MABN807

MilliporeSigma™ Mouse anti-EYS, Clone: 3G10.1,

Manufacturer: MilliporeSigma™

Select a Size

Pack Size SKU Availability Price
Each of 1 MABN807-Each-of-1 In Stock ₹ 38,734.72

MABN807 - Each of 1

₹ 38,734.72

In Stock

Quantity

1

Base Price: ₹ 38,734.72

GST (18%): ₹ 6,972.25

Total Price: ₹ 45,706.97

Antigen

EYS

Classification

Monoclonal

Formulation

Purified mouse monoclonal IgG2bκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.

Gene Symbols

EYS; C6orf178; C6orf179; C6orf180; EGFL10; EGFL11; SPAM; UNQ9424/PRO34591

Immunogen

GST-tagged recombinant human EYS fragment corresponding to the EGF-like domains 9-11.

Quantity

100 μg

Research Discipline

Neuroscience

Gene ID (Entrez)

NP_001136272

Content And Storage

Stable for one year at 2°C to 8°C from date of receipt.

Isotype

IgG2b κ

Applications

Immunohistochemistry (Paraffin), Western Blot

Clone

3G10.1

Gene Accession No.

Q5T1H1

Host Species

Mouse

Purification Method

Protein G Purified

Regulatory Status

RUO

Primary or Secondary

Primary

Target Species

Human, Rat

Form

Purified

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Description

  • Specifically detects EYS clone: 3G10.1 in Human, Rat samples, and it is validated for Immunohistochemistry (Paraffin), Western Blotting Protein eyes shut homolog (UniProt Q5T1H1; also known as EGF-like protein 10, EGF-like protein 11, Epidermal growth factor-like protein 10, Epidermal growth factor-like protein 11, Protein spacemaker homolog) is encoded by the EYS (also known as C6orf178, C6orf179, C6orf180, EGFL10, EGFL11, SPAM) gene (ORF UNQ9424/PRO34591, Gene ID 346007) in human
  • Drosophila eyes shut protein is expressed in photoreceptor cells, the central nervous system, and peripheral sensory ganglia, and is essential for the formation of a matrix-filled intra-rhabdomeral space within the fly's retina ommatidia, the loss of spacemaker (spam) converts an open rhabdom system to a closed one
  • Human EYS/SPAM gene likewise is found to be expressed in the eye and the spinal cord, and mutations in human EYS result in retinitis pigmentosa
  • Human EYS protein contains 27 EGF-like repeats and five laminin G-like (LG1-5) domains (between EGF repeats 21 & 21, 21 & 22, 23 & 24, 25 & 26, and after repeat EGF repeat 27)
  • The presence of the EGF-like repeats is indicative of a role in the Notch signaling pathway, while EYS LG1-5 bear resemblance to the three agrin laminin G domains that are known to interact with several proteins, including α-dystroglycan at the muscle surface.

Compare Similar Items

Show Difference

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MilliporeSigma™

MABN807

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Antigen:
EYS

Classification:
Monoclonal

Formulation:
Purified mouse monoclonal IgG2bκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.

Gene Symbols:
EYS; C6orf178; C6orf179; C6orf180; EGFL10; EGFL11; SPAM; UNQ9424/PRO34591

Immunogen:
GST-tagged recombinant human EYS fragment corresponding to the EGF-like domains 9-11.

Quantity:
100 μg

Research Discipline:
Neuroscience

Gene ID (Entrez):
NP_001136272

Content And Storage:
Stable for one year at 2°C to 8°C from date of receipt.

Isotype:
IgG2b κ

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
3G10.1

Gene Accession No.:
Q5T1H1

Host Species:
Mouse

Purification Method:
Protein G Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human, Rat

Form:
Purified

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MABN812MI

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Antigen:
VPS4A

Classification:
Monoclonal

Formulation:
Purified mouse monoclonal IgG2aκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.

Gene Symbols:
VPS4A; VPS4

Immunogen:
GST-tagged recombinant protein corresponding to human VPS4A sequence at the N-terminus.

Quantity:
100 μg

Research Discipline:
Neuroscience

Gene ID (Entrez):
NP_037377

Content And Storage:
Stable for one year at 2°C to 8°C from date of receipt.

Isotype:
IgG2a κ

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
14B1.1

Gene Accession No.:
Q9UN37

Host Species:
Mouse

Purification Method:
Protein G Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human, Rat

Form:
Purified

Img

MilliporeSigma™

MABN814MI

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Antigen:
Twinkle

Classification:
Monoclonal

Formulation:
Purified mouse monoclonal IgG2aκ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.

Gene Symbols:
EPO1; C10orf2

Immunogen:
GST-tagged recombinant protein corresponding to the C-terminal of human Twinkle.

Quantity:
100 μg

Research Discipline:
Neuroscience

Gene ID (Entrez):
NP_068602

Content And Storage:
Stable for one year at 2°C to 8°C from date of receipt.

Isotype:
IgG2a κ

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
13A10.1

Gene Accession No.:
Q96RR1

Host Species:
Mouse

Purification Method:
Protein G Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human

Form:
Purified

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MABN816

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Antigen:
Ninjurin-1/NINJ1

Classification:
Monoclonal

Formulation:
Purified mouse monoclonal IgG1κ antibody in buffer containing 0.1M Tris-Glycine (pH 7.4), 150mM NaCl with 0.05% sodium azide.

Gene Symbols:
NINJ1; NIN1; NINJURIN

Immunogen:
GST-tagged recombinant human Ninjurin-1/NINJ1 N-terminal extracellular domain.

Quantity:
100 μg

Research Discipline:
Neuroscience

Gene ID (Entrez):
NP_004139

Content And Storage:
Stable for one year at 2°C to 8°C from date of receipt.

Isotype:
IgG1 κ

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
12H6.1

Gene Accession No.:
Q92982

Host Species:
Mouse

Purification Method:
Protein G Purified

Regulatory Status:
RUO

Primary or Secondary:
Primary

Target Species:
Human

Form:
Purified