KIAA1650; PROSAP2; PSAP2
Immunogen:
GST-tagged recombinant protein corresponding to the C-terminal half of human Shank3.
Quantity:
100 μg
Research Discipline:
Neuroscience
Gene ID (Entrez):
NP_277052
Content And Storage:
Stable for one year at 2°C to 8°C from date of receipt.
Isotype:
IgG2a κ
Applications:
Western Blot
Clone:
16E2.3
Gene Accession No.:
Q9BYB0
Host Species:
Mouse
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Mouse
Form:
Purified
Antigen: GLAST
Classification: Monoclonal
Formulation: Purified mouse monoclonal IgG1λ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols: SLC1A3; EAAT1; GLAST; GLAST1
Immunogen: GST-tagged recombinant protein corresponding to the extracellular domain of human GLAST.
Quantity: 100 μg
Research Discipline: Neuroscience
Gene ID (Entrez): NP_004163
Content And Storage: Stable for one year at 2°C to 8°C from date of receipt.
Isotype: IgG1 λ
Applications: Immunohistochemistry, Western Blot
Clone: 8C11.1
Gene Accession No.: P43003
Host Species: Mouse
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human, Rat
Form: Purified
Antigen:
GLAST
Classification:
Monoclonal
Formulation:
Purified mouse monoclonal IgG1λ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols:
SLC1A3; EAAT1; GLAST; GLAST1
Immunogen:
GST-tagged recombinant protein corresponding to the extracellular domain of human GLAST.
Quantity:
100 μg
Research Discipline:
Neuroscience
Gene ID (Entrez):
NP_004163
Content And Storage:
Stable for one year at 2°C to 8°C from date of receipt.
Isotype:
IgG1 λ
Applications:
Immunohistochemistry, Western Blot
Clone:
8C11.1
Gene Accession No.:
P43003
Host Species:
Mouse
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Human, Rat
Form:
Purified
Antigen: Ribeye
Classification: Monoclonal
Formulation: Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols: CTBP2
Immunogen: GST-tagged recombinant protein corresponding to the N-terminal region of human Ribeye.
Quantity: 100 μg
Research Discipline: Neuroscience
Gene ID (Entrez): NP_073713
Content And Storage: Stable for one year at 2°C to 8°C from date of receipt.
Isotype: IgG1 κ
Applications: Immunohistochemistry (Paraffin), Western Blot
Clone: 3D12.1
Gene Accession No.: P56545-2
Host Species: Mouse
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human
Form: Purified
Antigen:
Ribeye
Classification:
Monoclonal
Formulation:
Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols:
CTBP2
Immunogen:
GST-tagged recombinant protein corresponding to the N-terminal region of human Ribeye.
Quantity:
100 μg
Research Discipline:
Neuroscience
Gene ID (Entrez):
NP_073713
Content And Storage:
Stable for one year at 2°C to 8°C from date of receipt.
Isotype:
IgG1 κ
Applications:
Immunohistochemistry (Paraffin), Western Blot
Clone:
3D12.1
Gene Accession No.:
P56545-2
Host Species:
Mouse
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Human
Form:
Purified
Antigen: EYS
Classification: Monoclonal
Formulation: Purified mouse monoclonal IgG2bκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols: EYS; C6orf178; C6orf179; C6orf180; EGFL10; EGFL11; SPAM; UNQ9424/PRO34591
Immunogen: GST-tagged recombinant human EYS fragment corresponding to the EGF-like domains 9-11.
Quantity: 100 μg
Research Discipline: Neuroscience
Gene ID (Entrez): NP_001136272
Content And Storage: Stable for one year at 2°C to 8°C from date of receipt.
Isotype: IgG2b κ
Applications: Immunohistochemistry (Paraffin), Western Blot
Clone: 3G10.1
Gene Accession No.: Q5T1H1
Host Species: Mouse
Purification Method: Protein G Purified
Regulatory Status: RUO
Primary or Secondary: Primary
Target Species: Human, Rat
Form: Purified
Antigen:
EYS
Classification:
Monoclonal
Formulation:
Purified mouse monoclonal IgG2bκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.
Gene Symbols:
EYS; C6orf178; C6orf179; C6orf180; EGFL10; EGFL11; SPAM; UNQ9424/PRO34591
Immunogen:
GST-tagged recombinant human EYS fragment corresponding to the EGF-like domains 9-11.
Quantity:
100 μg
Research Discipline:
Neuroscience
Gene ID (Entrez):
NP_001136272
Content And Storage:
Stable for one year at 2°C to 8°C from date of receipt.
Isotype:
IgG2b κ
Applications:
Immunohistochemistry (Paraffin), Western Blot
Clone:
3G10.1
Gene Accession No.:
Q5T1H1
Host Species:
Mouse
Purification Method:
Protein G Purified
Regulatory Status:
RUO
Primary or Secondary:
Primary
Target Species:
Human, Rat
Form:
Purified